node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANKRD20A1 | ANKRD20A2 | ENSP00000477695 | ENSP00000366826 | Ankyrin repeat domain-containing protein 20A1; Ankyrin repeat domain 20 family member A1. | Ankyrin repeat domain-containing protein 20A2. | 0.633 |
ANKRD20A1 | ANKRD20A4 | ENSP00000477695 | ENSP00000349891 | Ankyrin repeat domain-containing protein 20A1; Ankyrin repeat domain 20 family member A1. | Ankyrin repeat domain-containing protein 20A4. | 0.646 |
ANKRD20A1 | ASB15 | ENSP00000477695 | ENSP00000397655 | Ankyrin repeat domain-containing protein 20A1; Ankyrin repeat domain 20 family member A1. | Ankyrin repeat and SOCS box protein 15; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | 0.480 |
ANKRD20A1 | ASZ1 | ENSP00000477695 | ENSP00000284629 | Ankyrin repeat domain-containing protein 20A1; Ankyrin repeat domain 20 family member A1. | Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1; Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the p [...] | 0.449 |
ANKRD20A1 | CDKN2C | ENSP00000477695 | ENSP00000262662 | Ankyrin repeat domain-containing protein 20A1; Ankyrin repeat domain 20 family member A1. | Cyclin-dependent kinase 4 inhibitor C; Interacts strongly with CDK6, weakly with CDK4. Inhibits cell growth and proliferation with a correlated dependence on endogenous retinoblastoma protein RB; Belongs to the CDKN2 cyclin-dependent kinase inhibitor family. | 0.480 |
ANKRD20A1 | CDKN2D | ENSP00000477695 | ENSP00000377224 | Ankyrin repeat domain-containing protein 20A1; Ankyrin repeat domain 20 family member A1. | Cyclin-dependent kinase 4 inhibitor D; Interacts strongly with CDK4 and CDK6 and inhibits them. Belongs to the CDKN2 cyclin-dependent kinase inhibitor family. | 0.495 |
ANKRD20A1 | DCAF12L1 | ENSP00000477695 | ENSP00000360167 | Ankyrin repeat domain-containing protein 20A1; Ankyrin repeat domain 20 family member A1. | DDB1- and CUL4-associated factor 12-like protein 1; DDB1 and CUL4 associated factor 12 like 1. | 0.444 |
ANKRD20A1 | OR4M2 | ENSP00000477695 | ENSP00000483239 | Ankyrin repeat domain-containing protein 20A1; Ankyrin repeat domain 20 family member A1. | Olfactory receptor 4M2; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | 0.473 |
ANKRD20A1 | PDZRN3 | ENSP00000477695 | ENSP00000263666 | Ankyrin repeat domain-containing protein 20A1; Ankyrin repeat domain 20 family member A1. | E3 ubiquitin-protein ligase PDZRN3; E3 ubiquitin-protein ligase. Plays an important role in regulating the surface level of MUSK on myotubes. Mediates the ubiquitination of MUSK, promoting its endocytosis and lysosomal degradation. Might contribute to terminal myogenic differentiation. | 0.601 |
ANKRD20A1 | RFXANK | ENSP00000477695 | ENSP00000305071 | Ankyrin repeat domain-containing protein 20A1; Ankyrin repeat domain 20 family member A1. | DNA-binding protein RFXANK; Activates transcription from class II MHC promoters. Activation requires the activity of the MHC class II transactivator/CIITA. May regulate other genes in the cell. RFX binds the X1 box of MHC-II promoters. May also potentiate the activation of RAF1 (By similarity). | 0.481 |
ANKRD20A2 | ANKRD20A1 | ENSP00000366826 | ENSP00000477695 | Ankyrin repeat domain-containing protein 20A2. | Ankyrin repeat domain-containing protein 20A1; Ankyrin repeat domain 20 family member A1. | 0.633 |
ANKRD20A2 | ANKRD20A4 | ENSP00000366826 | ENSP00000349891 | Ankyrin repeat domain-containing protein 20A2. | Ankyrin repeat domain-containing protein 20A4. | 0.631 |
ANKRD20A2 | ASB15 | ENSP00000366826 | ENSP00000397655 | Ankyrin repeat domain-containing protein 20A2. | Ankyrin repeat and SOCS box protein 15; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | 0.476 |
ANKRD20A2 | ASZ1 | ENSP00000366826 | ENSP00000284629 | Ankyrin repeat domain-containing protein 20A2. | Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1; Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the p [...] | 0.433 |
ANKRD20A2 | CDKN2C | ENSP00000366826 | ENSP00000262662 | Ankyrin repeat domain-containing protein 20A2. | Cyclin-dependent kinase 4 inhibitor C; Interacts strongly with CDK6, weakly with CDK4. Inhibits cell growth and proliferation with a correlated dependence on endogenous retinoblastoma protein RB; Belongs to the CDKN2 cyclin-dependent kinase inhibitor family. | 0.478 |
ANKRD20A2 | CDKN2D | ENSP00000366826 | ENSP00000377224 | Ankyrin repeat domain-containing protein 20A2. | Cyclin-dependent kinase 4 inhibitor D; Interacts strongly with CDK4 and CDK6 and inhibits them. Belongs to the CDKN2 cyclin-dependent kinase inhibitor family. | 0.497 |
ANKRD20A2 | PDZRN3 | ENSP00000366826 | ENSP00000263666 | Ankyrin repeat domain-containing protein 20A2. | E3 ubiquitin-protein ligase PDZRN3; E3 ubiquitin-protein ligase. Plays an important role in regulating the surface level of MUSK on myotubes. Mediates the ubiquitination of MUSK, promoting its endocytosis and lysosomal degradation. Might contribute to terminal myogenic differentiation. | 0.617 |
ANKRD20A2 | RFXANK | ENSP00000366826 | ENSP00000305071 | Ankyrin repeat domain-containing protein 20A2. | DNA-binding protein RFXANK; Activates transcription from class II MHC promoters. Activation requires the activity of the MHC class II transactivator/CIITA. May regulate other genes in the cell. RFX binds the X1 box of MHC-II promoters. May also potentiate the activation of RAF1 (By similarity). | 0.484 |
ANKRD20A4 | ANKRD20A1 | ENSP00000349891 | ENSP00000477695 | Ankyrin repeat domain-containing protein 20A4. | Ankyrin repeat domain-containing protein 20A1; Ankyrin repeat domain 20 family member A1. | 0.646 |
ANKRD20A4 | ANKRD20A2 | ENSP00000349891 | ENSP00000366826 | Ankyrin repeat domain-containing protein 20A4. | Ankyrin repeat domain-containing protein 20A2. | 0.631 |