STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NKPD1NTPase KAP family P-loop domain containing 1. (828 aa)    
Predicted Functional Partners:
ZNF34
Zinc finger protein 34; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
    
 
 0.822
CLASRP
CLK4-associating serine/arginine rich protein; Probably functions as an alternative splicing regulator. May regulate the mRNA splicing of genes such as CLK1. May act by regulating members of the CLK kinase family (By similarity); Belongs to the splicing factor SR family.
      
 0.749
TRAPPC6A
Trafficking protein particle complex subunit 6A; May play a role in vesicular transport during the biogenesis of melanosomes.
 
  
 
 0.711
SH2D3C
SH2 domain containing 3C.
    
 
 0.696
GEMIN7
Gem-associated protein 7; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chapero [...]
      
 0.662
LIPG
Lipase G, endothelial type.
    
 
 0.617
KLK11
Kallikrein related peptidase 11; Belongs to the peptidase S1 family.
   
 
 0.605
ENSBTAP00000061824
Uncharacterized protein.
    
   0.605
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2.
    
 
 0.598
CLPTM1
Cleft lip and palate transmembrane protein 1 homolog; May play a role in T-cell development; Belongs to the CLPTM1 family.
      
 0.590
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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