node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACTR10 | ACTR1B | ENSP00000254286 | ENSP00000289228 | Actin related protein 10; Belongs to the actin family. | Beta-centractin; Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome. | 0.995 |
ACTR10 | BMERB1 | ENSP00000254286 | ENSP00000300006 | Actin related protein 10; Belongs to the actin family. | bMERB domain containing 1. | 0.596 |
ACTR10 | DCTN1 | ENSP00000254286 | ENSP00000354791 | Actin related protein 10; Belongs to the actin family. | Dynactin subunit 1; Plays a key role in dynein-mediated retrograde transport of vesicles and organelles along microtubules by recruiting and tethering dynein to microtubules. Binds to both dynein and microtubules providing a link between specific cargos, microtubules and dynein. Essential for targeting dynein to microtubule plus ends, recruiting dynein to membranous cargos and enhancing dynein processivity (the ability to move along a microtubule for a long distance without falling off the track). Can also act as a brake to slow the dynein motor during motility along the microtubule. C [...] | 0.999 |
ACTR10 | DCTN4 | ENSP00000254286 | ENSP00000414906 | Actin related protein 10; Belongs to the actin family. | Dynactin subunit 4; Could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton. | 0.999 |
ACTR10 | DCTN6 | ENSP00000254286 | ENSP00000221114 | Actin related protein 10; Belongs to the actin family. | Dynactin subunit 6; Belongs to the dynactin subunits 5/6 family. Dynactin subunit 6 subfamily. | 0.999 |
ACTR1B | ACTR10 | ENSP00000289228 | ENSP00000254286 | Beta-centractin; Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome. | Actin related protein 10; Belongs to the actin family. | 0.995 |
ACTR1B | BMERB1 | ENSP00000289228 | ENSP00000300006 | Beta-centractin; Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome. | bMERB domain containing 1. | 0.669 |
ACTR1B | DCTN1 | ENSP00000289228 | ENSP00000354791 | Beta-centractin; Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome. | Dynactin subunit 1; Plays a key role in dynein-mediated retrograde transport of vesicles and organelles along microtubules by recruiting and tethering dynein to microtubules. Binds to both dynein and microtubules providing a link between specific cargos, microtubules and dynein. Essential for targeting dynein to microtubule plus ends, recruiting dynein to membranous cargos and enhancing dynein processivity (the ability to move along a microtubule for a long distance without falling off the track). Can also act as a brake to slow the dynein motor during motility along the microtubule. C [...] | 0.997 |
ACTR1B | DCTN4 | ENSP00000289228 | ENSP00000414906 | Beta-centractin; Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome. | Dynactin subunit 4; Could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton. | 0.998 |
ACTR1B | DCTN6 | ENSP00000289228 | ENSP00000221114 | Beta-centractin; Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome. | Dynactin subunit 6; Belongs to the dynactin subunits 5/6 family. Dynactin subunit 6 subfamily. | 0.993 |
BMERB1 | ACTR10 | ENSP00000300006 | ENSP00000254286 | bMERB domain containing 1. | Actin related protein 10; Belongs to the actin family. | 0.596 |
BMERB1 | ACTR1B | ENSP00000300006 | ENSP00000289228 | bMERB domain containing 1. | Beta-centractin; Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome. | 0.669 |
BMERB1 | DCTN1 | ENSP00000300006 | ENSP00000354791 | bMERB domain containing 1. | Dynactin subunit 1; Plays a key role in dynein-mediated retrograde transport of vesicles and organelles along microtubules by recruiting and tethering dynein to microtubules. Binds to both dynein and microtubules providing a link between specific cargos, microtubules and dynein. Essential for targeting dynein to microtubule plus ends, recruiting dynein to membranous cargos and enhancing dynein processivity (the ability to move along a microtubule for a long distance without falling off the track). Can also act as a brake to slow the dynein motor during motility along the microtubule. C [...] | 0.667 |
BMERB1 | DCTN4 | ENSP00000300006 | ENSP00000414906 | bMERB domain containing 1. | Dynactin subunit 4; Could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton. | 0.669 |
BMERB1 | DCTN6 | ENSP00000300006 | ENSP00000221114 | bMERB domain containing 1. | Dynactin subunit 6; Belongs to the dynactin subunits 5/6 family. Dynactin subunit 6 subfamily. | 0.631 |
BMERB1 | FOPNL | ENSP00000300006 | ENSP00000461830 | bMERB domain containing 1. | LisH domain-containing protein FOPNL; Involved in the biogenesis of cilia. Required for the recruitment of PLK1 to centrosomes and S phase progression. | 0.718 |
BMERB1 | MARF1 | ENSP00000300006 | ENSP00000379654 | bMERB domain containing 1. | Meiosis regulator and mRNA stability factor 1; Essential regulator of oogenesis required for female meiotic progression to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Probably acts via some RNA metabolic process, equivalent to the piRNA system in males, which mediates the repression of transposable elements during meiosis by forming complexes composed of RNAs and governs the methylation and subsequent repression of transposons. Also required to protect from DNA double-strand breaks (By similarity). | 0.647 |
BMERB1 | MPV17L | ENSP00000300006 | ENSP00000379669 | bMERB domain containing 1. | Mpv17-like protein; Isoform 1 participates in reactive oxygen species metabolism by up- or down-regulation of the genes of antioxidant enzymes. Belongs to the peroxisomal membrane protein PXMP2/4 family. | 0.585 |
BMERB1 | MPV17L-2 | ENSP00000300006 | ENSP00000454340 | bMERB domain containing 1. | Mpv17-like protein; Belongs to the peroxisomal membrane protein PXMP2/4 family. | 0.554 |
BMERB1 | SDHB | ENSP00000300006 | ENSP00000364649 | bMERB domain containing 1. | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). | 0.791 |