STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMOC1SPARC related modular calcium binding 1. (445 aa)    
Predicted Functional Partners:
SLC38A4
Solute carrier family 38 member 4.
      
 0.753
SFMBT2
Scm like with four mbt domains 2.
      
 0.751
JADE1
Jade family PHD finger 1.
      
 0.740
CABP7
Calcium binding protein 7.
      
 0.696
SPARC
SPARC; Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity (By similarity); Belongs to the SPARC family.
   
  
 0.565
SPOCK1
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1.
      
 0.563
SALL1
Uncharacterized protein.
      
 0.562
SPARCL1
SPARC like 1.
   
  
 0.534
FSTL1
Follistatin like 1.
      
 0.495
LGI2
Leucine rich repeat LGI family member 2.
      
 0.493
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.