node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANKRD33B | APRT | ENSP00000296657 | ENSP00000367615 | Ankyrin repeat domain 33B. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.526 |
ANKRD33B | C19orf73 | ENSP00000296657 | ENSP00000386230 | Ankyrin repeat domain 33B. | Putative uncharacterized protein C19orf73; Chromosome 19 open reading frame 73. | 0.447 |
ANKRD33B | GART | ENSP00000296657 | ENSP00000371253 | Ankyrin repeat domain 33B. | Trifunctional purine biosynthetic protein adenosine-3; Phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase; In the central section; belongs to the AIR synthase family. | 0.446 |
ANKRD33B | GMPS | ENSP00000296657 | ENSP00000419851 | Ankyrin repeat domain 33B. | GMP synthase [glutamine-hydrolyzing]; Involved in the de novo synthesis of guanine nucleotides which are not only essential for DNA and RNA synthesis, but also provide GTP, which is involved in a number of cellular processes important for cell division. | 0.424 |
ANKRD33B | GPSM1 | ENSP00000296657 | ENSP00000392828 | Ankyrin repeat domain 33B. | G-protein-signaling modulator 1; Guanine nucleotide dissociation inhibitor (GDI) which functions as a receptor-independent activator of heterotrimeric G- protein signaling. Keeps G(i/o) alpha subunit in its GDP-bound form thus uncoupling heterotrimeric G-proteins signaling from G protein- coupled receptors. Controls spindle orientation and asymmetric cell fate of cerebral cortical progenitors. May also be involved in macroautophagy in intestinal cells. May play a role in drug addiction. Belongs to the GPSM family. | 0.422 |
ANKRD33B | HPCA | ENSP00000296657 | ENSP00000362566 | Ankyrin repeat domain 33B. | Neuron-specific calcium-binding protein hippocalcin; Calcium-binding protein that may play a role in the regulation of voltage-dependent calcium channels. May also play a role in cyclic-nucleotide-mediated signaling through the regulation of adenylate and guanylate cyclases (By similarity). Belongs to the recoverin family. | 0.624 |
ANKRD33B | NCALD | ENSP00000296657 | ENSP00000379256 | Ankyrin repeat domain 33B. | Neurocalcin-delta; May be involved in the calcium-dependent regulation of rhodopsin phosphorylation. Binds three calcium ions; Belongs to the recoverin family. | 0.631 |
ANKRD33B | POLR2F | ENSP00000296657 | ENSP00000385725 | Ankyrin repeat domain 33B. | DNA-directed RNA polymerases I, II, and III subunit RPABC2; DNA-dependent RNA polymerases catalyze the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II, and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2F/RPB6 is part of th [...] | 0.482 |
ANKRD33B | REEP6 | ENSP00000296657 | ENSP00000233596 | Ankyrin repeat domain 33B. | Receptor expression-enhancing protein 6; Required for correct function and survival of retinal photoreceptors. Required for retinal development (By similarity). In rod photoreceptors, facilitates stability and/or trafficking of guanylate cyclases and is required to maintain endoplasmic reticulum and mitochondrial homeostasis (By similarity). May play a role in clathrin-coated intracellular vesicle trafficking of proteins from the endoplasmic reticulum to the retinal rod plasma membrane (By similarity). | 0.467 |
ANKRD33B | TYMS | ENSP00000296657 | ENSP00000315644 | Ankyrin repeat domain 33B. | Thymidylate synthase; Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. | 0.426 |
APRT | ANKRD33B | ENSP00000367615 | ENSP00000296657 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Ankyrin repeat domain 33B. | 0.526 |
APRT | GART | ENSP00000367615 | ENSP00000371253 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Trifunctional purine biosynthetic protein adenosine-3; Phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase; In the central section; belongs to the AIR synthase family. | 0.879 |
APRT | GMPS | ENSP00000367615 | ENSP00000419851 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP synthase [glutamine-hydrolyzing]; Involved in the de novo synthesis of guanine nucleotides which are not only essential for DNA and RNA synthesis, but also provide GTP, which is involved in a number of cellular processes important for cell division. | 0.995 |
APRT | TYMS | ENSP00000367615 | ENSP00000315644 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Thymidylate synthase; Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. | 0.566 |
C19orf73 | ANKRD33B | ENSP00000386230 | ENSP00000296657 | Putative uncharacterized protein C19orf73; Chromosome 19 open reading frame 73. | Ankyrin repeat domain 33B. | 0.447 |
GART | ANKRD33B | ENSP00000371253 | ENSP00000296657 | Trifunctional purine biosynthetic protein adenosine-3; Phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase; In the central section; belongs to the AIR synthase family. | Ankyrin repeat domain 33B. | 0.446 |
GART | APRT | ENSP00000371253 | ENSP00000367615 | Trifunctional purine biosynthetic protein adenosine-3; Phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase; In the central section; belongs to the AIR synthase family. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.879 |
GART | GMPS | ENSP00000371253 | ENSP00000419851 | Trifunctional purine biosynthetic protein adenosine-3; Phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase; In the central section; belongs to the AIR synthase family. | GMP synthase [glutamine-hydrolyzing]; Involved in the de novo synthesis of guanine nucleotides which are not only essential for DNA and RNA synthesis, but also provide GTP, which is involved in a number of cellular processes important for cell division. | 0.937 |
GART | TYMS | ENSP00000371253 | ENSP00000315644 | Trifunctional purine biosynthetic protein adenosine-3; Phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase; In the central section; belongs to the AIR synthase family. | Thymidylate synthase; Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. | 0.895 |
GMPS | ANKRD33B | ENSP00000419851 | ENSP00000296657 | GMP synthase [glutamine-hydrolyzing]; Involved in the de novo synthesis of guanine nucleotides which are not only essential for DNA and RNA synthesis, but also provide GTP, which is involved in a number of cellular processes important for cell division. | Ankyrin repeat domain 33B. | 0.424 |