node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABHD15 | ANKS4B | ENSBTAP00000035132 | ENSBTAP00000012963 | Abhydrolase domain containing 15. | Ankyrin repeat and sterile alpha motif domain containing 4B. | 0.822 |
ABHD15 | GPR39 | ENSBTAP00000035132 | ENSBTAP00000053900 | Abhydrolase domain containing 15. | G-protein coupled receptor 39; Zn(2+) acts as an agonist. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Its effect is mediated mainly through G(q)-alpha and G(12)/G(13) proteins. Involved in regulation of body weight, gastrointestinal mobility, hormone secretion and cell death (By similarity). | 0.685 |
AIG1 | GPR39 | ENSBTAP00000004546 | ENSBTAP00000053900 | Androgen induced 1. | G-protein coupled receptor 39; Zn(2+) acts as an agonist. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Its effect is mediated mainly through G(q)-alpha and G(12)/G(13) proteins. Involved in regulation of body weight, gastrointestinal mobility, hormone secretion and cell death (By similarity). | 0.654 |
AIG1 | RBM33 | ENSBTAP00000004546 | ENSBTAP00000020368 | Androgen induced 1. | RNA binding motif protein 33. | 0.795 |
AIG1 | TESPA1 | ENSBTAP00000004546 | ENSBTAP00000006753 | Androgen induced 1. | Thymocyte expressed, positive selection associated 1. | 0.836 |
ANKS4B | ABHD15 | ENSBTAP00000012963 | ENSBTAP00000035132 | Ankyrin repeat and sterile alpha motif domain containing 4B. | Abhydrolase domain containing 15. | 0.822 |
ANKS4B | GPR39 | ENSBTAP00000012963 | ENSBTAP00000053900 | Ankyrin repeat and sterile alpha motif domain containing 4B. | G-protein coupled receptor 39; Zn(2+) acts as an agonist. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Its effect is mediated mainly through G(q)-alpha and G(12)/G(13) proteins. Involved in regulation of body weight, gastrointestinal mobility, hormone secretion and cell death (By similarity). | 0.601 |
GHRL | GPR39 | ENSBTAP00000041811 | ENSBTAP00000053900 | Appetite-regulating hormone; Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation (By similarity). | G-protein coupled receptor 39; Zn(2+) acts as an agonist. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Its effect is mediated mainly through G(q)-alpha and G(12)/G(13) proteins. Involved in regulation of body weight, gastrointestinal mobility, hormone secretion and cell death (By similarity). | 0.768 |
GHRL | MLN | ENSBTAP00000041811 | ENSBTAP00000020661 | Appetite-regulating hormone; Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation (By similarity). | Motilin-associated peptide; Plays an important role in the regulation of interdigestive gastrointestinal motility and indirectly causes rhythmic contraction of duodenal and colonic smooth muscle; Belongs to the motilin family. | 0.919 |
GHRL | NTS | ENSBTAP00000041811 | ENSBTAP00000006980 | Appetite-regulating hormone; Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation (By similarity). | Neurotensin/neuromedin N; Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle; Belongs to the neurotensin family. | 0.865 |
GPR39 | ABHD15 | ENSBTAP00000053900 | ENSBTAP00000035132 | G-protein coupled receptor 39; Zn(2+) acts as an agonist. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Its effect is mediated mainly through G(q)-alpha and G(12)/G(13) proteins. Involved in regulation of body weight, gastrointestinal mobility, hormone secretion and cell death (By similarity). | Abhydrolase domain containing 15. | 0.685 |
GPR39 | AIG1 | ENSBTAP00000053900 | ENSBTAP00000004546 | G-protein coupled receptor 39; Zn(2+) acts as an agonist. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Its effect is mediated mainly through G(q)-alpha and G(12)/G(13) proteins. Involved in regulation of body weight, gastrointestinal mobility, hormone secretion and cell death (By similarity). | Androgen induced 1. | 0.654 |
GPR39 | ANKS4B | ENSBTAP00000053900 | ENSBTAP00000012963 | G-protein coupled receptor 39; Zn(2+) acts as an agonist. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Its effect is mediated mainly through G(q)-alpha and G(12)/G(13) proteins. Involved in regulation of body weight, gastrointestinal mobility, hormone secretion and cell death (By similarity). | Ankyrin repeat and sterile alpha motif domain containing 4B. | 0.601 |
GPR39 | GHRL | ENSBTAP00000053900 | ENSBTAP00000041811 | G-protein coupled receptor 39; Zn(2+) acts as an agonist. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Its effect is mediated mainly through G(q)-alpha and G(12)/G(13) proteins. Involved in regulation of body weight, gastrointestinal mobility, hormone secretion and cell death (By similarity). | Appetite-regulating hormone; Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation (By similarity). | 0.768 |
GPR39 | GPR65 | ENSBTAP00000053900 | ENSBTAP00000040515 | G-protein coupled receptor 39; Zn(2+) acts as an agonist. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Its effect is mediated mainly through G(q)-alpha and G(12)/G(13) proteins. Involved in regulation of body weight, gastrointestinal mobility, hormone secretion and cell death (By similarity). | G protein-coupled receptor 65; Belongs to the G-protein coupled receptor 1 family. | 0.670 |
GPR39 | GPR68 | ENSBTAP00000053900 | ENSBTAP00000008858 | G-protein coupled receptor 39; Zn(2+) acts as an agonist. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Its effect is mediated mainly through G(q)-alpha and G(12)/G(13) proteins. Involved in regulation of body weight, gastrointestinal mobility, hormone secretion and cell death (By similarity). | Ovarian cancer G-protein coupled receptor 1; Proton-sensing receptor involved in pH homeostasis. May represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. Mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca(2+) mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8 (By similarity). Also functions as a metastasis suppressor gene in prostate cancer (By similarity); Belongs to the G-protein coupled receptor 1 family. | 0.687 |
GPR39 | MLN | ENSBTAP00000053900 | ENSBTAP00000020661 | G-protein coupled receptor 39; Zn(2+) acts as an agonist. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Its effect is mediated mainly through G(q)-alpha and G(12)/G(13) proteins. Involved in regulation of body weight, gastrointestinal mobility, hormone secretion and cell death (By similarity). | Motilin-associated peptide; Plays an important role in the regulation of interdigestive gastrointestinal motility and indirectly causes rhythmic contraction of duodenal and colonic smooth muscle; Belongs to the motilin family. | 0.653 |
GPR39 | NTS | ENSBTAP00000053900 | ENSBTAP00000006980 | G-protein coupled receptor 39; Zn(2+) acts as an agonist. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Its effect is mediated mainly through G(q)-alpha and G(12)/G(13) proteins. Involved in regulation of body weight, gastrointestinal mobility, hormone secretion and cell death (By similarity). | Neurotensin/neuromedin N; Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle; Belongs to the neurotensin family. | 0.663 |
GPR39 | RBM33 | ENSBTAP00000053900 | ENSBTAP00000020368 | G-protein coupled receptor 39; Zn(2+) acts as an agonist. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Its effect is mediated mainly through G(q)-alpha and G(12)/G(13) proteins. Involved in regulation of body weight, gastrointestinal mobility, hormone secretion and cell death (By similarity). | RNA binding motif protein 33. | 0.608 |
GPR39 | TESPA1 | ENSBTAP00000053900 | ENSBTAP00000006753 | G-protein coupled receptor 39; Zn(2+) acts as an agonist. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Its effect is mediated mainly through G(q)-alpha and G(12)/G(13) proteins. Involved in regulation of body weight, gastrointestinal mobility, hormone secretion and cell death (By similarity). | Thymocyte expressed, positive selection associated 1. | 0.650 |