node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALDOA | ALDOB | ENSOARP00000004428 | ENSOARP00000008061 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Fructose-bisphosphate aldolase B. | 0.979 |
ALDOA | ALDOC | ENSOARP00000004428 | ENSOARP00000000489 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | 0.973 |
ALDOA | FBP1 | ENSOARP00000004428 | ENSOARP00000009283 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Fructose-1,6-bisphosphatase 1; Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. Appears to modulate glycerol gluconeogenesis in liver. Important regulator of appetite and adiposity; increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism [...] | 0.970 |
ALDOA | FBP2 | ENSOARP00000004428 | ENSOARP00000009302 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Fructose-bisphosphatase 2; Belongs to the FBPase class 1 family. | 0.975 |
ALDOA | GAPDH | ENSOARP00000004428 | ENSOARP00000008476 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] | 0.989 |
ALDOA | PFKL | ENSOARP00000004428 | ENSOARP00000012730 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. | 0.982 |
ALDOA | PFKM | ENSOARP00000004428 | ENSOARP00000020732 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. | 0.989 |
ALDOA | TKT | ENSOARP00000004428 | ENSOARP00000017958 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Transketolase. | 0.975 |
ALDOA | TKTL1 | ENSOARP00000004428 | ENSOARP00000005897 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Transketolase like 1. | 0.975 |
ALDOA | TPI1 | ENSOARP00000004428 | ENSOARP00000005822 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Triosephosphate isomerase. | 0.994 |
ALDOB | ALDOA | ENSOARP00000008061 | ENSOARP00000004428 | Fructose-bisphosphate aldolase B. | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | 0.979 |
ALDOB | ALDOC | ENSOARP00000008061 | ENSOARP00000000489 | Fructose-bisphosphate aldolase B. | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | 0.961 |
ALDOB | FBP1 | ENSOARP00000008061 | ENSOARP00000009283 | Fructose-bisphosphate aldolase B. | Fructose-1,6-bisphosphatase 1; Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. Appears to modulate glycerol gluconeogenesis in liver. Important regulator of appetite and adiposity; increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism [...] | 0.975 |
ALDOB | FBP2 | ENSOARP00000008061 | ENSOARP00000009302 | Fructose-bisphosphate aldolase B. | Fructose-bisphosphatase 2; Belongs to the FBPase class 1 family. | 0.983 |
ALDOB | GAPDH | ENSOARP00000008061 | ENSOARP00000008476 | Fructose-bisphosphate aldolase B. | Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] | 0.970 |
ALDOB | PFKL | ENSOARP00000008061 | ENSOARP00000012730 | Fructose-bisphosphate aldolase B. | ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. | 0.987 |
ALDOB | PFKM | ENSOARP00000008061 | ENSOARP00000020732 | Fructose-bisphosphate aldolase B. | ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. | 0.985 |
ALDOB | TKT | ENSOARP00000008061 | ENSOARP00000017958 | Fructose-bisphosphate aldolase B. | Transketolase. | 0.971 |
ALDOB | TKTL1 | ENSOARP00000008061 | ENSOARP00000005897 | Fructose-bisphosphate aldolase B. | Transketolase like 1. | 0.978 |
ALDOB | TPI1 | ENSOARP00000008061 | ENSOARP00000005822 | Fructose-bisphosphate aldolase B. | Triosephosphate isomerase. | 0.987 |