node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CA11 | CA12 | ENSP00000084798 | ENSP00000178638 | Carbonic anhydrase-related protein 11; Does not have a catalytic activity. | Carbonic anhydrase 12; Reversible hydration of carbon dioxide. Belongs to the alpha-carbonic anhydrase family. | 0.411 |
CA11 | CA4 | ENSP00000084798 | ENSP00000300900 | Carbonic anhydrase-related protein 11; Does not have a catalytic activity. | Carbonic anhydrase 4; Reversible hydration of carbon dioxide. May stimulate the sodium/bicarbonate transporter activity of SLC4A4 that acts in pH homeostasis. It is essential for acid overload removal from the retina and retina epithelium, and acid release in the choriocapillaris in the choroid; Belongs to the alpha-carbonic anhydrase family. | 0.426 |
CA11 | EVPLL | ENSP00000084798 | ENSP00000382086 | Carbonic anhydrase-related protein 11; Does not have a catalytic activity. | Envoplakin-like protein; Envoplakin like; Belongs to the plakin or cytolinker family. | 0.451 |
CA11 | GRWD1 | ENSP00000084798 | ENSP00000253237 | Carbonic anhydrase-related protein 11; Does not have a catalytic activity. | Glutamate-rich WD repeat-containing protein 1; Histone binding-protein that regulates chromatin dynamics and minichromosome maintenance (MCM) loading at replication origins, possibly by promoting chromatin openness. | 0.451 |
CA11 | ITPR1 | ENSP00000084798 | ENSP00000306253 | Carbonic anhydrase-related protein 11; Does not have a catalytic activity. | Inositol 1,4,5-trisphosphate receptor type 1; Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5- trisphosphate. Involved in the regulation of epithelial secretion of electrolytes and fluid through the interaction with AHCYL1 (By similarity). Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity). | 0.464 |
CA11 | RPF2 | ENSP00000084798 | ENSP00000402338 | Carbonic anhydrase-related protein 11; Does not have a catalytic activity. | Ribosome production factor 2 homolog; Involved in ribosomal large subunit assembly. May regulate the localization of the 5S RNP/5S ribonucleoprotein particle to the nucleolus. | 0.561 |
CA11 | RPL5 | ENSP00000084798 | ENSP00000359345 | Carbonic anhydrase-related protein 11; Does not have a catalytic activity. | 60S ribosomal protein L5; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...] | 0.478 |
CA11 | RRS1 | ENSP00000084798 | ENSP00000322396 | Carbonic anhydrase-related protein 11; Does not have a catalytic activity. | Ribosome biogenesis regulatory protein homolog; Involved in ribosomal large subunit assembly. May regulate the localization of the 5S RNP/5S ribonucleoprotein particle to the nucleolus; Belongs to the RRS1 family. | 0.473 |
CA11 | SLFNL1 | ENSP00000084798 | ENSP00000352299 | Carbonic anhydrase-related protein 11; Does not have a catalytic activity. | Schlafen-like protein 1; Schlafen like 1. | 0.463 |
CA11 | UTP18 | ENSP00000084798 | ENSP00000225298 | Carbonic anhydrase-related protein 11; Does not have a catalytic activity. | U3 small nucleolar RNA-associated protein 18 homolog; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the WD repeat UTP18 family. | 0.438 |
CA12 | CA11 | ENSP00000178638 | ENSP00000084798 | Carbonic anhydrase 12; Reversible hydration of carbon dioxide. Belongs to the alpha-carbonic anhydrase family. | Carbonic anhydrase-related protein 11; Does not have a catalytic activity. | 0.411 |
CA12 | CA4 | ENSP00000178638 | ENSP00000300900 | Carbonic anhydrase 12; Reversible hydration of carbon dioxide. Belongs to the alpha-carbonic anhydrase family. | Carbonic anhydrase 4; Reversible hydration of carbon dioxide. May stimulate the sodium/bicarbonate transporter activity of SLC4A4 that acts in pH homeostasis. It is essential for acid overload removal from the retina and retina epithelium, and acid release in the choriocapillaris in the choroid; Belongs to the alpha-carbonic anhydrase family. | 0.640 |
CA12 | GRWD1 | ENSP00000178638 | ENSP00000253237 | Carbonic anhydrase 12; Reversible hydration of carbon dioxide. Belongs to the alpha-carbonic anhydrase family. | Glutamate-rich WD repeat-containing protein 1; Histone binding-protein that regulates chromatin dynamics and minichromosome maintenance (MCM) loading at replication origins, possibly by promoting chromatin openness. | 0.451 |
CA12 | RPF2 | ENSP00000178638 | ENSP00000402338 | Carbonic anhydrase 12; Reversible hydration of carbon dioxide. Belongs to the alpha-carbonic anhydrase family. | Ribosome production factor 2 homolog; Involved in ribosomal large subunit assembly. May regulate the localization of the 5S RNP/5S ribonucleoprotein particle to the nucleolus. | 0.561 |
CA12 | RPL5 | ENSP00000178638 | ENSP00000359345 | Carbonic anhydrase 12; Reversible hydration of carbon dioxide. Belongs to the alpha-carbonic anhydrase family. | 60S ribosomal protein L5; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...] | 0.478 |
CA12 | RRS1 | ENSP00000178638 | ENSP00000322396 | Carbonic anhydrase 12; Reversible hydration of carbon dioxide. Belongs to the alpha-carbonic anhydrase family. | Ribosome biogenesis regulatory protein homolog; Involved in ribosomal large subunit assembly. May regulate the localization of the 5S RNP/5S ribonucleoprotein particle to the nucleolus; Belongs to the RRS1 family. | 0.473 |
CA4 | CA11 | ENSP00000300900 | ENSP00000084798 | Carbonic anhydrase 4; Reversible hydration of carbon dioxide. May stimulate the sodium/bicarbonate transporter activity of SLC4A4 that acts in pH homeostasis. It is essential for acid overload removal from the retina and retina epithelium, and acid release in the choriocapillaris in the choroid; Belongs to the alpha-carbonic anhydrase family. | Carbonic anhydrase-related protein 11; Does not have a catalytic activity. | 0.426 |
CA4 | CA12 | ENSP00000300900 | ENSP00000178638 | Carbonic anhydrase 4; Reversible hydration of carbon dioxide. May stimulate the sodium/bicarbonate transporter activity of SLC4A4 that acts in pH homeostasis. It is essential for acid overload removal from the retina and retina epithelium, and acid release in the choriocapillaris in the choroid; Belongs to the alpha-carbonic anhydrase family. | Carbonic anhydrase 12; Reversible hydration of carbon dioxide. Belongs to the alpha-carbonic anhydrase family. | 0.640 |
CA4 | GRWD1 | ENSP00000300900 | ENSP00000253237 | Carbonic anhydrase 4; Reversible hydration of carbon dioxide. May stimulate the sodium/bicarbonate transporter activity of SLC4A4 that acts in pH homeostasis. It is essential for acid overload removal from the retina and retina epithelium, and acid release in the choriocapillaris in the choroid; Belongs to the alpha-carbonic anhydrase family. | Glutamate-rich WD repeat-containing protein 1; Histone binding-protein that regulates chromatin dynamics and minichromosome maintenance (MCM) loading at replication origins, possibly by promoting chromatin openness. | 0.451 |
CA4 | RPF2 | ENSP00000300900 | ENSP00000402338 | Carbonic anhydrase 4; Reversible hydration of carbon dioxide. May stimulate the sodium/bicarbonate transporter activity of SLC4A4 that acts in pH homeostasis. It is essential for acid overload removal from the retina and retina epithelium, and acid release in the choriocapillaris in the choroid; Belongs to the alpha-carbonic anhydrase family. | Ribosome production factor 2 homolog; Involved in ribosomal large subunit assembly. May regulate the localization of the 5S RNP/5S ribonucleoprotein particle to the nucleolus. | 0.561 |