node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
COX4I1 | COX4I2 | ENSP00000457513 | ENSP00000365243 | Cytochrome c oxidase subunit 4 isoform 1, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives tran [...] | Cytochrome c oxidase subunit 4 isoform 2, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives tran [...] | 0.909 |
COX4I1 | EMC4 | ENSP00000457513 | ENSP00000267750 | Cytochrome c oxidase subunit 4 isoform 1, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives tran [...] | ER membrane protein complex subunit 4; May mediate anti-apoptotic activity. | 0.404 |
COX4I1 | EMC8 | ENSP00000457513 | ENSP00000253457 | Cytochrome c oxidase subunit 4 isoform 1, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives tran [...] | ER membrane protein complex subunit 8. | 0.965 |
COX4I2 | COX4I1 | ENSP00000365243 | ENSP00000457513 | Cytochrome c oxidase subunit 4 isoform 2, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives tran [...] | Cytochrome c oxidase subunit 4 isoform 1, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives tran [...] | 0.909 |
COX4I2 | EMC8 | ENSP00000365243 | ENSP00000253457 | Cytochrome c oxidase subunit 4 isoform 2, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives tran [...] | ER membrane protein complex subunit 8. | 0.949 |
EMC1 | EMC10 | ENSP00000420608 | ENSP00000334037 | ER membrane protein complex subunit 1; Belongs to the EMC1 family. | ER membrane protein complex subunit 10; Promotes angiogenesis and tissue repair in the heart after myocardial infarction. Stimulates cardiac endothelial cell migration and outgrowth via the activation of p38 MAPK, PAK and MAPK2 signaling pathways. | 0.999 |
EMC1 | EMC2 | ENSP00000420608 | ENSP00000220853 | ER membrane protein complex subunit 1; Belongs to the EMC1 family. | ER membrane protein complex subunit 2. | 0.999 |
EMC1 | EMC3 | ENSP00000420608 | ENSP00000245046 | ER membrane protein complex subunit 1; Belongs to the EMC1 family. | ER membrane protein complex subunit 3. | 0.999 |
EMC1 | EMC4 | ENSP00000420608 | ENSP00000267750 | ER membrane protein complex subunit 1; Belongs to the EMC1 family. | ER membrane protein complex subunit 4; May mediate anti-apoptotic activity. | 0.999 |
EMC1 | EMC6 | ENSP00000420608 | ENSP00000380322 | ER membrane protein complex subunit 1; Belongs to the EMC1 family. | ER membrane protein complex subunit 6; Belongs to the EMC6 family. | 0.999 |
EMC1 | EMC7 | ENSP00000420608 | ENSP00000256545 | ER membrane protein complex subunit 1; Belongs to the EMC1 family. | ER membrane protein complex subunit 7; Belongs to the EMC7 family. | 0.999 |
EMC1 | EMC8 | ENSP00000420608 | ENSP00000253457 | ER membrane protein complex subunit 1; Belongs to the EMC1 family. | ER membrane protein complex subunit 8. | 0.999 |
EMC1 | MMGT1 | ENSP00000420608 | ENSP00000306220 | ER membrane protein complex subunit 1; Belongs to the EMC1 family. | Membrane magnesium transporter 1; Mediates Mg(2+) transport; Belongs to the membrane magnesium transporter (TC 1.A.67) family. | 0.999 |
EMC10 | EMC1 | ENSP00000334037 | ENSP00000420608 | ER membrane protein complex subunit 10; Promotes angiogenesis and tissue repair in the heart after myocardial infarction. Stimulates cardiac endothelial cell migration and outgrowth via the activation of p38 MAPK, PAK and MAPK2 signaling pathways. | ER membrane protein complex subunit 1; Belongs to the EMC1 family. | 0.999 |
EMC10 | EMC2 | ENSP00000334037 | ENSP00000220853 | ER membrane protein complex subunit 10; Promotes angiogenesis and tissue repair in the heart after myocardial infarction. Stimulates cardiac endothelial cell migration and outgrowth via the activation of p38 MAPK, PAK and MAPK2 signaling pathways. | ER membrane protein complex subunit 2. | 0.999 |
EMC10 | EMC3 | ENSP00000334037 | ENSP00000245046 | ER membrane protein complex subunit 10; Promotes angiogenesis and tissue repair in the heart after myocardial infarction. Stimulates cardiac endothelial cell migration and outgrowth via the activation of p38 MAPK, PAK and MAPK2 signaling pathways. | ER membrane protein complex subunit 3. | 0.999 |
EMC10 | EMC4 | ENSP00000334037 | ENSP00000267750 | ER membrane protein complex subunit 10; Promotes angiogenesis and tissue repair in the heart after myocardial infarction. Stimulates cardiac endothelial cell migration and outgrowth via the activation of p38 MAPK, PAK and MAPK2 signaling pathways. | ER membrane protein complex subunit 4; May mediate anti-apoptotic activity. | 0.999 |
EMC10 | EMC6 | ENSP00000334037 | ENSP00000380322 | ER membrane protein complex subunit 10; Promotes angiogenesis and tissue repair in the heart after myocardial infarction. Stimulates cardiac endothelial cell migration and outgrowth via the activation of p38 MAPK, PAK and MAPK2 signaling pathways. | ER membrane protein complex subunit 6; Belongs to the EMC6 family. | 0.998 |
EMC10 | EMC7 | ENSP00000334037 | ENSP00000256545 | ER membrane protein complex subunit 10; Promotes angiogenesis and tissue repair in the heart after myocardial infarction. Stimulates cardiac endothelial cell migration and outgrowth via the activation of p38 MAPK, PAK and MAPK2 signaling pathways. | ER membrane protein complex subunit 7; Belongs to the EMC7 family. | 0.999 |
EMC10 | EMC8 | ENSP00000334037 | ENSP00000253457 | ER membrane protein complex subunit 10; Promotes angiogenesis and tissue repair in the heart after myocardial infarction. Stimulates cardiac endothelial cell migration and outgrowth via the activation of p38 MAPK, PAK and MAPK2 signaling pathways. | ER membrane protein complex subunit 8. | 0.998 |