node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CA2 | SLC26A3 | ENSOCUP00000032692 | ENSOCUP00000018950 | Carbonic anhydrase 2; Essential for bone resorption and osteoclast differentiation. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6 (By similarity). Reversible hydration of carbon dioxide; Belongs to the alpha-carbonic anhydrase family. | Chloride anion exchanger; Chloride/bicarbonate exchanger. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. | 0.468 |
CA2 | SLC26A4 | ENSOCUP00000032692 | ENSOCUP00000049992 | Carbonic anhydrase 2; Essential for bone resorption and osteoclast differentiation. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6 (By similarity). Reversible hydration of carbon dioxide; Belongs to the alpha-carbonic anhydrase family. | Pendrin; Sodium-independent transporter of chloride and iodide. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. | 0.686 |
CA2 | SLC26A6 | ENSOCUP00000032692 | ENSOCUP00000000544 | Carbonic anhydrase 2; Essential for bone resorption and osteoclast differentiation. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6 (By similarity). Reversible hydration of carbon dioxide; Belongs to the alpha-carbonic anhydrase family. | Solute carrier family 26 member 6. | 0.575 |
CA2 | SLC26A7 | ENSOCUP00000032692 | ENSOCUP00000044037 | Carbonic anhydrase 2; Essential for bone resorption and osteoclast differentiation. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6 (By similarity). Reversible hydration of carbon dioxide; Belongs to the alpha-carbonic anhydrase family. | Anion exchange transporter; Acts as a sodium-independent DIDS-sensitive anion exchanger mediating bicarbonate, chloride, sulfate and oxalate transport. May play a role in the maintenance of the electrolyte and acid-base homeostasis in the kidney, by acting as a distal excretory segment- specific anion exchanger. Plays a major role in gastric acid secretion (By similarity). | 0.478 |
CA2 | SLC4A3 | ENSOCUP00000032692 | ENSOCUP00000009785 | Carbonic anhydrase 2; Essential for bone resorption and osteoclast differentiation. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6 (By similarity). Reversible hydration of carbon dioxide; Belongs to the alpha-carbonic anhydrase family. | Anion exchange protein 3; Plasma membrane anion exchange protein. | 0.593 |
CCSAP | SLC4A3 | ENSOCUP00000005897 | ENSOCUP00000009785 | Centriole, cilia and spindle associated protein. | Anion exchange protein 3; Plasma membrane anion exchange protein. | 0.518 |
LURAP1L | SLC4A3 | ENSOCUP00000003652 | ENSOCUP00000009785 | Leucine rich adaptor protein 1 like. | Anion exchange protein 3; Plasma membrane anion exchange protein. | 0.687 |
SLC12A2 | SLC26A3 | ENSOCUP00000001558 | ENSOCUP00000018950 | Solute carrier family 12 member 2. | Chloride anion exchanger; Chloride/bicarbonate exchanger. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. | 0.566 |
SLC12A2 | SLC26A4 | ENSOCUP00000001558 | ENSOCUP00000049992 | Solute carrier family 12 member 2. | Pendrin; Sodium-independent transporter of chloride and iodide. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. | 0.677 |
SLC12A2 | SLC26A6 | ENSOCUP00000001558 | ENSOCUP00000000544 | Solute carrier family 12 member 2. | Solute carrier family 26 member 6. | 0.694 |
SLC12A2 | SLC26A7 | ENSOCUP00000001558 | ENSOCUP00000044037 | Solute carrier family 12 member 2. | Anion exchange transporter; Acts as a sodium-independent DIDS-sensitive anion exchanger mediating bicarbonate, chloride, sulfate and oxalate transport. May play a role in the maintenance of the electrolyte and acid-base homeostasis in the kidney, by acting as a distal excretory segment- specific anion exchanger. Plays a major role in gastric acid secretion (By similarity). | 0.578 |
SLC12A2 | SLC26A9 | ENSOCUP00000001558 | ENSOCUP00000021636 | Solute carrier family 12 member 2. | Solute carrier family 26 member 9; DIDS- and thiosulfate- sensitive anion exchanger mediating chloride, sulfate and oxalate transport. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. | 0.574 |
SLC12A2 | SLC4A3 | ENSOCUP00000001558 | ENSOCUP00000009785 | Solute carrier family 12 member 2. | Anion exchange protein 3; Plasma membrane anion exchange protein. | 0.607 |
SLC26A11 | SLC26A3 | ENSOCUP00000006719 | ENSOCUP00000018950 | Solute carrier family 26 member 11. | Chloride anion exchanger; Chloride/bicarbonate exchanger. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. | 0.437 |
SLC26A11 | SLC26A4 | ENSOCUP00000006719 | ENSOCUP00000049992 | Solute carrier family 26 member 11. | Pendrin; Sodium-independent transporter of chloride and iodide. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. | 0.423 |
SLC26A11 | SLC26A7 | ENSOCUP00000006719 | ENSOCUP00000044037 | Solute carrier family 26 member 11. | Anion exchange transporter; Acts as a sodium-independent DIDS-sensitive anion exchanger mediating bicarbonate, chloride, sulfate and oxalate transport. May play a role in the maintenance of the electrolyte and acid-base homeostasis in the kidney, by acting as a distal excretory segment- specific anion exchanger. Plays a major role in gastric acid secretion (By similarity). | 0.444 |
SLC26A11 | SLC26A9 | ENSOCUP00000006719 | ENSOCUP00000021636 | Solute carrier family 26 member 11. | Solute carrier family 26 member 9; DIDS- and thiosulfate- sensitive anion exchanger mediating chloride, sulfate and oxalate transport. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. | 0.434 |
SLC26A11 | SLC4A3 | ENSOCUP00000006719 | ENSOCUP00000009785 | Solute carrier family 26 member 11. | Anion exchange protein 3; Plasma membrane anion exchange protein. | 0.658 |
SLC26A3 | CA2 | ENSOCUP00000018950 | ENSOCUP00000032692 | Chloride anion exchanger; Chloride/bicarbonate exchanger. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. | Carbonic anhydrase 2; Essential for bone resorption and osteoclast differentiation. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6 (By similarity). Reversible hydration of carbon dioxide; Belongs to the alpha-carbonic anhydrase family. | 0.468 |
SLC26A3 | SLC12A2 | ENSOCUP00000018950 | ENSOCUP00000001558 | Chloride anion exchanger; Chloride/bicarbonate exchanger. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. | Solute carrier family 12 member 2. | 0.566 |