node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AKT3 | PPP2CA | ENSOCUP00000041212 | ENSOCUP00000013713 | Non-specific serine/threonine protein kinase. | Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGO2 to protect centromeric cohesin from separase- mediated cleavage in oocytes specifically during meiosis I. Activates RAF1 by dephosphorylating it at 'Ser-259' (By similarity). | 0.955 |
AKT3 | PPP2R1A | ENSOCUP00000041212 | ENSOCUP00000014689 | Non-specific serine/threonine protein kinase. | Protein phosphatase 2 scaffold subunit Aalpha. | 0.954 |
AKT3 | PPP2R1B | ENSOCUP00000041212 | ENSOCUP00000041612 | Non-specific serine/threonine protein kinase. | Protein phosphatase 2 scaffold subunit Abeta. | 0.951 |
AKT3 | PPP2R2A | ENSOCUP00000041212 | ENSOCUP00000035053 | Non-specific serine/threonine protein kinase. | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. | 0.910 |
AKT3 | PPP2R2B | ENSOCUP00000041212 | ENSOCUP00000028847 | Non-specific serine/threonine protein kinase. | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. | 0.910 |
AKT3 | PPP2R2D | ENSOCUP00000041212 | ENSOCUP00000020770 | Non-specific serine/threonine protein kinase. | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. | 0.903 |
IRAK1 | IRAK4 | ENSOCUP00000029957 | ENSOCUP00000031709 | Interleukin 1 receptor associated kinase 1. | Interleukin 1 receptor associated kinase 4. | 0.999 |
IRAK1 | PPP2CA | ENSOCUP00000029957 | ENSOCUP00000013713 | Interleukin 1 receptor associated kinase 1. | Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGO2 to protect centromeric cohesin from separase- mediated cleavage in oocytes specifically during meiosis I. Activates RAF1 by dephosphorylating it at 'Ser-259' (By similarity). | 0.948 |
IRAK1 | PPP2R1A | ENSOCUP00000029957 | ENSOCUP00000014689 | Interleukin 1 receptor associated kinase 1. | Protein phosphatase 2 scaffold subunit Aalpha. | 0.920 |
IRAK1 | PPP2R1B | ENSOCUP00000029957 | ENSOCUP00000041612 | Interleukin 1 receptor associated kinase 1. | Protein phosphatase 2 scaffold subunit Abeta. | 0.920 |
IRAK1 | PPP2R2A | ENSOCUP00000029957 | ENSOCUP00000035053 | Interleukin 1 receptor associated kinase 1. | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. | 0.915 |
IRAK1 | PPP2R2B | ENSOCUP00000029957 | ENSOCUP00000028847 | Interleukin 1 receptor associated kinase 1. | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. | 0.915 |
IRAK1 | PPP2R2D | ENSOCUP00000029957 | ENSOCUP00000020770 | Interleukin 1 receptor associated kinase 1. | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. | 0.900 |
IRAK4 | IRAK1 | ENSOCUP00000031709 | ENSOCUP00000029957 | Interleukin 1 receptor associated kinase 4. | Interleukin 1 receptor associated kinase 1. | 0.999 |
IRAK4 | PPP2CA | ENSOCUP00000031709 | ENSOCUP00000013713 | Interleukin 1 receptor associated kinase 4. | Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGO2 to protect centromeric cohesin from separase- mediated cleavage in oocytes specifically during meiosis I. Activates RAF1 by dephosphorylating it at 'Ser-259' (By similarity). | 0.918 |
IRAK4 | PPP2R1A | ENSOCUP00000031709 | ENSOCUP00000014689 | Interleukin 1 receptor associated kinase 4. | Protein phosphatase 2 scaffold subunit Aalpha. | 0.917 |
IRAK4 | PPP2R1B | ENSOCUP00000031709 | ENSOCUP00000041612 | Interleukin 1 receptor associated kinase 4. | Protein phosphatase 2 scaffold subunit Abeta. | 0.917 |
IRAK4 | PPP2R2A | ENSOCUP00000031709 | ENSOCUP00000035053 | Interleukin 1 receptor associated kinase 4. | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. | 0.911 |
IRAK4 | PPP2R2B | ENSOCUP00000031709 | ENSOCUP00000028847 | Interleukin 1 receptor associated kinase 4. | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. | 0.911 |
IRAK4 | PPP2R2D | ENSOCUP00000031709 | ENSOCUP00000020770 | Interleukin 1 receptor associated kinase 4. | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. | 0.900 |