node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AMH | BMP15 | ENSOARP00000015429 | ENSOARP00000010055 | AMH_N domain-containing protein. | Bone morphogenetic protein 15; May be involved in follicular development. Oocyte-specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth (By similarity). | 0.929 |
AMH | BMPR1B | ENSOARP00000015429 | ENSOARP00000018416 | AMH_N domain-containing protein. | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | 0.857 |
AMH | BMPR2 | ENSOARP00000015429 | ENSOARP00000018927 | AMH_N domain-containing protein. | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | 0.948 |
AMH | FIGLA | ENSOARP00000015429 | ENSOARP00000012007 | AMH_N domain-containing protein. | BHLH domain-containing protein. | 0.531 |
AMH | FSHR | ENSOARP00000015429 | ENSOARP00000004647 | AMH_N domain-containing protein. | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. The activity of isoform FSH-R1 is mediated by G proteins which activate adenylate cyclase. Isoform FSH-R2 and isoform FSH-R3 also bind FSH, but this does not result in activation of adenylate cyclase. Isoform FSH-R3 may be involved in calcium signaling. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways (By similarity). | 0.946 |
AMH | GDF9 | ENSOARP00000015429 | ENSOARP00000014175 | AMH_N domain-containing protein. | Growth/differentiation factor 9; Required for ovarian folliculogenesis. | 0.940 |
AMH | INHA | ENSOARP00000015429 | ENSOARP00000021737 | AMH_N domain-containing protein. | Inhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins; Belongs to the TGF-beta family. | 0.658 |
AMH | LHCGR | ENSOARP00000015429 | ENSOARP00000004768 | AMH_N domain-containing protein. | Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. | 0.885 |
AMH | SMAD2 | ENSOARP00000015429 | ENSOARP00000003900 | AMH_N domain-containing protein. | Mothers against decapentaplegic homolog. | 0.460 |
BMP15 | AMH | ENSOARP00000010055 | ENSOARP00000015429 | Bone morphogenetic protein 15; May be involved in follicular development. Oocyte-specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth (By similarity). | AMH_N domain-containing protein. | 0.929 |
BMP15 | BMPR1B | ENSOARP00000010055 | ENSOARP00000018416 | Bone morphogenetic protein 15; May be involved in follicular development. Oocyte-specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth (By similarity). | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | 0.997 |
BMP15 | BMPR2 | ENSOARP00000010055 | ENSOARP00000018927 | Bone morphogenetic protein 15; May be involved in follicular development. Oocyte-specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth (By similarity). | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | 0.991 |
BMP15 | FIGLA | ENSOARP00000010055 | ENSOARP00000012007 | Bone morphogenetic protein 15; May be involved in follicular development. Oocyte-specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth (By similarity). | BHLH domain-containing protein. | 0.758 |
BMP15 | FSHR | ENSOARP00000010055 | ENSOARP00000004647 | Bone morphogenetic protein 15; May be involved in follicular development. Oocyte-specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth (By similarity). | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. The activity of isoform FSH-R1 is mediated by G proteins which activate adenylate cyclase. Isoform FSH-R2 and isoform FSH-R3 also bind FSH, but this does not result in activation of adenylate cyclase. Isoform FSH-R3 may be involved in calcium signaling. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways (By similarity). | 0.937 |
BMP15 | GDF9 | ENSOARP00000010055 | ENSOARP00000014175 | Bone morphogenetic protein 15; May be involved in follicular development. Oocyte-specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth (By similarity). | Growth/differentiation factor 9; Required for ovarian folliculogenesis. | 0.894 |
BMP15 | INHA | ENSOARP00000010055 | ENSOARP00000021737 | Bone morphogenetic protein 15; May be involved in follicular development. Oocyte-specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth (By similarity). | Inhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins; Belongs to the TGF-beta family. | 0.782 |
BMP15 | LHCGR | ENSOARP00000010055 | ENSOARP00000004768 | Bone morphogenetic protein 15; May be involved in follicular development. Oocyte-specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth (By similarity). | Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. | 0.859 |
BMP15 | SMAD2 | ENSOARP00000010055 | ENSOARP00000003900 | Bone morphogenetic protein 15; May be involved in follicular development. Oocyte-specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth (By similarity). | Mothers against decapentaplegic homolog. | 0.815 |
BMP15 | ZP2 | ENSOARP00000010055 | ENSOARP00000015528 | Bone morphogenetic protein 15; May be involved in follicular development. Oocyte-specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth (By similarity). | Zona pellucida glycoprotein 2. | 0.843 |
BMPR1B | AMH | ENSOARP00000018416 | ENSOARP00000015429 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | AMH_N domain-containing protein. | 0.857 |