node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EFCAB13 | EFCAB3 | ENSP00000332111 | ENSP00000403932 | EF-hand calcium-binding domain-containing protein 13; EF-hand calcium binding domain 13. | EF-hand calcium-binding domain-containing protein 3; EF-hand calcium binding domain 3. | 0.492 |
EFCAB13 | MYO1E | ENSP00000332111 | ENSP00000288235 | EF-hand calcium-binding domain-containing protein 13; EF-hand calcium binding domain 13. | Unconventional myosin-Ie; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails bind to membranous compartments, which are then moved relative to actin filaments. Binds to membranes containing anionic phospholipids via its tail domain. Required for normal morphology of the glomerular basement membrane, normal development of foot processes by kidney podocytes and normal kidney function. In dendritic cells, may control the movement of class II-containing cytoplasmic vesicles along the actin cyto [...] | 0.491 |
EFCAB13 | MYO1F | ENSP00000332111 | ENSP00000494550 | EF-hand calcium-binding domain-containing protein 13; EF-hand calcium binding domain 13. | Unconventional myosin-If; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments (By similarity). Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.491 |
EFCAB13 | MYO6 | ENSP00000332111 | ENSP00000358994 | EF-hand calcium-binding domain-containing protein 13; EF-hand calcium binding domain 13. | Unconventional myosin-VI; Myosins are actin-based motor molecules with ATPase activity (By similarity). Unconventional myosins serve in intracellular movements (By similarity). Myosin 6 is a reverse-direction motor protein that moves towards the minus-end of actin filaments. Has slow rate of actin-activated ADP release due to weak ATP binding (By similarity). Functions in a variety of intracellular processes such as vesicular membrane trafficking and cell migration (By similarity). Required for the structural integrity of the Golgi apparatus via the p53-dependent pro-survival pathway. [...] | 0.490 |
EFCAB3 | EFCAB13 | ENSP00000403932 | ENSP00000332111 | EF-hand calcium-binding domain-containing protein 3; EF-hand calcium binding domain 3. | EF-hand calcium-binding domain-containing protein 13; EF-hand calcium binding domain 13. | 0.492 |
EFCAB3 | INSL6 | ENSP00000403932 | ENSP00000371054 | EF-hand calcium-binding domain-containing protein 3; EF-hand calcium binding domain 3. | Insulin-like peptide INSL6 A chain; May have a role in sperm development and fertilization. | 0.533 |
EFCAB3 | IQCF2 | ENSP00000403932 | ENSP00000329904 | EF-hand calcium-binding domain-containing protein 3; EF-hand calcium binding domain 3. | IQ motif containing F2. | 0.674 |
EFCAB3 | MARCHF10 | ENSP00000403932 | ENSP00000463080 | EF-hand calcium-binding domain-containing protein 3; EF-hand calcium binding domain 3. | Probable E3 ubiquitin-protein ligase MARCHF10; E3 ubiquitin-protein ligase (Probable). E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. | 0.583 |
EFCAB3 | METTL2A | ENSP00000403932 | ENSP00000309610 | EF-hand calcium-binding domain-containing protein 3; EF-hand calcium binding domain 3. | tRNA N(3)-methylcytidine methyltransferase METTL2A; S-adenosyl-L-methionine-dependent methyltransferase that mediates N(3)-methylcytidine modification of residue 32 of the tRNA anticodon loop of tRNA(Thr)(UGU) and tRNA(Arg)(CCU). Belongs to the methyltransferase superfamily. METL family. | 0.670 |
EFCAB3 | METTL2B | ENSP00000403932 | ENSP00000262432 | EF-hand calcium-binding domain-containing protein 3; EF-hand calcium binding domain 3. | tRNA N(3)-methylcytidine methyltransferase METTL2B; S-adenosyl-L-methionine-dependent methyltransferase that mediates N(3)-methylcytidine modification of residue 32 of the tRNA anticodon loop of tRNA(Thr)(UGU) and tRNA(Arg)(CCU). Belongs to the methyltransferase superfamily. METL family. | 0.627 |
EFCAB3 | MYO1E | ENSP00000403932 | ENSP00000288235 | EF-hand calcium-binding domain-containing protein 3; EF-hand calcium binding domain 3. | Unconventional myosin-Ie; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails bind to membranous compartments, which are then moved relative to actin filaments. Binds to membranes containing anionic phospholipids via its tail domain. Required for normal morphology of the glomerular basement membrane, normal development of foot processes by kidney podocytes and normal kidney function. In dendritic cells, may control the movement of class II-containing cytoplasmic vesicles along the actin cyto [...] | 0.491 |
EFCAB3 | MYO1F | ENSP00000403932 | ENSP00000494550 | EF-hand calcium-binding domain-containing protein 3; EF-hand calcium binding domain 3. | Unconventional myosin-If; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments (By similarity). Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.491 |
EFCAB3 | MYO6 | ENSP00000403932 | ENSP00000358994 | EF-hand calcium-binding domain-containing protein 3; EF-hand calcium binding domain 3. | Unconventional myosin-VI; Myosins are actin-based motor molecules with ATPase activity (By similarity). Unconventional myosins serve in intracellular movements (By similarity). Myosin 6 is a reverse-direction motor protein that moves towards the minus-end of actin filaments. Has slow rate of actin-activated ADP release due to weak ATP binding (By similarity). Functions in a variety of intracellular processes such as vesicular membrane trafficking and cell migration (By similarity). Required for the structural integrity of the Golgi apparatus via the p53-dependent pro-survival pathway. [...] | 0.490 |
EFCAB3 | SMLR1 | ENSP00000403932 | ENSP00000456026 | EF-hand calcium-binding domain-containing protein 3; EF-hand calcium binding domain 3. | Small leucine rich protein 1. | 0.598 |
INSL6 | EFCAB3 | ENSP00000371054 | ENSP00000403932 | Insulin-like peptide INSL6 A chain; May have a role in sperm development and fertilization. | EF-hand calcium-binding domain-containing protein 3; EF-hand calcium binding domain 3. | 0.533 |
IQCF2 | EFCAB3 | ENSP00000329904 | ENSP00000403932 | IQ motif containing F2. | EF-hand calcium-binding domain-containing protein 3; EF-hand calcium binding domain 3. | 0.674 |
MARCHF10 | EFCAB3 | ENSP00000463080 | ENSP00000403932 | Probable E3 ubiquitin-protein ligase MARCHF10; E3 ubiquitin-protein ligase (Probable). E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. | EF-hand calcium-binding domain-containing protein 3; EF-hand calcium binding domain 3. | 0.583 |
MARCHF10 | METTL2A | ENSP00000463080 | ENSP00000309610 | Probable E3 ubiquitin-protein ligase MARCHF10; E3 ubiquitin-protein ligase (Probable). E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. | tRNA N(3)-methylcytidine methyltransferase METTL2A; S-adenosyl-L-methionine-dependent methyltransferase that mediates N(3)-methylcytidine modification of residue 32 of the tRNA anticodon loop of tRNA(Thr)(UGU) and tRNA(Arg)(CCU). Belongs to the methyltransferase superfamily. METL family. | 0.452 |
MARCHF10 | METTL2B | ENSP00000463080 | ENSP00000262432 | Probable E3 ubiquitin-protein ligase MARCHF10; E3 ubiquitin-protein ligase (Probable). E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. | tRNA N(3)-methylcytidine methyltransferase METTL2B; S-adenosyl-L-methionine-dependent methyltransferase that mediates N(3)-methylcytidine modification of residue 32 of the tRNA anticodon loop of tRNA(Thr)(UGU) and tRNA(Arg)(CCU). Belongs to the methyltransferase superfamily. METL family. | 0.412 |
METTL2A | EFCAB3 | ENSP00000309610 | ENSP00000403932 | tRNA N(3)-methylcytidine methyltransferase METTL2A; S-adenosyl-L-methionine-dependent methyltransferase that mediates N(3)-methylcytidine modification of residue 32 of the tRNA anticodon loop of tRNA(Thr)(UGU) and tRNA(Arg)(CCU). Belongs to the methyltransferase superfamily. METL family. | EF-hand calcium-binding domain-containing protein 3; EF-hand calcium binding domain 3. | 0.670 |