STRINGSTRING
SNAT protein (Ovis aries) - STRING interaction network
"SNAT" - Serotonin N-acetyltransferase in Ovis aries
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SNATSerotonin N-acetyltransferase; Controls the night/day rhythm of melatonin production in the pineal gland. Catalyzes the N-acetylation of serotonin into N- acetylserotonin, the penultimate step in the synthesis of melatonin; Belongs to the acetyltransferase family. AANAT subfamily (207 aa)    
Predicted Functional Partners:
ASMT
Acetylserotonin O-methyltransferase (276 aa)
     
 
  0.991
DDC
Dopa decarboxylase (aromatic L-amino acid decarboxylase) (543 aa)
       
  0.926
MAOB
Monoamine oxidase B (451 aa)
     
 
  0.910
MAOA
Amine oxidase [flavin-containing] A; Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine (By similarity) (527 aa)
     
 
  0.910
IDO1
Ovis aries indoleamine 2,3-dioxygenase 1 (IDO1), mRNA (410 aa)
         
  0.901
ENSOARG00000007808
Uncharacterized protein (263 aa)
         
    0.900
IDO2
Indoleamine 2,3-dioxygenase 2 (407 aa)
         
    0.900
SLC38A2
Solute carrier family 38, member 2 (560 aa)
           
  0.815
AANAT
Uncharacterized protein; Ovis aries aralkylamine N-acetyltransferase (AANAT), mRNA (207 aa)
   
   
0.802
SEC61G
Sec61 gamma subunit (68 aa)
     
        0.643
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
Server load: low (17%) [HD]