node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DEFB114 | DEFB118 | ENSP00000312702 | ENSP00000253381 | Beta-defensin 114; Has a salt-sensitive antimicrobial activity against Gram- negative bacteria, including E.coli, Gram-positive, including S.aureus, and fungi, including C.albicans. Binds to and neutralizes bacterial lipopolysaccharides (LPS), abolishing TNF production by macrophages challenged with LPS. Rescues the LPS-induced reduction of sperm motility in vitro and may protect from LPS-induced lethality. | Beta-defensin 118; Has antibacterial activity. | 0.859 |
DEFB114 | DEFB119 | ENSP00000312702 | ENSP00000365492 | Beta-defensin 114; Has a salt-sensitive antimicrobial activity against Gram- negative bacteria, including E.coli, Gram-positive, including S.aureus, and fungi, including C.albicans. Binds to and neutralizes bacterial lipopolysaccharides (LPS), abolishing TNF production by macrophages challenged with LPS. Rescues the LPS-induced reduction of sperm motility in vitro and may protect from LPS-induced lethality. | Defensin beta 119. | 0.648 |
DEFB114 | DEFB121 | ENSP00000312702 | ENSP00000417128 | Beta-defensin 114; Has a salt-sensitive antimicrobial activity against Gram- negative bacteria, including E.coli, Gram-positive, including S.aureus, and fungi, including C.albicans. Binds to and neutralizes bacterial lipopolysaccharides (LPS), abolishing TNF production by macrophages challenged with LPS. Rescues the LPS-induced reduction of sperm motility in vitro and may protect from LPS-induced lethality. | Beta-defensin 121; Has antibacterial activity; Belongs to the beta-defensin family. | 0.550 |
DEFB114 | DEFB124 | ENSP00000312702 | ENSP00000326309 | Beta-defensin 114; Has a salt-sensitive antimicrobial activity against Gram- negative bacteria, including E.coli, Gram-positive, including S.aureus, and fungi, including C.albicans. Binds to and neutralizes bacterial lipopolysaccharides (LPS), abolishing TNF production by macrophages challenged with LPS. Rescues the LPS-induced reduction of sperm motility in vitro and may protect from LPS-induced lethality. | Beta-defensin 124; Has antibacterial activity; Belongs to the beta-defensin family. | 0.801 |
DEFB114 | DEFB125 | ENSP00000312702 | ENSP00000371847 | Beta-defensin 114; Has a salt-sensitive antimicrobial activity against Gram- negative bacteria, including E.coli, Gram-positive, including S.aureus, and fungi, including C.albicans. Binds to and neutralizes bacterial lipopolysaccharides (LPS), abolishing TNF production by macrophages challenged with LPS. Rescues the LPS-induced reduction of sperm motility in vitro and may protect from LPS-induced lethality. | Beta-defensin 125; Has antibacterial activity; Belongs to the beta-defensin family. | 0.837 |
DEFB114 | DEFB127 | ENSP00000312702 | ENSP00000371825 | Beta-defensin 114; Has a salt-sensitive antimicrobial activity against Gram- negative bacteria, including E.coli, Gram-positive, including S.aureus, and fungi, including C.albicans. Binds to and neutralizes bacterial lipopolysaccharides (LPS), abolishing TNF production by macrophages challenged with LPS. Rescues the LPS-induced reduction of sperm motility in vitro and may protect from LPS-induced lethality. | Beta-defensin 127; Has antibacterial activity. | 0.869 |
DEFB114 | DEFB128 | ENSP00000312702 | ENSP00000335382 | Beta-defensin 114; Has a salt-sensitive antimicrobial activity against Gram- negative bacteria, including E.coli, Gram-positive, including S.aureus, and fungi, including C.albicans. Binds to and neutralizes bacterial lipopolysaccharides (LPS), abolishing TNF production by macrophages challenged with LPS. Rescues the LPS-induced reduction of sperm motility in vitro and may protect from LPS-induced lethality. | Beta-defensin 128; Has antibacterial activity; Belongs to the beta-defensin family. | 0.806 |
DEFB114 | DEFB130A | ENSP00000312702 | ENSP00000382951 | Beta-defensin 114; Has a salt-sensitive antimicrobial activity against Gram- negative bacteria, including E.coli, Gram-positive, including S.aureus, and fungi, including C.albicans. Binds to and neutralizes bacterial lipopolysaccharides (LPS), abolishing TNF production by macrophages challenged with LPS. Rescues the LPS-induced reduction of sperm motility in vitro and may protect from LPS-induced lethality. | Beta-defensin 130A; Antimicrobial host-defense peptide. Has an antiplasmodial activity. | 0.561 |
DEFB114 | DEFB134 | ENSP00000312702 | ENSP00000435010 | Beta-defensin 114; Has a salt-sensitive antimicrobial activity against Gram- negative bacteria, including E.coli, Gram-positive, including S.aureus, and fungi, including C.albicans. Binds to and neutralizes bacterial lipopolysaccharides (LPS), abolishing TNF production by macrophages challenged with LPS. Rescues the LPS-induced reduction of sperm motility in vitro and may protect from LPS-induced lethality. | Beta-defensin 134; Has antibacterial activity; Belongs to the beta-defensin family. | 0.830 |
DEFB114 | DEFB135 | ENSP00000312702 | ENSP00000371643 | Beta-defensin 114; Has a salt-sensitive antimicrobial activity against Gram- negative bacteria, including E.coli, Gram-positive, including S.aureus, and fungi, including C.albicans. Binds to and neutralizes bacterial lipopolysaccharides (LPS), abolishing TNF production by macrophages challenged with LPS. Rescues the LPS-induced reduction of sperm motility in vitro and may protect from LPS-induced lethality. | Beta-defensin 135; Has antibacterial activity; Belongs to the beta-defensin family. | 0.823 |
DEFB118 | DEFB114 | ENSP00000253381 | ENSP00000312702 | Beta-defensin 118; Has antibacterial activity. | Beta-defensin 114; Has a salt-sensitive antimicrobial activity against Gram- negative bacteria, including E.coli, Gram-positive, including S.aureus, and fungi, including C.albicans. Binds to and neutralizes bacterial lipopolysaccharides (LPS), abolishing TNF production by macrophages challenged with LPS. Rescues the LPS-induced reduction of sperm motility in vitro and may protect from LPS-induced lethality. | 0.859 |
DEFB118 | DEFB119 | ENSP00000253381 | ENSP00000365492 | Beta-defensin 118; Has antibacterial activity. | Defensin beta 119. | 0.849 |
DEFB118 | DEFB121 | ENSP00000253381 | ENSP00000417128 | Beta-defensin 118; Has antibacterial activity. | Beta-defensin 121; Has antibacterial activity; Belongs to the beta-defensin family. | 0.590 |
DEFB118 | DEFB124 | ENSP00000253381 | ENSP00000326309 | Beta-defensin 118; Has antibacterial activity. | Beta-defensin 124; Has antibacterial activity; Belongs to the beta-defensin family. | 0.666 |
DEFB118 | DEFB125 | ENSP00000253381 | ENSP00000371847 | Beta-defensin 118; Has antibacterial activity. | Beta-defensin 125; Has antibacterial activity; Belongs to the beta-defensin family. | 0.769 |
DEFB118 | DEFB127 | ENSP00000253381 | ENSP00000371825 | Beta-defensin 118; Has antibacterial activity. | Beta-defensin 127; Has antibacterial activity. | 0.843 |
DEFB118 | DEFB128 | ENSP00000253381 | ENSP00000335382 | Beta-defensin 118; Has antibacterial activity. | Beta-defensin 128; Has antibacterial activity; Belongs to the beta-defensin family. | 0.643 |
DEFB118 | DEFB130A | ENSP00000253381 | ENSP00000382951 | Beta-defensin 118; Has antibacterial activity. | Beta-defensin 130A; Antimicrobial host-defense peptide. Has an antiplasmodial activity. | 0.719 |
DEFB118 | DEFB134 | ENSP00000253381 | ENSP00000435010 | Beta-defensin 118; Has antibacterial activity. | Beta-defensin 134; Has antibacterial activity; Belongs to the beta-defensin family. | 0.583 |
DEFB118 | DEFB135 | ENSP00000253381 | ENSP00000371643 | Beta-defensin 118; Has antibacterial activity. | Beta-defensin 135; Has antibacterial activity; Belongs to the beta-defensin family. | 0.712 |