STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EIF5AL1Eukaryotic translation initiation factor 5A-1-like; mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation [...] (154 aa)    
Predicted Functional Partners:
RPL15
Large subunit ribosomal protein l15e; Ribosomal protein L15
   
 
 0.936
RPL38
Large subunit ribosomal protein l38e; Ribosomal protein L38; Belongs to the eukaryotic ribosomal protein eL38 family
   
   0.916
EEF1G
Eukaryotic translation elongation factor 1 gamma; Elongation factor 1-gamma; Probably plays a role in anchoring the complex to other cellular components
   
 
 0.916
RPS28
Small subunit ribosomal protein s28e; Ribosomal protein S28; Belongs to the eukaryotic ribosomal protein eS28 family
   
 
 0.906
RPS17
Small subunit ribosomal protein s17e; Ribosomal protein S17
  
 
 0.901
RPL9
Large subunit ribosomal protein l9e; L ribosomal proteins
   
 
 0.895
RPS13
Small subunit ribosomal protein s13e; Ribosomal protein S13
  
 
 0.892
RPS15
Small subunit ribosomal protein s15e; Ribosomal protein S15
   
 
 0.873
DHPS
Deoxyhypusine synthase; Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue
  
 
 0.872
RPS18
40S ribosomal protein S18; Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA; S ribosomal proteins
  
 
 0.872
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
Server load: low (4%) [HD]