node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FFAR1 | FFAR4 | ENSBTAP00000055089 | ENSBTAP00000000560 | Free fatty acid receptor 1. | G protein-coupled receptor 120. | 0.936 |
FFAR1 | GCG | ENSBTAP00000055089 | ENSBTAP00000000972 | Free fatty acid receptor 1. | Glicentin-related polypeptide; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia (By similarity). GLP-2 stimulates intestinal growth and up-regulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. The gastrointestinal tract, from the stomach to the colon is the principal target for GLP-2 action. Plays a [...] | 0.855 |
FFAR1 | GIP | ENSBTAP00000055089 | ENSBTAP00000006656 | Free fatty acid receptor 1. | Gastric inhibitory polypeptide; Potent stimulator of insulin secretion and relatively poor inhibitor of gastric acid secretion; Belongs to the glucagon family. | 0.854 |
FFAR1 | GNA11 | ENSBTAP00000055089 | ENSBTAP00000050620 | Free fatty acid receptor 1. | Guanine nucleotide-binding protein subunit alpha-11; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. | 0.914 |
FFAR1 | GNAQ | ENSBTAP00000055089 | ENSBTAP00000016160 | Free fatty acid receptor 1. | G protein subunit alpha q. | 0.914 |
FFAR1 | GPBAR1 | ENSBTAP00000055089 | ENSBTAP00000005120 | Free fatty acid receptor 1. | G-protein coupled bile acid receptor 1; Receptor for bile acid. Bile acid-binding induces its internalization, activation of extracellular signal-regulated kinase and intracellular cAMP production. May be involved in the suppression of macrophage functions by bile acids. Involved in bile acid promoted GLP1R secretion (By similarity). | 0.686 |
FFAR1 | GPR119 | ENSBTAP00000055089 | ENSBTAP00000019647 | Free fatty acid receptor 1. | G protein-coupled receptor 119; Belongs to the G-protein coupled receptor 1 family. | 0.819 |
FFAR1 | GPR142 | ENSBTAP00000055089 | ENSBTAP00000070379 | Free fatty acid receptor 1. | G protein-coupled receptor 142; Belongs to the G-protein coupled receptor 1 family. | 0.742 |
FFAR1 | GPR75 | ENSBTAP00000055089 | ENSBTAP00000000111 | Free fatty acid receptor 1. | G protein-coupled receptor 75. | 0.781 |
FFAR1 | GPR84 | ENSBTAP00000055089 | ENSBTAP00000020710 | Free fatty acid receptor 1. | G-protein coupled receptor 84; Receptor for medium-chain free fatty acid (FFA) with carbon chain lengths of C9 to C14. Capric acid (C10:0), undecanoic acid (C11:0) and lauric acid (C12:0) are the most potent agonists. Not activated by short-chain and long-chain saturated and unsaturated FFAs. Activation by medium-chain free fatty acid is coupled to a pertussis toxin sensitive G(i/o) protein pathway. May have important roles in processes from fatty acid metabolism to regulation of the immune system (By similarity). | 0.699 |
FFAR4 | FFAR1 | ENSBTAP00000000560 | ENSBTAP00000055089 | G protein-coupled receptor 120. | Free fatty acid receptor 1. | 0.936 |
FFAR4 | GCG | ENSBTAP00000000560 | ENSBTAP00000000972 | G protein-coupled receptor 120. | Glicentin-related polypeptide; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia (By similarity). GLP-2 stimulates intestinal growth and up-regulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. The gastrointestinal tract, from the stomach to the colon is the principal target for GLP-2 action. Plays a [...] | 0.901 |
FFAR4 | GIP | ENSBTAP00000000560 | ENSBTAP00000006656 | G protein-coupled receptor 120. | Gastric inhibitory polypeptide; Potent stimulator of insulin secretion and relatively poor inhibitor of gastric acid secretion; Belongs to the glucagon family. | 0.481 |
FFAR4 | GPBAR1 | ENSBTAP00000000560 | ENSBTAP00000005120 | G protein-coupled receptor 120. | G-protein coupled bile acid receptor 1; Receptor for bile acid. Bile acid-binding induces its internalization, activation of extracellular signal-regulated kinase and intracellular cAMP production. May be involved in the suppression of macrophage functions by bile acids. Involved in bile acid promoted GLP1R secretion (By similarity). | 0.567 |
FFAR4 | GPR119 | ENSBTAP00000000560 | ENSBTAP00000019647 | G protein-coupled receptor 120. | G protein-coupled receptor 119; Belongs to the G-protein coupled receptor 1 family. | 0.796 |
FFAR4 | GPR142 | ENSBTAP00000000560 | ENSBTAP00000070379 | G protein-coupled receptor 120. | G protein-coupled receptor 142; Belongs to the G-protein coupled receptor 1 family. | 0.481 |
FFAR4 | GPR84 | ENSBTAP00000000560 | ENSBTAP00000020710 | G protein-coupled receptor 120. | G-protein coupled receptor 84; Receptor for medium-chain free fatty acid (FFA) with carbon chain lengths of C9 to C14. Capric acid (C10:0), undecanoic acid (C11:0) and lauric acid (C12:0) are the most potent agonists. Not activated by short-chain and long-chain saturated and unsaturated FFAs. Activation by medium-chain free fatty acid is coupled to a pertussis toxin sensitive G(i/o) protein pathway. May have important roles in processes from fatty acid metabolism to regulation of the immune system (By similarity). | 0.774 |
GCG | FFAR1 | ENSBTAP00000000972 | ENSBTAP00000055089 | Glicentin-related polypeptide; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia (By similarity). GLP-2 stimulates intestinal growth and up-regulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. The gastrointestinal tract, from the stomach to the colon is the principal target for GLP-2 action. Plays a [...] | Free fatty acid receptor 1. | 0.855 |
GCG | FFAR4 | ENSBTAP00000000972 | ENSBTAP00000000560 | Glicentin-related polypeptide; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia (By similarity). GLP-2 stimulates intestinal growth and up-regulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. The gastrointestinal tract, from the stomach to the colon is the principal target for GLP-2 action. Plays a [...] | G protein-coupled receptor 120. | 0.901 |
GCG | GIP | ENSBTAP00000000972 | ENSBTAP00000006656 | Glicentin-related polypeptide; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia (By similarity). GLP-2 stimulates intestinal growth and up-regulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. The gastrointestinal tract, from the stomach to the colon is the principal target for GLP-2 action. Plays a [...] | Gastric inhibitory polypeptide; Potent stimulator of insulin secretion and relatively poor inhibitor of gastric acid secretion; Belongs to the glucagon family. | 0.901 |