| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| dsbD | ytfB | STM4323 | STM4396 | Thiol:disulfide interchange protein; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. | Putative cell envelope opacity-associated protein A; Similar to E. coli orf, hypothetical protein (AAC77163.1); Blastp hit to AAC77163.1 (224 aa), 85% identity in aa 13 - 224. | 0.445 |
| exo | ytfB | STM2972 | STM4396 | Exonuclease IX, 5'-3' exonuclease; Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. | Putative cell envelope opacity-associated protein A; Similar to E. coli orf, hypothetical protein (AAC77163.1); Blastp hit to AAC77163.1 (224 aa), 85% identity in aa 13 - 224. | 0.541 |
| fklB | rplV | STM4397 | STM3435 | Similar to E. coli FKBP-type 22KD peptidyl-prolyl cis-trans isomerase (rotamase) (AAC77164.1); Blastp hit to AAC77164.1 (259 aa), 92% identity in aa 41 - 259. | 50S ribosomal subunit protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). | 0.510 |
| fklB | ytfB | STM4397 | STM4396 | Similar to E. coli FKBP-type 22KD peptidyl-prolyl cis-trans isomerase (rotamase) (AAC77164.1); Blastp hit to AAC77164.1 (259 aa), 92% identity in aa 41 - 259. | Putative cell envelope opacity-associated protein A; Similar to E. coli orf, hypothetical protein (AAC77163.1); Blastp hit to AAC77163.1 (224 aa), 85% identity in aa 13 - 224. | 0.544 |
| lepB | ytfB | STM2582 | STM4396 | Leader peptidase (signal peptidase I), serine protease; Signal peptidase I. (SW:LEP_SALTY); Belongs to the peptidase S26 family. | Putative cell envelope opacity-associated protein A; Similar to E. coli orf, hypothetical protein (AAC77163.1); Blastp hit to AAC77163.1 (224 aa), 85% identity in aa 13 - 224. | 0.445 |
| rplV | fklB | STM3435 | STM4397 | 50S ribosomal subunit protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). | Similar to E. coli FKBP-type 22KD peptidyl-prolyl cis-trans isomerase (rotamase) (AAC77164.1); Blastp hit to AAC77164.1 (259 aa), 92% identity in aa 41 - 259. | 0.510 |
| rplV | ytfB | STM3435 | STM4396 | 50S ribosomal subunit protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). | Putative cell envelope opacity-associated protein A; Similar to E. coli orf, hypothetical protein (AAC77163.1); Blastp hit to AAC77163.1 (224 aa), 85% identity in aa 13 - 224. | 0.852 |
| ytfB | dsbD | STM4396 | STM4323 | Putative cell envelope opacity-associated protein A; Similar to E. coli orf, hypothetical protein (AAC77163.1); Blastp hit to AAC77163.1 (224 aa), 85% identity in aa 13 - 224. | Thiol:disulfide interchange protein; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. | 0.445 |
| ytfB | exo | STM4396 | STM2972 | Putative cell envelope opacity-associated protein A; Similar to E. coli orf, hypothetical protein (AAC77163.1); Blastp hit to AAC77163.1 (224 aa), 85% identity in aa 13 - 224. | Exonuclease IX, 5'-3' exonuclease; Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. | 0.541 |
| ytfB | fklB | STM4396 | STM4397 | Putative cell envelope opacity-associated protein A; Similar to E. coli orf, hypothetical protein (AAC77163.1); Blastp hit to AAC77163.1 (224 aa), 85% identity in aa 13 - 224. | Similar to E. coli FKBP-type 22KD peptidyl-prolyl cis-trans isomerase (rotamase) (AAC77164.1); Blastp hit to AAC77164.1 (259 aa), 92% identity in aa 41 - 259. | 0.544 |
| ytfB | lepB | STM4396 | STM2582 | Putative cell envelope opacity-associated protein A; Similar to E. coli orf, hypothetical protein (AAC77163.1); Blastp hit to AAC77163.1 (224 aa), 85% identity in aa 13 - 224. | Leader peptidase (signal peptidase I), serine protease; Signal peptidase I. (SW:LEP_SALTY); Belongs to the peptidase S26 family. | 0.445 |
| ytfB | rplV | STM4396 | STM3435 | Putative cell envelope opacity-associated protein A; Similar to E. coli orf, hypothetical protein (AAC77163.1); Blastp hit to AAC77163.1 (224 aa), 85% identity in aa 13 - 224. | 50S ribosomal subunit protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). | 0.852 |