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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CHCHD1Coiled-coil-helix-coiled-coil-helix domain-containing protein 1; Mitochondrial coiled-coil-helix-coiled-coil-helix domain containing proteins (118 aa)    
Predicted Functional Partners:
AURKAIP1
Aurora kinase A-interacting protein; May act as a negative regulator of Aurora-A kinase, by down-regulation through proteasome-dependent degradation
   
 0.991
MRPS24
28S ribosomal protein S24, mitochondrial; Mitochondrial ribosomal protein S24; Belongs to the universal ribosomal protein uS3 family
   
 0.988
MRPS33
28S ribosomal protein S33, mitochondrial; Mitochondrial ribosomal protein S33; Belongs to the mitochondrion-specific ribosomal protein mS33 family
   
  0.988
PTCD3
Pentatricopeptide repeat domain-containing protein 3, mitochondrial; Mitochondrial RNA-binding protein that has a role in mitochondrial translation
   
 0.985
DAP3
28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family
   
 0.982
MRPS16
28S ribosomal protein S16, mitochondrial; Mitochondrial ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family
   
  0.981
MRPS7
28S ribosomal protein S7, mitochondrial; Mitochondrial ribosomal protein S7; Belongs to the universal ribosomal protein uS7 family
   
 0.980
MRPS31
28S ribosomal protein S31, mitochondrial; Mitochondrial ribosomal protein S31
   
 0.979
MRPS15
28S ribosomal protein S15, mitochondrial; Mitochondrial ribosomal protein S15; Belongs to the universal ribosomal protein uS15 family
   
 0.979
MRPS5
28S ribosomal protein S5, mitochondrial; Belongs to the universal ribosomal protein uS5 family
   
 0.978
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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