node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
APOOL | ARMC1 | ENSP00000362268 | ENSP00000276569 | MICOS complex subunit MIC27; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Specifically binds to cardiolipin (in vitro) but not to the precursor lipid phosphatidylglycerol. Plays a crucial role in crista junction formation and mitochondrial function. | Armadillo repeat containing 1. | 0.588 |
APOOL | DNAJC11 | ENSP00000362268 | ENSP00000366800 | MICOS complex subunit MIC27; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Specifically binds to cardiolipin (in vitro) but not to the precursor lipid phosphatidylglycerol. Plays a crucial role in crista junction formation and mitochondrial function. | DnaJ homolog subfamily C member 11; [Isoform 1]: Required for mitochondrial inner membrane organization. Seems to function through its association with the MICOS complex and the mitochondrial outer membrane sorting assembly machinery (SAM) complex; Belongs to the DNAJC11 family. | 0.958 |
APOOL | MICOS13 | ENSP00000362268 | ENSP00000468723 | MICOS complex subunit MIC27; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Specifically binds to cardiolipin (in vitro) but not to the precursor lipid phosphatidylglycerol. Plays a crucial role in crista junction formation and mitochondrial function. | MICOS complex subunit MIC13; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Constituent of mature MICOS complex, it is required for the formation of cristae junction (CJ) and maintenance of cristae morphology. Required for the incorporation of MICOS10/MIC10 into the MICOS complex. | 0.999 |
APOOL | MTX2 | ENSP00000362268 | ENSP00000249442 | MICOS complex subunit MIC27; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Specifically binds to cardiolipin (in vitro) but not to the precursor lipid phosphatidylglycerol. Plays a crucial role in crista junction formation and mitochondrial function. | Metaxin-2; Involved in transport of proteins into the mitochondrion. | 0.965 |
ARMC1 | APOOL | ENSP00000276569 | ENSP00000362268 | Armadillo repeat containing 1. | MICOS complex subunit MIC27; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Specifically binds to cardiolipin (in vitro) but not to the precursor lipid phosphatidylglycerol. Plays a crucial role in crista junction formation and mitochondrial function. | 0.588 |
ARMC1 | ARMC12 | ENSP00000276569 | ENSP00000288065 | Armadillo repeat containing 1. | Armadillo repeat containing 12. | 0.586 |
ARMC1 | DNAJC11 | ENSP00000276569 | ENSP00000366800 | Armadillo repeat containing 1. | DnaJ homolog subfamily C member 11; [Isoform 1]: Required for mitochondrial inner membrane organization. Seems to function through its association with the MICOS complex and the mitochondrial outer membrane sorting assembly machinery (SAM) complex; Belongs to the DNAJC11 family. | 0.804 |
ARMC1 | MAPT | ENSP00000276569 | ENSP00000340820 | Armadillo repeat containing 1. | Microtubule-associated protein tau; Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its st [...] | 0.592 |
ARMC1 | MICOS13 | ENSP00000276569 | ENSP00000468723 | Armadillo repeat containing 1. | MICOS complex subunit MIC13; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Constituent of mature MICOS complex, it is required for the formation of cristae junction (CJ) and maintenance of cristae morphology. Required for the incorporation of MICOS10/MIC10 into the MICOS complex. | 0.608 |
ARMC1 | MRPL13 | ENSP00000276569 | ENSP00000306548 | Armadillo repeat containing 1. | Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family. | 0.607 |
ARMC1 | MTFR1L | ENSP00000276569 | ENSP00000363419 | Armadillo repeat containing 1. | Mitochondrial fission regulator 1 like; Belongs to the MTFR1 family. | 0.801 |
ARMC1 | MTX2 | ENSP00000276569 | ENSP00000249442 | Armadillo repeat containing 1. | Metaxin-2; Involved in transport of proteins into the mitochondrion. | 0.630 |
ARMC1 | RMDN1 | ENSP00000276569 | ENSP00000385927 | Armadillo repeat containing 1. | Regulator of microtubule dynamics 1. | 0.645 |
ARMC1 | STX1B | ENSP00000276569 | ENSP00000215095 | Armadillo repeat containing 1. | Syntaxin-1B; Potentially involved in docking of synaptic vesicles at presynaptic active zones. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm (By similarity). | 0.570 |
ARMC12 | ARMC1 | ENSP00000288065 | ENSP00000276569 | Armadillo repeat containing 12. | Armadillo repeat containing 1. | 0.586 |
DNAJC11 | APOOL | ENSP00000366800 | ENSP00000362268 | DnaJ homolog subfamily C member 11; [Isoform 1]: Required for mitochondrial inner membrane organization. Seems to function through its association with the MICOS complex and the mitochondrial outer membrane sorting assembly machinery (SAM) complex; Belongs to the DNAJC11 family. | MICOS complex subunit MIC27; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Specifically binds to cardiolipin (in vitro) but not to the precursor lipid phosphatidylglycerol. Plays a crucial role in crista junction formation and mitochondrial function. | 0.958 |
DNAJC11 | ARMC1 | ENSP00000366800 | ENSP00000276569 | DnaJ homolog subfamily C member 11; [Isoform 1]: Required for mitochondrial inner membrane organization. Seems to function through its association with the MICOS complex and the mitochondrial outer membrane sorting assembly machinery (SAM) complex; Belongs to the DNAJC11 family. | Armadillo repeat containing 1. | 0.804 |
DNAJC11 | MICOS13 | ENSP00000366800 | ENSP00000468723 | DnaJ homolog subfamily C member 11; [Isoform 1]: Required for mitochondrial inner membrane organization. Seems to function through its association with the MICOS complex and the mitochondrial outer membrane sorting assembly machinery (SAM) complex; Belongs to the DNAJC11 family. | MICOS complex subunit MIC13; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Constituent of mature MICOS complex, it is required for the formation of cristae junction (CJ) and maintenance of cristae morphology. Required for the incorporation of MICOS10/MIC10 into the MICOS complex. | 0.926 |
DNAJC11 | MTX2 | ENSP00000366800 | ENSP00000249442 | DnaJ homolog subfamily C member 11; [Isoform 1]: Required for mitochondrial inner membrane organization. Seems to function through its association with the MICOS complex and the mitochondrial outer membrane sorting assembly machinery (SAM) complex; Belongs to the DNAJC11 family. | Metaxin-2; Involved in transport of proteins into the mitochondrion. | 0.936 |
MAPT | ARMC1 | ENSP00000340820 | ENSP00000276569 | Microtubule-associated protein tau; Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its st [...] | Armadillo repeat containing 1. | 0.592 |