STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARL16ADP ribosylation factor like GTPase 16. (258 aa)    
Predicted Functional Partners:
USP21
Ubiquitin carboxyl-terminal hydrolase 21; Deubiquitinates histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A releaves the repression of di- and trimethylation of histone H3 at 'Lys-4', resulting in regulation of transcriptional initiation. Regulates gene expression via histone H2A deubiquitination. Also capable of removing NEDD8 from NEDD8 conjugates but has no effect on Sentrin-1 conjugates. Deubiquitinates BAZ2A/TIP5 leading to its stabilization; Belongs to the peptidase C19 family. USP21 subfamily.
   
 
 0.928
ARL13A
ADP ribosylation factor like GTPase 13A.
      
 0.886
IRF2BP1
Uncharacterized protein.
    
 
 0.812
RNF125
Uncharacterized protein.
    
 
 0.791
ARL9
ADP ribosylation factor like GTPase 9.
    
 
 0.744
ARL5B
ADP ribosylation factor like GTPase 5B; Belongs to the small GTPase superfamily. Arf family.
    
 
 0.675
DOCK1
Dedicator of cytokinesis 1; Belongs to the DOCK family.
      
 0.671
CGREF1
Uncharacterized protein.
      
 0.659
FMN1
Formin 1.
    
 
 0.640
ACTR10
Actin-related protein 10.
    
 
 0.635
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.