STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANKRD20A1Ankyrin repeat domain-containing protein 20A1; Ankyrin repeat domain 20 family member A1 (823 aa)    
Predicted Functional Partners:
CBWD7
COBW domain-containing protein 6; COBW domain containing 7; Belongs to the SIMIBI class G3E GTPase family. CobW subfamily
   
  
 0.659
FAM72C
Protein FAM72C; Family with sequence similarity 72 member C; Belongs to the FAM72 family
      
 0.603
DCAF12L1
DDB1- and CUL4-associated factor 12-like protein 1; DDB1 and CUL4 associated factor 12 like 1; WD repeat domain containing
      
 0.601
FAM72B
Protein FAM72B; Family with sequence similarity 72 member B; Belongs to the FAM72 family
      
 0.596
CBWD1
Cobw domain-containing protein 1; COBW domain containing 1
   
  
 0.566
FAM72D
Protein FAM72D; Family with sequence similarity 72 member D
      
 0.559
CARD18
Caspase recruitment domain-containing protein 18; Inhibits generation of IL-1-beta by interacting with caspase-1 and preventing its association with RIP2. Down-regulates the release of IL1B; Caspase recruitment domain containing
    
 
 0.530
CBWD3
Cobw domain-containing protein 3; COBW domain containing 3
   
  
 0.527
RABEP1
Rab GTPase-binding effector protein 1; Rab effector protein acting as linker between gamma- adaptin, RAB4A and RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Involved in KCNH1 channels trafficking to and from the cell membrane. Stimulates RABGEF1 mediated nucleotide exchange on RAB5A; Belongs to the rabaptin family
    
 
 0.435
ABHD12
Monoacylglycerol lipase ABHD12; Lysophosphatidylserine (LPS) lipase that plays a key role in the central nervous system. Represents a major LPS lipase in the brain (By similarity). May also have a 2- arachidonoylglycerol (2-AG) hydrolase activity and act as a regulator of endocannabinoid signaling pathways; Abhydrolase domain containing
   
  
 0.404
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
Server load: low (3%) [HD]