CA2 protein (Ovis aries) - STRING interaction network

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CA2

Carbonic anhydrase 2; Essential for bone resorption and osteoclast differentiation. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6 (By similarity). Reversible hydration of carbon dioxide. (263 aa)

Predicted Functional Partners:

CA1

0.795

SLC4A1

0.760

LOC101103165

0.727

SLC9A1

0.714

CTSK

0.643

CBS

0.636

SLC4A4

0.621

SLC4A2

0.586

AASDHPPT

0.581

MB

0.577

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AASDHPPT	CA2	ENSOARP00000002765	ENSOARP00000013878	Aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase.	Carbonic anhydrase 2; Essential for bone resorption and osteoclast differentiation. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6 (By similarity). Reversible hydration of carbon dioxide.	0.581
CA1	CA2	ENSOARP00000014236	ENSOARP00000013878	Carbonic anhydrase 1; Reversible hydration of carbon dioxide.	Carbonic anhydrase 2; Essential for bone resorption and osteoclast differentiation. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6 (By similarity). Reversible hydration of carbon dioxide.	0.795
CA1	SLC4A1	ENSOARP00000014236	ENSOARP00000008399	Carbonic anhydrase 1; Reversible hydration of carbon dioxide.	Anion exchange protein.	0.632
CA2	AASDHPPT	ENSOARP00000013878	ENSOARP00000002765	Carbonic anhydrase 2; Essential for bone resorption and osteoclast differentiation. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6 (By similarity). Reversible hydration of carbon dioxide.	Aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase.	0.581
CA2	CA1	ENSOARP00000013878	ENSOARP00000014236	Carbonic anhydrase 2; Essential for bone resorption and osteoclast differentiation. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6 (By similarity). Reversible hydration of carbon dioxide.	Carbonic anhydrase 1; Reversible hydration of carbon dioxide.	0.795
CA2	CBS	ENSOARP00000013878	ENSOARP00000011930	Carbonic anhydrase 2; Essential for bone resorption and osteoclast differentiation. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6 (By similarity). Reversible hydration of carbon dioxide.	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.	0.636
CA2	CTSK	ENSOARP00000013878	ENSOARP00000022430	Carbonic anhydrase 2; Essential for bone resorption and osteoclast differentiation. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6 (By similarity). Reversible hydration of carbon dioxide.	Cathepsin K; Belongs to the peptidase C1 family.	0.643
CA2	LOC101103165	ENSOARP00000013878	ENSOARP00000006903	Carbonic anhydrase 2; Essential for bone resorption and osteoclast differentiation. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6 (By similarity). Reversible hydration of carbon dioxide.	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.727
CA2	MB	ENSOARP00000013878	ENSOARP00000020014	Carbonic anhydrase 2; Essential for bone resorption and osteoclast differentiation. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6 (By similarity). Reversible hydration of carbon dioxide.	Myoglobin; Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.	0.577
CA2	SLC4A1	ENSOARP00000013878	ENSOARP00000008399	Carbonic anhydrase 2; Essential for bone resorption and osteoclast differentiation. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6 (By similarity). Reversible hydration of carbon dioxide.	Anion exchange protein.	0.760
CA2	SLC4A2	ENSOARP00000013878	ENSOARP00000002988	Carbonic anhydrase 2; Essential for bone resorption and osteoclast differentiation. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6 (By similarity). Reversible hydration of carbon dioxide.	Anion exchange protein.	0.586
CA2	SLC4A4	ENSOARP00000013878	ENSOARP00000013270	Carbonic anhydrase 2; Essential for bone resorption and osteoclast differentiation. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6 (By similarity). Reversible hydration of carbon dioxide.	Anion exchange protein.	0.621
CA2	SLC9A1	ENSOARP00000013878	ENSOARP00000004093	Carbonic anhydrase 2; Essential for bone resorption and osteoclast differentiation. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6 (By similarity). Reversible hydration of carbon dioxide.	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.	0.714
CBS	CA2	ENSOARP00000011930	ENSOARP00000013878	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.	Carbonic anhydrase 2; Essential for bone resorption and osteoclast differentiation. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6 (By similarity). Reversible hydration of carbon dioxide.	0.636
CTSK	CA2	ENSOARP00000022430	ENSOARP00000013878	Cathepsin K; Belongs to the peptidase C1 family.	Carbonic anhydrase 2; Essential for bone resorption and osteoclast differentiation. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6 (By similarity). Reversible hydration of carbon dioxide.	0.643
LOC101103165	CA2	ENSOARP00000006903	ENSOARP00000013878	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Carbonic anhydrase 2; Essential for bone resorption and osteoclast differentiation. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6 (By similarity). Reversible hydration of carbon dioxide.	0.727
MB	CA2	ENSOARP00000020014	ENSOARP00000013878	Myoglobin; Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.	Carbonic anhydrase 2; Essential for bone resorption and osteoclast differentiation. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6 (By similarity). Reversible hydration of carbon dioxide.	0.577
SLC4A1	CA1	ENSOARP00000008399	ENSOARP00000014236	Anion exchange protein.	Carbonic anhydrase 1; Reversible hydration of carbon dioxide.	0.632
SLC4A1	CA2	ENSOARP00000008399	ENSOARP00000013878	Anion exchange protein.	Carbonic anhydrase 2; Essential for bone resorption and osteoclast differentiation. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6 (By similarity). Reversible hydration of carbon dioxide.	0.760
SLC4A2	CA2	ENSOARP00000002988	ENSOARP00000013878	Anion exchange protein.	Carbonic anhydrase 2; Essential for bone resorption and osteoclast differentiation. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6 (By similarity). Reversible hydration of carbon dioxide.	0.586

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