Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BID | CASP3 | ENSBTAP00000040367 | ENSBTAP00000021099 | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Belongs to the peptidase C14A family. | 0.755 |
| BID | CASP7 | ENSBTAP00000040367 | ENSBTAP00000008706 | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. | Caspase 7; Belongs to the peptidase C14A family. | 0.551 |
| BID | CASP8 | ENSBTAP00000040367 | ENSBTAP00000062824 | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. | Caspase 8, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. | 0.981 |
| BID | LOC505326 | ENSBTAP00000040367 | ENSBTAP00000074467 | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. | 0.921 |
| BID | MCL1 | ENSBTAP00000040367 | ENSBTAP00000020159 | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. | MCL1 protein. | 0.905 |
| CASP3 | BID | ENSBTAP00000021099 | ENSBTAP00000040367 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Belongs to the peptidase C14A family. | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. | 0.755 |
| CASP3 | CASP7 | ENSBTAP00000021099 | ENSBTAP00000008706 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Belongs to the peptidase C14A family. | Caspase 7; Belongs to the peptidase C14A family. | 0.916 |
| CASP3 | CASP8 | ENSBTAP00000021099 | ENSBTAP00000062824 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Belongs to the peptidase C14A family. | Caspase 8, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. | 0.997 |
| CASP3 | DFFA | ENSBTAP00000021099 | ENSBTAP00000017999 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Belongs to the peptidase C14A family. | DNAation factor, 45kDa, alpha polypeptide. | 0.956 |
| CASP3 | LMNA | ENSBTAP00000021099 | ENSBTAP00000023373 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Belongs to the peptidase C14A family. | Lamin A/C; Belongs to the intermediate filament family. | 0.699 |
| CASP3 | LMNB1 | ENSBTAP00000021099 | ENSBTAP00000069937 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Belongs to the peptidase C14A family. | LMNB1 protein; Belongs to the intermediate filament family. | 0.770 |
| CASP3 | LOC505326 | ENSBTAP00000021099 | ENSBTAP00000074467 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Belongs to the peptidase C14A family. | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. | 0.964 |
| CASP3 | MCL1 | ENSBTAP00000021099 | ENSBTAP00000020159 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Belongs to the peptidase C14A family. | MCL1 protein. | 0.945 |
| CASP3 | PARP1 | ENSBTAP00000021099 | ENSBTAP00000059409 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Belongs to the peptidase C14A family. | Poly [ADP-ribose] polymerase 1; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. Mainly mediates glutamate and aspartate ADP-ribosylation of target proteins: the ADP-D-ribosyl group of NAD(+) is transferred to the acceptor carboxyl group of glutamate and aspartate residues and further ADP- ribosyl groups are transferred to the 2'-position of the terminal adenosine moiety, building up a polymer with an average chain length of 20-30 units. Mediates the poly(ADP-ribosyl)ation of a number of proteins, including itself, APLF an [...] | 0.995 |
| CASP3 | PARP4 | ENSBTAP00000021099 | ENSBTAP00000072437 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Belongs to the peptidase C14A family. | Poly [ADP-ribose] polymerase. | 0.919 |
| CASP7 | BID | ENSBTAP00000008706 | ENSBTAP00000040367 | Caspase 7; Belongs to the peptidase C14A family. | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. | 0.551 |
| CASP7 | CASP3 | ENSBTAP00000008706 | ENSBTAP00000021099 | Caspase 7; Belongs to the peptidase C14A family. | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Belongs to the peptidase C14A family. | 0.916 |
| CASP7 | CASP8 | ENSBTAP00000008706 | ENSBTAP00000062824 | Caspase 7; Belongs to the peptidase C14A family. | Caspase 8, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. | 0.973 |
| CASP7 | LMNA | ENSBTAP00000008706 | ENSBTAP00000023373 | Caspase 7; Belongs to the peptidase C14A family. | Lamin A/C; Belongs to the intermediate filament family. | 0.418 |
| CASP7 | LOC505326 | ENSBTAP00000008706 | ENSBTAP00000074467 | Caspase 7; Belongs to the peptidase C14A family. | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. | 0.926 |
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