node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALB | CSN1S1 | ENSOCUP00000014006 | ENSOCUP00000008181 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Alpha-S1-casein; Important role in the capacity of milk to transport calcium phosphate. | 0.643 |
ALB | CSN2 | ENSOCUP00000014006 | ENSOCUP00000008186 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Beta-casein; Important role in determination of the surface properties of the casein micelles. | 0.689 |
ALB | CSN3 | ENSOCUP00000014006 | ENSOCUP00000036667 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Kappa-casein; Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk. | 0.571 |
ALB | LALBA | ENSOCUP00000014006 | ENSOCUP00000024236 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Alpha-lactalbumin; Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N- acetylglucosamine of the oligosaccharide chains in glycoproteins; Belongs to the glycosyl hydrolase 22 family. | 0.920 |
ALB | LOC100341936 | ENSOCUP00000014006 | ENSOCUP00000025549 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. | 0.706 |
CSN1S1 | ALB | ENSOCUP00000008181 | ENSOCUP00000014006 | Alpha-S1-casein; Important role in the capacity of milk to transport calcium phosphate. | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | 0.643 |
CSN1S1 | CSN2 | ENSOCUP00000008181 | ENSOCUP00000008186 | Alpha-S1-casein; Important role in the capacity of milk to transport calcium phosphate. | Beta-casein; Important role in determination of the surface properties of the casein micelles. | 0.983 |
CSN1S1 | CSN3 | ENSOCUP00000008181 | ENSOCUP00000036667 | Alpha-S1-casein; Important role in the capacity of milk to transport calcium phosphate. | Kappa-casein; Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk. | 0.979 |
CSN1S1 | LALBA | ENSOCUP00000008181 | ENSOCUP00000024236 | Alpha-S1-casein; Important role in the capacity of milk to transport calcium phosphate. | Alpha-lactalbumin; Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N- acetylglucosamine of the oligosaccharide chains in glycoproteins; Belongs to the glycosyl hydrolase 22 family. | 0.965 |
CSN1S1 | LOC100341936 | ENSOCUP00000008181 | ENSOCUP00000025549 | Alpha-S1-casein; Important role in the capacity of milk to transport calcium phosphate. | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. | 0.493 |
CSN1S1 | LOC100354542 | ENSOCUP00000008181 | ENSOCUP00000024690 | Alpha-S1-casein; Important role in the capacity of milk to transport calcium phosphate. | Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. | 0.697 |
CSN1S1 | WAP | ENSOCUP00000008181 | ENSOCUP00000049552 | Alpha-S1-casein; Important role in the capacity of milk to transport calcium phosphate. | Whey acidic protein; Could be a protease inhibitor. | 0.824 |
CSN2 | ALB | ENSOCUP00000008186 | ENSOCUP00000014006 | Beta-casein; Important role in determination of the surface properties of the casein micelles. | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | 0.689 |
CSN2 | CSN1S1 | ENSOCUP00000008186 | ENSOCUP00000008181 | Beta-casein; Important role in determination of the surface properties of the casein micelles. | Alpha-S1-casein; Important role in the capacity of milk to transport calcium phosphate. | 0.983 |
CSN2 | CSN3 | ENSOCUP00000008186 | ENSOCUP00000036667 | Beta-casein; Important role in determination of the surface properties of the casein micelles. | Kappa-casein; Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk. | 0.971 |
CSN2 | LALBA | ENSOCUP00000008186 | ENSOCUP00000024236 | Beta-casein; Important role in determination of the surface properties of the casein micelles. | Alpha-lactalbumin; Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N- acetylglucosamine of the oligosaccharide chains in glycoproteins; Belongs to the glycosyl hydrolase 22 family. | 0.948 |
CSN2 | LOC100341936 | ENSOCUP00000008186 | ENSOCUP00000025549 | Beta-casein; Important role in determination of the surface properties of the casein micelles. | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. | 0.455 |
CSN2 | LOC100354542 | ENSOCUP00000008186 | ENSOCUP00000024690 | Beta-casein; Important role in determination of the surface properties of the casein micelles. | Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. | 0.523 |
CSN2 | WAP | ENSOCUP00000008186 | ENSOCUP00000049552 | Beta-casein; Important role in determination of the surface properties of the casein micelles. | Whey acidic protein; Could be a protease inhibitor. | 0.903 |
CSN3 | ALB | ENSOCUP00000036667 | ENSOCUP00000014006 | Kappa-casein; Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk. | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | 0.571 |