Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EGFR | JAK1 | ENSBTAP00000070620 | ENSBTAP00000004101 | Receptor protein-tyrosine kinase. | Tyrosine-protein kinase. | 0.960 |
| EGFR | JAK2 | ENSBTAP00000070620 | ENSBTAP00000015986 | Receptor protein-tyrosine kinase. | Tyrosine-protein kinase. | 0.966 |
| EGFR | LOC100335490 | ENSBTAP00000070620 | ENSBTAP00000052781 | Receptor protein-tyrosine kinase. | Uncharacterized protein. | 0.718 |
| EGFR | STAT1 | ENSBTAP00000070620 | ENSBTAP00000067158 | Receptor protein-tyrosine kinase. | Signal transducer and activator of transcription. | 0.918 |
| IFNAR1 | IFNAR2 | ENSBTAP00000029080 | ENSBTAP00000020239 | Interferon alpha/beta receptor 1; Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1. Functions in general as heterodimer with IFNAR2. Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta-subunits themselves (By similarity). Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway (By similarity). | Interferon alpha/beta receptor 2; Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN- mediated STAT1, STAT2 and STAT3 activation. Mediates signal transduction via its association with the TYR kinase, JAK1. | 0.999 |
| IFNAR1 | IL10RB | ENSBTAP00000029080 | ENSBTAP00000025852 | Interferon alpha/beta receptor 1; Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1. Functions in general as heterodimer with IFNAR2. Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta-subunits themselves (By similarity). Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway (By similarity). | Interleukin 10 receptor subunit beta. | 0.566 |
| IFNAR1 | IRF3 | ENSBTAP00000029080 | ENSBTAP00000031815 | Interferon alpha/beta receptor 1; Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1. Functions in general as heterodimer with IFNAR2. Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta-subunits themselves (By similarity). Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway (By similarity). | Interferon regulatory factor 3; Key transcriptional regulator of type I interferon (IFN)- dependent immune responses which plays a critical role in the innate immune response against DNA and RNA viruses. Regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN- stimulated genes (ISG) by binding to an interferon-stimulated response element (ISRE) in their promoters. Acts as a more potent activator of the IFN-beta (IFNB) gene than the IFN-alpha (IFNA) gene and plays a critical role in both the early and late phases of the IFNA/B gene induction. Found in an inactiv [...] | 0.919 |
| IFNAR1 | IRF7 | ENSBTAP00000029080 | ENSBTAP00000059765 | Interferon alpha/beta receptor 1; Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1. Functions in general as heterodimer with IFNAR2. Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta-subunits themselves (By similarity). Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway (By similarity). | Interferon regulatory factor 7. | 0.827 |
| IFNAR1 | JAK1 | ENSBTAP00000029080 | ENSBTAP00000004101 | Interferon alpha/beta receptor 1; Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1. Functions in general as heterodimer with IFNAR2. Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta-subunits themselves (By similarity). Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway (By similarity). | Tyrosine-protein kinase. | 0.999 |
| IFNAR1 | JAK2 | ENSBTAP00000029080 | ENSBTAP00000015986 | Interferon alpha/beta receptor 1; Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1. Functions in general as heterodimer with IFNAR2. Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta-subunits themselves (By similarity). Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway (By similarity). | Tyrosine-protein kinase. | 0.971 |
| IFNAR1 | LOC100335490 | ENSBTAP00000029080 | ENSBTAP00000052781 | Interferon alpha/beta receptor 1; Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1. Functions in general as heterodimer with IFNAR2. Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta-subunits themselves (By similarity). Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway (By similarity). | Uncharacterized protein. | 0.963 |
| IFNAR1 | STAT1 | ENSBTAP00000029080 | ENSBTAP00000067158 | Interferon alpha/beta receptor 1; Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1. Functions in general as heterodimer with IFNAR2. Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta-subunits themselves (By similarity). Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway (By similarity). | Signal transducer and activator of transcription. | 0.995 |
| IFNAR2 | IFNAR1 | ENSBTAP00000020239 | ENSBTAP00000029080 | Interferon alpha/beta receptor 2; Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN- mediated STAT1, STAT2 and STAT3 activation. Mediates signal transduction via its association with the TYR kinase, JAK1. | Interferon alpha/beta receptor 1; Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1. Functions in general as heterodimer with IFNAR2. Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta-subunits themselves (By similarity). Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway (By similarity). | 0.999 |
| IFNAR2 | IL10RB | ENSBTAP00000020239 | ENSBTAP00000025852 | Interferon alpha/beta receptor 2; Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN- mediated STAT1, STAT2 and STAT3 activation. Mediates signal transduction via its association with the TYR kinase, JAK1. | Interleukin 10 receptor subunit beta. | 0.805 |
| IFNAR2 | IRF3 | ENSBTAP00000020239 | ENSBTAP00000031815 | Interferon alpha/beta receptor 2; Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN- mediated STAT1, STAT2 and STAT3 activation. Mediates signal transduction via its association with the TYR kinase, JAK1. | Interferon regulatory factor 3; Key transcriptional regulator of type I interferon (IFN)- dependent immune responses which plays a critical role in the innate immune response against DNA and RNA viruses. Regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN- stimulated genes (ISG) by binding to an interferon-stimulated response element (ISRE) in their promoters. Acts as a more potent activator of the IFN-beta (IFNB) gene than the IFN-alpha (IFNA) gene and plays a critical role in both the early and late phases of the IFNA/B gene induction. Found in an inactiv [...] | 0.545 |
| IFNAR2 | IRF7 | ENSBTAP00000020239 | ENSBTAP00000059765 | Interferon alpha/beta receptor 2; Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN- mediated STAT1, STAT2 and STAT3 activation. Mediates signal transduction via its association with the TYR kinase, JAK1. | Interferon regulatory factor 7. | 0.577 |
| IFNAR2 | JAK1 | ENSBTAP00000020239 | ENSBTAP00000004101 | Interferon alpha/beta receptor 2; Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN- mediated STAT1, STAT2 and STAT3 activation. Mediates signal transduction via its association with the TYR kinase, JAK1. | Tyrosine-protein kinase. | 0.997 |
| IFNAR2 | JAK2 | ENSBTAP00000020239 | ENSBTAP00000015986 | Interferon alpha/beta receptor 2; Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN- mediated STAT1, STAT2 and STAT3 activation. Mediates signal transduction via its association with the TYR kinase, JAK1. | Tyrosine-protein kinase. | 0.947 |
| IFNAR2 | LOC100335490 | ENSBTAP00000020239 | ENSBTAP00000052781 | Interferon alpha/beta receptor 2; Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN- mediated STAT1, STAT2 and STAT3 activation. Mediates signal transduction via its association with the TYR kinase, JAK1. | Uncharacterized protein. | 0.939 |
| IFNAR2 | STAT1 | ENSBTAP00000020239 | ENSBTAP00000067158 | Interferon alpha/beta receptor 2; Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN- mediated STAT1, STAT2 and STAT3 activation. Mediates signal transduction via its association with the TYR kinase, JAK1. | Signal transducer and activator of transcription. | 0.989 |
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