node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALB | CSN1S1 | ENSOARP00000014782 | ENSOARP00000011026 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Alpha-S1-casein; Important role in the capacity of milk to transport calcium phosphate. | 0.474 |
ALB | CSN2 | ENSOARP00000014782 | ENSOARP00000011245 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Beta-casein; Important role in determination of the surface properties of the casein micelles; Belongs to the beta-casein family. | 0.797 |
ALB | CSN3 | ENSOARP00000014782 | ENSOARP00000011880 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Kappa-casein; Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk. | 0.749 |
ALB | CYM | ENSOARP00000014782 | ENSOARP00000020902 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Chymosin; Chymosin is synthesized in the mucosa of the stomach. The enzyme hydrolyzes casein to paracasein. | 0.436 |
ALB | LACB_SHEEP | ENSOARP00000014782 | ENSOARP00000005471 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Beta-lactoglobulin-1/B; Lactoglobulin is the primary component of whey, it binds retinol and is probably involved in the transport of that molecule; Belongs to the calycin superfamily. Lipocalin family. | 0.999 |
ALB | LALBA | ENSOARP00000014782 | ENSOARP00000020650 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Alpha-lactalbumin; Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N- acetylglucosamine of the oligosaccharide chains in glycoproteins; Belongs to the glycosyl hydrolase 22 family. | 0.991 |
ALB | LPO | ENSOARP00000014782 | ENSOARP00000009607 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Uncharacterized protein. | 0.747 |
ALB | LTF | ENSOARP00000014782 | ENSOARP00000009256 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Uncharacterized protein; Belongs to the transferrin family. | 0.946 |
CSN1S1 | ALB | ENSOARP00000011026 | ENSOARP00000014782 | Alpha-S1-casein; Important role in the capacity of milk to transport calcium phosphate. | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | 0.474 |
CSN1S1 | CSN1S2 | ENSOARP00000011026 | ENSOARP00000011473 | Alpha-S1-casein; Important role in the capacity of milk to transport calcium phosphate. | Alpha-S2-casein; Important role in the capacity of milk to transport calcium phosphate. | 0.998 |
CSN1S1 | CSN2 | ENSOARP00000011026 | ENSOARP00000011245 | Alpha-S1-casein; Important role in the capacity of milk to transport calcium phosphate. | Beta-casein; Important role in determination of the surface properties of the casein micelles; Belongs to the beta-casein family. | 0.984 |
CSN1S1 | CSN3 | ENSOARP00000011026 | ENSOARP00000011880 | Alpha-S1-casein; Important role in the capacity of milk to transport calcium phosphate. | Kappa-casein; Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk. | 0.973 |
CSN1S1 | CYM | ENSOARP00000011026 | ENSOARP00000020902 | Alpha-S1-casein; Important role in the capacity of milk to transport calcium phosphate. | Chymosin; Chymosin is synthesized in the mucosa of the stomach. The enzyme hydrolyzes casein to paracasein. | 0.822 |
CSN1S1 | GLYCAM1 | ENSOARP00000011026 | ENSOARP00000017271 | Alpha-S1-casein; Important role in the capacity of milk to transport calcium phosphate. | Uncharacterized protein. | 0.786 |
CSN1S1 | LACB_SHEEP | ENSOARP00000011026 | ENSOARP00000005471 | Alpha-S1-casein; Important role in the capacity of milk to transport calcium phosphate. | Beta-lactoglobulin-1/B; Lactoglobulin is the primary component of whey, it binds retinol and is probably involved in the transport of that molecule; Belongs to the calycin superfamily. Lipocalin family. | 0.870 |
CSN1S1 | LALBA | ENSOARP00000011026 | ENSOARP00000020650 | Alpha-S1-casein; Important role in the capacity of milk to transport calcium phosphate. | Alpha-lactalbumin; Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N- acetylglucosamine of the oligosaccharide chains in glycoproteins; Belongs to the glycosyl hydrolase 22 family. | 0.987 |
CSN1S1 | LPO | ENSOARP00000011026 | ENSOARP00000009607 | Alpha-S1-casein; Important role in the capacity of milk to transport calcium phosphate. | Uncharacterized protein. | 0.572 |
CSN1S1 | LTF | ENSOARP00000011026 | ENSOARP00000009256 | Alpha-S1-casein; Important role in the capacity of milk to transport calcium phosphate. | Uncharacterized protein; Belongs to the transferrin family. | 0.695 |
CSN1S2 | CSN1S1 | ENSOARP00000011473 | ENSOARP00000011026 | Alpha-S2-casein; Important role in the capacity of milk to transport calcium phosphate. | Alpha-S1-casein; Important role in the capacity of milk to transport calcium phosphate. | 0.998 |
CSN1S2 | CSN2 | ENSOARP00000011473 | ENSOARP00000011245 | Alpha-S2-casein; Important role in the capacity of milk to transport calcium phosphate. | Beta-casein; Important role in determination of the surface properties of the casein micelles; Belongs to the beta-casein family. | 0.962 |