STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TUZN_0083Pyruvate-ferredoxin oxidoreductase and related 2-oxoacid-ferredoxin oxidoreductases gamma-alpha subunit. (557 aa)    
Predicted Functional Partners:
TUZN_0084
Pyruvate-ferredoxin oxidoreductase and related 2-oxoacid-ferredoxin oxidoreductases beta subunit.
 
 0.999
TUZN_1749
2-oxoglutarate ferredoxin oxidoreductase subunit beta.
 
 0.996
TUZN_1460
ATP-grasp domain protein.
  
 0.932
TUZN_1857
CoA-binding domain protein.
  
 0.932
TUZN_0992
2-oxoglutarate synthase, 2-oxoacid-ferredoxin oxidoreductase B subunit.
  
 0.931
TUZN_1451
Pyruvate/ketoisovalerate oxidoreductase, beta subunit.
  
 0.931
TUZN_1720
2-ketoisovalerate ferredoxin oxidoreductase, beta subunit.
  
 0.931
sucC
Succinyl-CoA synthetase, subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.930
sucD
Succinyl-CoA synthetase, subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 
 0.930
TUZN_1296
Acetolactate synthase, large subunit, biosynthetic type.
  
 
 0.925
Your Current Organism:
Thermoproteus uzoniensis
NCBI taxonomy Id: 999630
Other names: T. uzoniensis 768-20, Thermoproteus uzoniensis 768-20, Thermoproteus uzoniensis str. 768-20, Thermoproteus uzoniensis strain 768-20
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