STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
YWHAH14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (309 aa)    
Predicted Functional Partners:
ARAF
A-Raf proto-oncogene, serine/threonine kinase.
   
 0.976
RAF1
Raf-1 proto-oncogene, serine/threonine kinase.
   
 0.970
CDC25C
Cell division cycle 25C.
    
 0.957
FOXO3
Fork-head domain-containing protein.
    
 0.956
WWTR1
WW domain containing transcription regulator 1.
    
 0.955
YAP1
Yes associated protein 1.
    
 0.955
CTNNA1
Catenin alpha-1; Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E- and N-cadherins. Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be much more dynamic than E-cadherin/catenin complexes and [...]
     
 0.929
CTNNA2
Catenin alpha 2.
     
 0.929
CTNNA3
Catenin alpha 3.
     
 0.924
LOC100341681
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
    
 0.912
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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