node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C11orf88 | CCDC33 | ENSP00000333845 | ENSP00000381795 | UPF0722 protein C11orf88. | Coiled-coil domain containing 33. | 0.550 |
CCDC33 | C11orf88 | ENSP00000381795 | ENSP00000333845 | Coiled-coil domain containing 33. | UPF0722 protein C11orf88. | 0.550 |
CCDC33 | CCDC96 | ENSP00000381795 | ENSP00000309285 | Coiled-coil domain containing 33. | Coiled-coil domain containing 96. | 0.473 |
CCDC33 | CFAP157 | ENSP00000381795 | ENSP00000362392 | Coiled-coil domain containing 33. | Cilia- and flagella-associated protein 157; Specifically required during spermatogenesis for flagellum morphogenesis and sperm motility. May be required to suppress the formation of supernumerary axonemes and ensure a correct ultrastructure; Belongs to the CFAP157 family. | 0.497 |
CCDC33 | DRC7 | ENSP00000381795 | ENSP00000353942 | Coiled-coil domain containing 33. | Dynein regulatory complex subunit 7; Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Involved in the regulation of flagellar motility. | 0.579 |
CCDC33 | FBF1 | ENSP00000381795 | ENSP00000490726 | Coiled-coil domain containing 33. | Fas-binding factor 1; Keratin-binding protein required for epithelial cell polarization. Involved in apical junction complex (AJC) assembly via its interaction with PARD3. Required for ciliogenesis. | 0.617 |
CCDC33 | ISLR2 | ENSP00000381795 | ENSP00000355402 | Coiled-coil domain containing 33. | Immunoglobulin superfamily containing leucine-rich repeat protein 2; Required for axon extension during neural development. | 0.482 |
CCDC33 | RIBC2 | ENSP00000381795 | ENSP00000483356 | Coiled-coil domain containing 33. | RIB43A domain with coiled-coils 2. | 0.509 |
CCDC33 | SMAD3 | ENSP00000381795 | ENSP00000332973 | Coiled-coil domain containing 33. | Mothers against decapentaplegic homolog 3; Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD3/SMAD4 complex, activates transcription. Also can form a SMAD3/SMAD4/JUN/FOS complex at the AP- 1/SMAD site to regulate TGF-beta-mediated transcription. Has an inhibitory effect on wound healing probably by modulating both growth and m [...] | 0.473 |
CCDC33 | SMARCB1 | ENSP00000381795 | ENSP00000340883 | Coiled-coil domain containing 33. | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Core component of the BAF (hSWI/SNF) complex. This ATP- dependent chromatin-remodeling complex plays important roles in cell proliferation and differentiation, in cellular antiviral activities and inhibition of tumor formation. The BAF complex is able to create a stable, altered form of chromatin that constrains fewer negative supercoils than normal. This change in supercoiling would be due to the conversion of up to one-half of the nucleosomes on polynucleosomal arrays into asymmetric struct [...] | 0.593 |
CCDC33 | UBL7 | ENSP00000381795 | ENSP00000457703 | Coiled-coil domain containing 33. | Ubiquitin-like protein 7; Ubiquitin like 7. | 0.661 |
CCDC96 | CCDC33 | ENSP00000309285 | ENSP00000381795 | Coiled-coil domain containing 96. | Coiled-coil domain containing 33. | 0.473 |
CCDC96 | DRC7 | ENSP00000309285 | ENSP00000353942 | Coiled-coil domain containing 96. | Dynein regulatory complex subunit 7; Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Involved in the regulation of flagellar motility. | 0.474 |
CFAP157 | CCDC33 | ENSP00000362392 | ENSP00000381795 | Cilia- and flagella-associated protein 157; Specifically required during spermatogenesis for flagellum morphogenesis and sperm motility. May be required to suppress the formation of supernumerary axonemes and ensure a correct ultrastructure; Belongs to the CFAP157 family. | Coiled-coil domain containing 33. | 0.497 |
CFAP157 | DRC7 | ENSP00000362392 | ENSP00000353942 | Cilia- and flagella-associated protein 157; Specifically required during spermatogenesis for flagellum morphogenesis and sperm motility. May be required to suppress the formation of supernumerary axonemes and ensure a correct ultrastructure; Belongs to the CFAP157 family. | Dynein regulatory complex subunit 7; Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Involved in the regulation of flagellar motility. | 0.588 |
DRC7 | CCDC33 | ENSP00000353942 | ENSP00000381795 | Dynein regulatory complex subunit 7; Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Involved in the regulation of flagellar motility. | Coiled-coil domain containing 33. | 0.579 |
DRC7 | CCDC96 | ENSP00000353942 | ENSP00000309285 | Dynein regulatory complex subunit 7; Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Involved in the regulation of flagellar motility. | Coiled-coil domain containing 96. | 0.474 |
DRC7 | CFAP157 | ENSP00000353942 | ENSP00000362392 | Dynein regulatory complex subunit 7; Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Involved in the regulation of flagellar motility. | Cilia- and flagella-associated protein 157; Specifically required during spermatogenesis for flagellum morphogenesis and sperm motility. May be required to suppress the formation of supernumerary axonemes and ensure a correct ultrastructure; Belongs to the CFAP157 family. | 0.588 |
DRC7 | RIBC2 | ENSP00000353942 | ENSP00000483356 | Dynein regulatory complex subunit 7; Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Involved in the regulation of flagellar motility. | RIB43A domain with coiled-coils 2. | 0.575 |
FBF1 | CCDC33 | ENSP00000490726 | ENSP00000381795 | Fas-binding factor 1; Keratin-binding protein required for epithelial cell polarization. Involved in apical junction complex (AJC) assembly via its interaction with PARD3. Required for ciliogenesis. | Coiled-coil domain containing 33. | 0.617 |