close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MACROH2A1macroH2A.1 histone. (372 aa)    
Predicted Functional Partners:
MYSM1
Myb like, SWIRM and MPN domains 1.
  
 0.996
SPOP
Speckle type BTB/POZ protein.
    
 
 0.942
PARP1
poly(ADP-ribose) polymerase 1.
    
 
 0.927
HDAC2
Histone deacetylase 2.
   
 0.925
ENSSDAP00000002367
annotation not available
   
 0.921
KDM6A
Lysine demethylase 6A.
   
 0.921
HDAC3
Histone deacetylase 3.
   
 0.912
HDAC11
Histone deacetylase 11.
   
 0.907
ENSSDAP00000027380
annotation not available
   
 0.905
ENSSDAP00000007757
annotation not available
   
 0.900
Your Current Organism:
Spermophilus dauricus
NCBI taxonomy Id: 99837
Other names: Citellus dauricus, Daurian ground squirrel, S. dauricus
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