STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C1RLUncharacterized protein; Complement component 1, r subcomponent-like; Belongs to the peptidase S1 family (492 aa)    
Predicted Functional Partners:
CDADC1
Uncharacterized protein; Cytidine and dCMP deaminase domain containing 1
   
  
 0.674
AMZ1
Archaelysin family metallopeptidase 1
      
 0.668
EML1
Echinoderm microtubule associated protein like 1
      
 0.619
SBF2
Bos taurus SET binding factor 2 (SBF2), mRNA; Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily
      
 0.616
DDX54
DEAD-box helicase 54; DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
    
 
 0.603
RANBP17
RAN binding protein 17
      
 0.557
C9
Complement component C9; Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C9 is the pore-forming subunit of the MAC; Belongs to the complement C6/C7/C8/C9 family
   
 
 0.549
OPCML
Opioid-binding protein/cell adhesion molecule; Binds opioids in the presence of acidic lipids; probably involved in cell contact
    
 
 0.548
C4BPA
C4b-binding protein alpha chain; Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. Alpha chain binds C4b. It interacts also with serum amyloid P component
      
 0.535
C1R
Uncharacterized protein; Complement component 1, r subcomponent
   
 
0.528
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bos taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, domestic cattle, domestic cow
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