node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
IER3IP1 | TMEM167A | ENSBTAP00000044053 | ENSBTAP00000053007 | Immediate early response 3-interacting protein 1; May be implicated in the regulation of apoptosis. May be involved in protein transport between endoplasmic reticulum and Golgi apparatus; Belongs to the YOS1 family. | Protein kish-A; Involved in the early part of the secretory pathway. Belongs to the KISH family. | 0.582 |
IER3IP1 | YIPF5 | ENSBTAP00000044053 | ENSBTAP00000016956 | Immediate early response 3-interacting protein 1; May be implicated in the regulation of apoptosis. May be involved in protein transport between endoplasmic reticulum and Golgi apparatus; Belongs to the YOS1 family. | Protein YIPF5; Plays a role in transport between endoplasmic reticulum and Golgi. | 0.512 |
MFSD6 | ORMDL2 | ENSBTAP00000058509 | ENSBTAP00000027540 | Major facilitator superfamily domain containing 6. | ORM1-like protein 2; Negative regulator of sphingolipid synthesis; Belongs to the ORM family. | 0.580 |
MFSD6 | RRP36 | ENSBTAP00000058509 | ENSBTAP00000044278 | Major facilitator superfamily domain containing 6. | Ribosomal RNA processing protein 36 homolog; Involved in the early processing steps of the pre-rRNA in the maturation pathway leading to the 18S rRNA; Belongs to the RRP36 family. | 0.569 |
MFSD6 | SLC25A51 | ENSBTAP00000058509 | ENSBTAP00000019883 | Major facilitator superfamily domain containing 6. | MCART1 protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.487 |
MFSD6 | SPTSSA | ENSBTAP00000058509 | ENSBTAP00000018578 | Major facilitator superfamily domain containing 6. | Serine palmitoyltransferase small subunit A; Stimulates the activity of serine palmitoyltransferase (SPT). The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference. The SPTLC1-SPTLC2-SPTSSA complex shows a strong preference for C16-CoA substrate, while the SPTLC1- SPTLC3-SPTSSA isozyme uses both C14-CoA and C16-CoA as substrates, with a slight preference for C14-CoA. Plays a role in MBOAT7 location to mitochondria-associated membranes (MAMs), may me involved in fatty acid remodeling phosphatidylinositol (PI). | 0.480 |
MFSD6 | TEFM | ENSBTAP00000058509 | ENSBTAP00000024467 | Major facilitator superfamily domain containing 6. | Transcription elongation factor, mitochondrial; Transcription elongation factor which increases mitochondrial RNA polymerase processivity. Regulates transcription of the mitochondrial genome, including genes important for the oxidative phosphorylation machinery (By similarity). | 0.441 |
MFSD6 | TMEM167A | ENSBTAP00000058509 | ENSBTAP00000053007 | Major facilitator superfamily domain containing 6. | Protein kish-A; Involved in the early part of the secretory pathway. Belongs to the KISH family. | 0.626 |
NPM3 | TMEM167A | ENSBTAP00000021730 | ENSBTAP00000053007 | Nucleophosmin/nucleoplasmin 3. | Protein kish-A; Involved in the early part of the secretory pathway. Belongs to the KISH family. | 0.674 |
NPM3 | VGLL4 | ENSBTAP00000021730 | ENSBTAP00000062249 | Nucleophosmin/nucleoplasmin 3. | Vestigial like family member 4. | 0.584 |
ORMDL2 | MFSD6 | ENSBTAP00000027540 | ENSBTAP00000058509 | ORM1-like protein 2; Negative regulator of sphingolipid synthesis; Belongs to the ORM family. | Major facilitator superfamily domain containing 6. | 0.580 |
ORMDL2 | RRP36 | ENSBTAP00000027540 | ENSBTAP00000044278 | ORM1-like protein 2; Negative regulator of sphingolipid synthesis; Belongs to the ORM family. | Ribosomal RNA processing protein 36 homolog; Involved in the early processing steps of the pre-rRNA in the maturation pathway leading to the 18S rRNA; Belongs to the RRP36 family. | 0.621 |
ORMDL2 | SLC25A51 | ENSBTAP00000027540 | ENSBTAP00000019883 | ORM1-like protein 2; Negative regulator of sphingolipid synthesis; Belongs to the ORM family. | MCART1 protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.537 |
ORMDL2 | SPTSSA | ENSBTAP00000027540 | ENSBTAP00000018578 | ORM1-like protein 2; Negative regulator of sphingolipid synthesis; Belongs to the ORM family. | Serine palmitoyltransferase small subunit A; Stimulates the activity of serine palmitoyltransferase (SPT). The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference. The SPTLC1-SPTLC2-SPTSSA complex shows a strong preference for C16-CoA substrate, while the SPTLC1- SPTLC3-SPTSSA isozyme uses both C14-CoA and C16-CoA as substrates, with a slight preference for C14-CoA. Plays a role in MBOAT7 location to mitochondria-associated membranes (MAMs), may me involved in fatty acid remodeling phosphatidylinositol (PI). | 0.912 |
ORMDL2 | TEFM | ENSBTAP00000027540 | ENSBTAP00000024467 | ORM1-like protein 2; Negative regulator of sphingolipid synthesis; Belongs to the ORM family. | Transcription elongation factor, mitochondrial; Transcription elongation factor which increases mitochondrial RNA polymerase processivity. Regulates transcription of the mitochondrial genome, including genes important for the oxidative phosphorylation machinery (By similarity). | 0.480 |
ORMDL2 | TMEM167A | ENSBTAP00000027540 | ENSBTAP00000053007 | ORM1-like protein 2; Negative regulator of sphingolipid synthesis; Belongs to the ORM family. | Protein kish-A; Involved in the early part of the secretory pathway. Belongs to the KISH family. | 0.677 |
RRP36 | MFSD6 | ENSBTAP00000044278 | ENSBTAP00000058509 | Ribosomal RNA processing protein 36 homolog; Involved in the early processing steps of the pre-rRNA in the maturation pathway leading to the 18S rRNA; Belongs to the RRP36 family. | Major facilitator superfamily domain containing 6. | 0.569 |
RRP36 | ORMDL2 | ENSBTAP00000044278 | ENSBTAP00000027540 | Ribosomal RNA processing protein 36 homolog; Involved in the early processing steps of the pre-rRNA in the maturation pathway leading to the 18S rRNA; Belongs to the RRP36 family. | ORM1-like protein 2; Negative regulator of sphingolipid synthesis; Belongs to the ORM family. | 0.621 |
RRP36 | SLC25A51 | ENSBTAP00000044278 | ENSBTAP00000019883 | Ribosomal RNA processing protein 36 homolog; Involved in the early processing steps of the pre-rRNA in the maturation pathway leading to the 18S rRNA; Belongs to the RRP36 family. | MCART1 protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.564 |
RRP36 | SPTSSA | ENSBTAP00000044278 | ENSBTAP00000018578 | Ribosomal RNA processing protein 36 homolog; Involved in the early processing steps of the pre-rRNA in the maturation pathway leading to the 18S rRNA; Belongs to the RRP36 family. | Serine palmitoyltransferase small subunit A; Stimulates the activity of serine palmitoyltransferase (SPT). The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference. The SPTLC1-SPTLC2-SPTSSA complex shows a strong preference for C16-CoA substrate, while the SPTLC1- SPTLC3-SPTSSA isozyme uses both C14-CoA and C16-CoA as substrates, with a slight preference for C14-CoA. Plays a role in MBOAT7 location to mitochondria-associated membranes (MAMs), may me involved in fatty acid remodeling phosphatidylinositol (PI). | 0.497 |