node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANKRD54 | LASP1 | ENSOCUP00000002459 | ENSOCUP00000026760 | ANK_REP_REGION domain-containing protein. | LIM and SH3 domain protein 1; Plays an important role in the regulation of dynamic actin- based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types (By similarity). | 0.696 |
COPS5 | LASP1 | ENSOCUP00000009878 | ENSOCUP00000026760 | COP9 signalosome subunit 5. | LIM and SH3 domain protein 1; Plays an important role in the regulation of dynamic actin- based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types (By similarity). | 0.601 |
CRKL | LASP1 | ENSOCUP00000000710 | ENSOCUP00000026760 | CRK like proto-oncogene, adaptor protein. | LIM and SH3 domain protein 1; Plays an important role in the regulation of dynamic actin- based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types (By similarity). | 0.570 |
CRKL | VASP | ENSOCUP00000000710 | ENSOCUP00000029878 | CRK like proto-oncogene, adaptor protein. | WH1 domain-containing protein. | 0.591 |
CXCR1 | LASP1 | ENSOCUP00000027727 | ENSOCUP00000026760 | C-X-C chemokine receptor type 1; Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. | LIM and SH3 domain protein 1; Plays an important role in the regulation of dynamic actin- based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types (By similarity). | 0.756 |
EZR | LASP1 | ENSOCUP00000040029 | ENSOCUP00000026760 | Ezrin; Probably involved in connections of major cytoskeletal structures to the plasma membrane (By similarity). In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis (By similarity). | LIM and SH3 domain protein 1; Plays an important role in the regulation of dynamic actin- based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types (By similarity). | 0.584 |
EZR | PALLD | ENSOCUP00000040029 | ENSOCUP00000044201 | Ezrin; Probably involved in connections of major cytoskeletal structures to the plasma membrane (By similarity). In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis (By similarity). | Palladin, cytoskeletal associated protein. | 0.573 |
EZR | VASP | ENSOCUP00000040029 | ENSOCUP00000029878 | Ezrin; Probably involved in connections of major cytoskeletal structures to the plasma membrane (By similarity). In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis (By similarity). | WH1 domain-containing protein. | 0.659 |
LASP1 | ANKRD54 | ENSOCUP00000026760 | ENSOCUP00000002459 | LIM and SH3 domain protein 1; Plays an important role in the regulation of dynamic actin- based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types (By similarity). | ANK_REP_REGION domain-containing protein. | 0.696 |
LASP1 | COPS5 | ENSOCUP00000026760 | ENSOCUP00000009878 | LIM and SH3 domain protein 1; Plays an important role in the regulation of dynamic actin- based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types (By similarity). | COP9 signalosome subunit 5. | 0.601 |
LASP1 | CRKL | ENSOCUP00000026760 | ENSOCUP00000000710 | LIM and SH3 domain protein 1; Plays an important role in the regulation of dynamic actin- based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types (By similarity). | CRK like proto-oncogene, adaptor protein. | 0.570 |
LASP1 | CXCR1 | ENSOCUP00000026760 | ENSOCUP00000027727 | LIM and SH3 domain protein 1; Plays an important role in the regulation of dynamic actin- based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types (By similarity). | C-X-C chemokine receptor type 1; Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. | 0.756 |
LASP1 | EZR | ENSOCUP00000026760 | ENSOCUP00000040029 | LIM and SH3 domain protein 1; Plays an important role in the regulation of dynamic actin- based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types (By similarity). | Ezrin; Probably involved in connections of major cytoskeletal structures to the plasma membrane (By similarity). In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis (By similarity). | 0.584 |
LASP1 | LPP | ENSOCUP00000026760 | ENSOCUP00000010109 | LIM and SH3 domain protein 1; Plays an important role in the regulation of dynamic actin- based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types (By similarity). | LIM domain containing preferred translocation partner in lipoma. | 0.760 |
LASP1 | PALLD | ENSOCUP00000026760 | ENSOCUP00000044201 | LIM and SH3 domain protein 1; Plays an important role in the regulation of dynamic actin- based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types (By similarity). | Palladin, cytoskeletal associated protein. | 0.933 |
LASP1 | TMOD3 | ENSOCUP00000026760 | ENSOCUP00000011176 | LIM and SH3 domain protein 1; Plays an important role in the regulation of dynamic actin- based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types (By similarity). | Uncharacterized protein. | 0.510 |
LASP1 | VASP | ENSOCUP00000026760 | ENSOCUP00000029878 | LIM and SH3 domain protein 1; Plays an important role in the regulation of dynamic actin- based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types (By similarity). | WH1 domain-containing protein. | 0.895 |
LASP1 | ZYX | ENSOCUP00000026760 | ENSOCUP00000018567 | LIM and SH3 domain protein 1; Plays an important role in the regulation of dynamic actin- based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types (By similarity). | Zyxin. | 0.879 |
LPP | LASP1 | ENSOCUP00000010109 | ENSOCUP00000026760 | LIM domain containing preferred translocation partner in lipoma. | LIM and SH3 domain protein 1; Plays an important role in the regulation of dynamic actin- based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types (By similarity). | 0.760 |
LPP | VASP | ENSOCUP00000010109 | ENSOCUP00000029878 | LIM domain containing preferred translocation partner in lipoma. | WH1 domain-containing protein. | 0.703 |