STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
KCNB1Potassium voltage-gated channel subfamily B member 1; Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain, but also in the pancreas and cardiovascular system. Contributes to the regulation of the action potential (AP) repolarization, duration and frequency of repetitive AP firing in neurons, muscle cells and endocrine cells and plays a role in homeostatic attenuation of electrical excitability throughout the brain. Plays also a role in the regulation of exocytosis independently of its electrical function. Forms [...] (858 aa)    
Predicted Functional Partners:
G1U1Y5_RABIT
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
 0.809
FAU
Ubiquitin-like domain-containing protein.
   
 0.809
ENSOCUP00000046875
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
 0.809
ENSOCUP00000049185
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
 0.809
KCNAB1
Voltage-gated potassium channel subunit beta-1; Cytoplasmic potassium channel subunit that modulates the characteristics of the channel-forming alpha-subunits (By similarity). Modulates action potentials via its effect on the pore-forming alpha subunits (By similarity). Promotes expression of the pore-forming alpha subunits at the cell membrane, and thereby increases channel activity (By similarity). Mediates closure of delayed rectifier potassium channels by physically obstructing the pore via its N-terminal domain and increases the speed of channel closure for other family members (B [...]
   
 0.792
KCNAB2
Potassium voltage-gated channel subfamily A regulatory beta subunit 2.
   
 0.718
KCNAB3
Potassium voltage-gated channel subfamily A regulatory beta subunit 3.
   
 0.714
RPLP2
60S acidic ribosomal protein P2; Plays an important role in the elongation step of protein synthesis.
   
 0.691
STX1A
Syntaxin 1A; Belongs to the syntaxin family.
    
 
 0.680
KCNG4
Potassium voltage-gated channel modifier subfamily G member 4; Belongs to the potassium channel family.
  
0.669
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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