RNF222 protein (Oryctolagus cuniculus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

RNF222

Ring finger protein 222. (220 aa)

Predicted Functional Partners:

MUC15

0.711

PI15

0.698

GABRP

0.695

NUP210

0.677

GABRD

0.649

BACE2

0.598

CCT2

0.523

LOC103345309

0.495

FNDC3A

0.459

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BACE2	RNF222	ENSOCUP00000023300	ENSOCUP00000014279	Beta-secretase 2; Belongs to the peptidase A1 family.	Ring finger protein 222.	0.598
CCT2	RNF222	ENSOCUP00000047140	ENSOCUP00000014279	Uncharacterized protein.	Ring finger protein 222.	0.523
FNDC3A	RNF222	ENSOCUP00000030414	ENSOCUP00000014279	Fibronectin type III domain containing 3A.	Ring finger protein 222.	0.459
GABRD	RNF222	ENSOCUP00000030774	ENSOCUP00000014279	Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	Ring finger protein 222.	0.649
GABRP	PI15	ENSOCUP00000007078	ENSOCUP00000018551	Gamma-aminobutyric acid type A receptor pi subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	Peptidase inhibitor 15; Belongs to the CRISP family.	0.491
GABRP	RNF222	ENSOCUP00000007078	ENSOCUP00000014279	Gamma-aminobutyric acid type A receptor pi subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	Ring finger protein 222.	0.695
LOC103345309	RNF222	ENSOCUP00000026356	ENSOCUP00000014279	Uncharacterized protein.	Ring finger protein 222.	0.495
MUC15	RNF222	ENSOCUP00000019789	ENSOCUP00000014279	Mucin 15, cell surface associated.	Ring finger protein 222.	0.711
NUP210	RNF222	ENSOCUP00000012244	ENSOCUP00000014279	Nucleoporin 210.	Ring finger protein 222.	0.677
PI15	GABRP	ENSOCUP00000018551	ENSOCUP00000007078	Peptidase inhibitor 15; Belongs to the CRISP family.	Gamma-aminobutyric acid type A receptor pi subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.491
PI15	RNF222	ENSOCUP00000018551	ENSOCUP00000014279	Peptidase inhibitor 15; Belongs to the CRISP family.	Ring finger protein 222.	0.698
RNF222	BACE2	ENSOCUP00000014279	ENSOCUP00000023300	Ring finger protein 222.	Beta-secretase 2; Belongs to the peptidase A1 family.	0.598
RNF222	CCT2	ENSOCUP00000014279	ENSOCUP00000047140	Ring finger protein 222.	Uncharacterized protein.	0.523
RNF222	FNDC3A	ENSOCUP00000014279	ENSOCUP00000030414	Ring finger protein 222.	Fibronectin type III domain containing 3A.	0.459
RNF222	GABRD	ENSOCUP00000014279	ENSOCUP00000030774	Ring finger protein 222.	Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.649
RNF222	GABRP	ENSOCUP00000014279	ENSOCUP00000007078	Ring finger protein 222.	Gamma-aminobutyric acid type A receptor pi subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.695
RNF222	LOC103345309	ENSOCUP00000014279	ENSOCUP00000026356	Ring finger protein 222.	Uncharacterized protein.	0.495
RNF222	MUC15	ENSOCUP00000014279	ENSOCUP00000019789	Ring finger protein 222.	Mucin 15, cell surface associated.	0.711
RNF222	NUP210	ENSOCUP00000014279	ENSOCUP00000012244	Ring finger protein 222.	Nucleoporin 210.	0.677
RNF222	PI15	ENSOCUP00000014279	ENSOCUP00000018551	Ring finger protein 222.	Peptidase inhibitor 15; Belongs to the CRISP family.	0.698