node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADA | ALB | ENSOCUP00000008708 | ENSOCUP00000014006 | Adenosine deaminase. | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | 0.443 |
ADA | UOX | ENSOCUP00000008708 | ENSOCUP00000049580 | Adenosine deaminase. | Uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin; Belongs to the uricase family. | 0.701 |
ALB | ADA | ENSOCUP00000014006 | ENSOCUP00000008708 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Adenosine deaminase. | 0.443 |
ALB | TTR | ENSOCUP00000014006 | ENSOCUP00000014907 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain (By similarity). Belongs to the transthyretin family. | 0.935 |
ALB | UOX | ENSOCUP00000014006 | ENSOCUP00000049580 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin; Belongs to the uricase family. | 0.668 |
ALLC | G1TFX3_RABIT | ENSOCUP00000013834 | ENSOCUP00000015820 | Allantoicase. | 5-hydroxyisourate hydrolase; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. | 0.592 |
ALLC | TTR | ENSOCUP00000013834 | ENSOCUP00000014907 | Allantoicase. | Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain (By similarity). Belongs to the transthyretin family. | 0.451 |
ALLC | UOX | ENSOCUP00000013834 | ENSOCUP00000049580 | Allantoicase. | Uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin; Belongs to the uricase family. | 0.782 |
G1TFX3_RABIT | ALLC | ENSOCUP00000015820 | ENSOCUP00000013834 | 5-hydroxyisourate hydrolase; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. | Allantoicase. | 0.592 |
G1TFX3_RABIT | UOX | ENSOCUP00000015820 | ENSOCUP00000049580 | 5-hydroxyisourate hydrolase; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. | Uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin; Belongs to the uricase family. | 0.994 |
G1TFX3_RABIT | URAD | ENSOCUP00000015820 | ENSOCUP00000017661 | 5-hydroxyisourate hydrolase; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. | Ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase. | 0.962 |
G1TFX3_RABIT | XDH | ENSOCUP00000015820 | ENSOCUP00000001068 | 5-hydroxyisourate hydrolase; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. | Uncharacterized protein. | 0.416 |
G1U5P7_RABIT | UOX | ENSOCUP00000024731 | ENSOCUP00000049580 | Uncharacterized protein. | Uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin; Belongs to the uricase family. | 0.696 |
PEX5 | UOX | ENSOCUP00000017055 | ENSOCUP00000049580 | Peroxisomal biogenesis factor 5. | Uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin; Belongs to the uricase family. | 0.623 |
SLC22A6 | UOX | ENSOCUP00000022887 | ENSOCUP00000049580 | Solute carrier family 22 member 6; Involved in the renal elimination of endogenous and exogenous organic anions. Functions as organic anion exchanger when the uptake of one molecule of organic anion is coupled with an efflux of one molecule of endogenous dicarboxylic acid (glutarate, ketoglutarate, etc). Mediates the sodium-independent uptake of cidofovir, adefovir, 9-(2- phosphonylmethoxyethyl) guanine (PMEG), 9-(2-phosphonylmethoxyethyl) diaminopurine (PMEDAP), ochratoxin (OTA), acyclovir (ACV), 3'-azido- 3-'deoxythymidine (AZT), cimetidine (CMD), 2,4-dichloro-phenoxyacetate (2,4-D), [...] | Uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin; Belongs to the uricase family. | 0.672 |
TTR | ALB | ENSOCUP00000014907 | ENSOCUP00000014006 | Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain (By similarity). Belongs to the transthyretin family. | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | 0.935 |
TTR | ALLC | ENSOCUP00000014907 | ENSOCUP00000013834 | Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain (By similarity). Belongs to the transthyretin family. | Allantoicase. | 0.451 |
TTR | UOX | ENSOCUP00000014907 | ENSOCUP00000049580 | Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain (By similarity). Belongs to the transthyretin family. | Uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin; Belongs to the uricase family. | 0.921 |
UOX | ADA | ENSOCUP00000049580 | ENSOCUP00000008708 | Uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin; Belongs to the uricase family. | Adenosine deaminase. | 0.701 |
UOX | ALB | ENSOCUP00000049580 | ENSOCUP00000014006 | Uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin; Belongs to the uricase family. | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | 0.668 |