STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BSP5Seminal plasma protein BSP-30 kDa; Binds to spermatozoa upon ejaculation and may play a role in sperm capacitation. Displays heparin-, gelatin- and phospholipid- binding activities; Belongs to the seminal plasma protein family. (183 aa)    
Predicted Functional Partners:
SPADH2
Spermadhesin Z13; May be involved in the fertilization process; Belongs to the spermadhesin family.
    
 
 0.793
SPADH1
Spermadhesin-1; Stimulates cell division and progesterone secretion of bovine granulosa cells in vitro in a potent and dose dependent manner. This protein appears to be a potent growth factor with effects on ovarian granulosa cells.
   
 
 0.769
ZNF575
Uncharacterized protein.
      
 0.743
PHLDB3
Pleckstrin homology like domain family B member 3.
      
 0.735
WBP2NL
Postacrosomal sheath WW domain-binding protein; May play a role in meotic resumption and pronuclear formation, mediated by a WW domain-signaling pathway during fertilization.
      
 0.627
TIMP2
Metalloproteinase inhibitor 2; Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor; Belongs to the protease inhibitor I35 (TIMP) family.
   
 
 0.594
LOC100295548
Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family.
    
 
 0.593
LYPD3
LY6/PLAUR domain containing 3.
      
 0.591
LCN6
Uncharacterized protein; Belongs to the calycin superfamily. Lipocalin family.
    
 
 0.585
TEX101
Testis expressed 101.
      
 0.577
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.