STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPACA5Sperm acrosome-associated protein 5; Belongs to the glycosyl hydrolase 22 family. (156 aa)    
Predicted Functional Partners:
TMEM190
Transmembrane protein 190.
   
  
 0.790
PPP1R2
Protein phosphatase inhibitor 2; Inhibitor of protein-phosphatase 1.
      
 0.759
CYLC1
Cylicin-1; Possible architectural role during spermatogenesis. May be involved in spermatid differentiation.
      
 0.719
FSIP2
Fibrous sheath interacting protein 2.
      
 0.689
AKAP14
A-kinase anchoring protein 14.
      
 0.663
AK7
Adenylate kinase 7.
   
  
 0.661
IZUMO2
KRAB domain-containing protein.
   
  
 0.653
ACTRT1
Actin related protein T1; Belongs to the actin family.
   
  
 0.624
ODF4
Outer dense fiber protein 4; Component of the outer dense fibers (ODF) of spermatozoa which could be involved in sperm tail structure, sperm movement and general organization of cellular cytoskeleton.
      
 0.614
SPATA9
Spermatogenesis-associated protein 9; May play at role in testicular development/spermatogenesis and may be an important factor in male infertility.
      
 0.610
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.