STRINGSTRING
COL12A1 protein (Oryctolagus cuniculus) - STRING interaction network
"COL12A1" - Collagen alpha-1(XII) chain in Oryctolagus cuniculus
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
COL12A1Collagen alpha-1(XII) chain; Type XII collagen interacts with type I collagen- containing fibrils, the COL1 domain could be associated with the surface of the fibrils, and the COL2 and NC3 domains may be localized in the perifibrillar matrix; Belongs to the fibril-associated collagens with interrupted helices (FACIT) family (3121 aa)    
Predicted Functional Partners:
ENSOCUG00000026921
Uncharacterized protein (231 aa)
     
   
  0.631
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1 (887 aa)
     
 
  0.589
COL1A2
Collagen alpha-2(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen); Belongs to the fibrillar collagen family (1364 aa)
     
   
0.563
COL5A2
Collagen, type V, alpha 2 (1502 aa)
     
   
0.551
COL1A1
Collagen alpha-1(I) chain; Collagen, type I, alpha 1 (1195 aa)
     
   
0.538
COL3A1
Collagen, type III, alpha 1 (1464 aa)
     
   
0.536
CNDP2
CNDP dipeptidase 2 (metallopeptidase M20 family) (497 aa)
           
  0.534
SERPINE2
Serpin family E member 2; Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2; Belongs to the serpin family (404 aa)
     
 
  0.506
ADAMTS7
ADAM metallopeptidase with thrombospondin type 1 motif, 7 (1654 aa)
     
 
  0.505
DCN
Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily (360 aa)
     
 
  0.501
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, Oryctolagus cuniculus, domestic rabbit, rabbit, rabbits
Server load: low (12%) [HD]