CCDC124 protein (human) - STRING interaction network

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CCDC124

Coiled-coil domain-containing protein 124; Required for proper progression of late cytokinetic stages. Belongs to the CCDC124 family. (223 aa)

Predicted Functional Partners:

FAU

0.952

RPS5

0.924

RPS19

0.922

RPL5

0.918

RPS15

0.918

RPL23A

0.917

RPL11

0.917

RACK1

0.916

RPL8

0.910

RPS7

0.908

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCDC124	FAU	ENSP00000471455	ENSP00000431822	Coiled-coil domain-containing protein 124; Required for proper progression of late cytokinetic stages. Belongs to the CCDC124 family.	Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion.	0.952
CCDC124	RACK1	ENSP00000471455	ENSP00000426909	Coiled-coil domain-containing protein 124; Required for proper progression of late cytokinetic stages. Belongs to the CCDC124 family.	Receptor of activated protein C kinase 1, N-terminally processed; Scaffolding protein involved in the recruitment, assembly and/or regulation of a variety of signaling molecules. Interacts with a wide variety of proteins and plays a role in many cellular processes. Component of the 40S ribosomal subunit involved in translational repression. Involved in the initiation of the ribosome quality control (RQC), a pathway that takes place when a ribosome has stalled during translation, by promoting ubiquitination of a subset of 40S ribosomal subunits. Binds to and stabilizes activated protein [...]	0.916
CCDC124	RPL11	ENSP00000471455	ENSP00000496250	Coiled-coil domain-containing protein 124; Required for proper progression of late cytokinetic stages. Belongs to the CCDC124 family.	60S ribosomal protein L11; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...]	0.917
CCDC124	RPL23A	ENSP00000471455	ENSP00000389103	Coiled-coil domain-containing protein 124; Required for proper progression of late cytokinetic stages. Belongs to the CCDC124 family.	60S ribosomal protein L23a; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Binds a specific region on the 26S rRNA. May promote p53/TP53 degradation possibly through the stimulation of MDM2-mediated TP53 polyubiquitination ; Belongs to the universal ribosomal protein uL23 family.	0.917
CCDC124	RPL5	ENSP00000471455	ENSP00000359345	Coiled-coil domain-containing protein 124; Required for proper progression of late cytokinetic stages. Belongs to the CCDC124 family.	60S ribosomal protein L5; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...]	0.918
CCDC124	RPL8	ENSP00000471455	ENSP00000262584	Coiled-coil domain-containing protein 124; Required for proper progression of late cytokinetic stages. Belongs to the CCDC124 family.	60S ribosomal protein L8; Component of the large ribosomal subunit.	0.910
CCDC124	RPS15	ENSP00000471455	ENSP00000466010	Coiled-coil domain-containing protein 124; Required for proper progression of late cytokinetic stages. Belongs to the CCDC124 family.	Ribosomal protein S15.	0.918
CCDC124	RPS19	ENSP00000471455	ENSP00000470972	Coiled-coil domain-containing protein 124; Required for proper progression of late cytokinetic stages. Belongs to the CCDC124 family.	40S ribosomal protein S19; Required for pre-rRNA processing and maturation of 40S ribosomal subunits; Belongs to the eukaryotic ribosomal protein eS19 family.	0.922
CCDC124	RPS5	ENSP00000471455	ENSP00000472985	Coiled-coil domain-containing protein 124; Required for proper progression of late cytokinetic stages. Belongs to the CCDC124 family.	40S ribosomal protein S5, N-terminally processed; Ribosomal protein S5; Belongs to the universal ribosomal protein uS7 family.	0.924
CCDC124	RPS7	ENSP00000471455	ENSP00000495273	Coiled-coil domain-containing protein 124; Required for proper progression of late cytokinetic stages. Belongs to the CCDC124 family.	40S ribosomal protein S7; Required for rRNA maturation.	0.908
FAU	CCDC124	ENSP00000431822	ENSP00000471455	Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion.	Coiled-coil domain-containing protein 124; Required for proper progression of late cytokinetic stages. Belongs to the CCDC124 family.	0.952
FAU	RACK1	ENSP00000431822	ENSP00000426909	Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion.	Receptor of activated protein C kinase 1, N-terminally processed; Scaffolding protein involved in the recruitment, assembly and/or regulation of a variety of signaling molecules. Interacts with a wide variety of proteins and plays a role in many cellular processes. Component of the 40S ribosomal subunit involved in translational repression. Involved in the initiation of the ribosome quality control (RQC), a pathway that takes place when a ribosome has stalled during translation, by promoting ubiquitination of a subset of 40S ribosomal subunits. Binds to and stabilizes activated protein [...]	0.999
FAU	RPL11	ENSP00000431822	ENSP00000496250	Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion.	60S ribosomal protein L11; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...]	0.999
FAU	RPL23A	ENSP00000431822	ENSP00000389103	Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion.	60S ribosomal protein L23a; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Binds a specific region on the 26S rRNA. May promote p53/TP53 degradation possibly through the stimulation of MDM2-mediated TP53 polyubiquitination ; Belongs to the universal ribosomal protein uL23 family.	0.999
FAU	RPL5	ENSP00000431822	ENSP00000359345	Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion.	60S ribosomal protein L5; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...]	0.999
FAU	RPL8	ENSP00000431822	ENSP00000262584	Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion.	60S ribosomal protein L8; Component of the large ribosomal subunit.	0.999
FAU	RPS15	ENSP00000431822	ENSP00000466010	Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion.	Ribosomal protein S15.	0.999
FAU	RPS19	ENSP00000431822	ENSP00000470972	Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion.	40S ribosomal protein S19; Required for pre-rRNA processing and maturation of 40S ribosomal subunits; Belongs to the eukaryotic ribosomal protein eS19 family.	0.999
FAU	RPS5	ENSP00000431822	ENSP00000472985	Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion.	40S ribosomal protein S5, N-terminally processed; Ribosomal protein S5; Belongs to the universal ribosomal protein uS7 family.	0.999
FAU	RPS7	ENSP00000431822	ENSP00000495273	Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion.	40S ribosomal protein S7; Required for rRNA maturation.	0.999