STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DPY19L1Probable C-mannosyltransferase DPY19L1; Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins. (675 aa)    
Predicted Functional Partners:
EFCAB11
EF-hand calcium-binding domain-containing protein 11; EF-hand calcium binding domain 11.
   
  
 0.590
TSR3
Ribosome biogenesis protein TSR3 homolog; Probable pre-rRNA processing protein involved in ribosome biogenesis.
      
 0.540
NPSR1
Neuropeptide S receptor; G-protein coupled receptor for neuropeptide S (NPS). Promotes mobilization of intracellular Ca(2+) stores. Inhibits cell growth in response to NPS binding. Involved in pathogenesis of asthma and other IgE- mediated diseases.
   
  
 0.527
MANBAL
Protein MANBAL; Mannosidase beta like; Belongs to the UPF0239 family.
      
 0.490
UNC5A
Netrin receptor UNC5A; Receptor for netrin required for axon guidance. Functions in the netrin signaling pathway and promotes neurite outgrowth in response to NTN1. Mediates axon repulsion of neuronal growth cones in the developing nervous system in response to netrin. Axon repulsion in growth cones may be mediated by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand.
    
 
 0.475
TSR1
Pre-rRNA-processing protein TSR1 homolog; Required during maturation of the 40S ribosomal subunit in the nucleolus; Belongs to the TRAFAC class translation factor GTPase superfamily. Bms1-like GTPase family. TSR1 subfamily.
   
  
 0.463
CASC1
Protein CASC1.
   
    0.461
TSR2
Pre-rRNA-processing protein TSR2 homolog; May be involved in 20S pre-rRNA processing.
      
 0.460
OR5I1
Olfactory receptor 5I1; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.448
CDRT15
CMT1A duplicated region transcript 15.
    
   0.440
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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