Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CHCHD7 | FAM110B | ENSP00000306425 | ENSP00000355204 | Coiled-coil-helix-coiled-coil-helix domain containing 7; Belongs to the CHCHD7 family. | Protein FAM110B; May be involved in tumor progression. | 0.613 |
| CHCHD7 | SDR16C5 | ENSP00000306425 | ENSP00000431010 | Coiled-coil-helix-coiled-coil-helix domain containing 7; Belongs to the CHCHD7 family. | Epidermal retinol dehydrogenase 2; Oxidoreductase with strong preference for NAD. Active in both the oxidative and reductive directions. Oxidizes all-trans-retinol in all-trans-retinaldehyde. No activity was detected with 11-cis-retinol or 11-cis-retinaldehyde as substrates with either NAD(+)/NADH or NADP(+)/NADPH; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.723 |
| CHCHD7 | TMEM68 | ENSP00000306425 | ENSP00000395204 | Coiled-coil-helix-coiled-coil-helix domain containing 7; Belongs to the CHCHD7 family. | Transmembrane protein 68. | 0.694 |
| CHCHD7 | UBXN2B | ENSP00000306425 | ENSP00000382507 | Coiled-coil-helix-coiled-coil-helix domain containing 7; Belongs to the CHCHD7 family. | UBX domain-containing protein 2B; Adapter protein required for Golgi and endoplasmic reticulum biogenesis. Involved in Golgi and endoplasmic reticulum maintenance during interphase and in their reassembly at the end of mitosis. The complex formed with VCP has membrane fusion activity; membrane fusion activity requires USO1-GOLGA2 tethering and BET1L. VCPIP1 is also required, but not its deubiquitinating activity. Together with NSFL1C/p47, regulates the centrosomal levels of kinase AURKA/Aurora A during mitotic progression by promoting AURKA removal from centrosomes in prophase. Also, r [...] | 0.470 |
| CHCHD7 | XKR4 | ENSP00000306425 | ENSP00000328326 | Coiled-coil-helix-coiled-coil-helix domain containing 7; Belongs to the CHCHD7 family. | XK-related protein 4; XK related 4. | 0.623 |
| CSNK1D | CSNK1E | ENSP00000381531 | ENSP00000380044 | Casein kinase I isoform delta; Essential serine/threonine-protein kinase that regulates diverse cellular growth and survival processes including Wnt signaling, DNA repair and circadian rhythms. It can phosphorylate a large number of proteins. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Phosphorylates connexin-43/GJA1, MAP1A, SNAPIN, MAPT/TAU, TOP2A, DCK, HIF1A, EIF6, p53/TP53, DVL2, DVL3, ESR1, AIB1/NCOA3, DNMT1, PKD2, YAP1, PER1 and PER2. Central component of the circadian clock. In balance with PP1, dete [...] | Casein kinase I isoform epsilon; Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates DVL1 and DVL2. Central component of the circadian clock. In balance with PP1, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. Controls PER1 and PER2 nuclear transport and degradation. Inhibits cytokine-induced granuloytic differentiation. | 0.989 |
| CSNK1D | FAM110B | ENSP00000381531 | ENSP00000355204 | Casein kinase I isoform delta; Essential serine/threonine-protein kinase that regulates diverse cellular growth and survival processes including Wnt signaling, DNA repair and circadian rhythms. It can phosphorylate a large number of proteins. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Phosphorylates connexin-43/GJA1, MAP1A, SNAPIN, MAPT/TAU, TOP2A, DCK, HIF1A, EIF6, p53/TP53, DVL2, DVL3, ESR1, AIB1/NCOA3, DNMT1, PKD2, YAP1, PER1 and PER2. Central component of the circadian clock. In balance with PP1, dete [...] | Protein FAM110B; May be involved in tumor progression. | 0.683 |
| CSNK1E | CSNK1D | ENSP00000380044 | ENSP00000381531 | Casein kinase I isoform epsilon; Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates DVL1 and DVL2. Central component of the circadian clock. In balance with PP1, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. Controls PER1 and PER2 nuclear transport and degradation. Inhibits cytokine-induced granuloytic differentiation. | Casein kinase I isoform delta; Essential serine/threonine-protein kinase that regulates diverse cellular growth and survival processes including Wnt signaling, DNA repair and circadian rhythms. It can phosphorylate a large number of proteins. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Phosphorylates connexin-43/GJA1, MAP1A, SNAPIN, MAPT/TAU, TOP2A, DCK, HIF1A, EIF6, p53/TP53, DVL2, DVL3, ESR1, AIB1/NCOA3, DNMT1, PKD2, YAP1, PER1 and PER2. Central component of the circadian clock. In balance with PP1, dete [...] | 0.989 |
| CSNK1E | FAM110B | ENSP00000380044 | ENSP00000355204 | Casein kinase I isoform epsilon; Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates DVL1 and DVL2. Central component of the circadian clock. In balance with PP1, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. Controls PER1 and PER2 nuclear transport and degradation. Inhibits cytokine-induced granuloytic differentiation. | Protein FAM110B; May be involved in tumor progression. | 0.628 |
| CSPP1 | FAM110B | ENSP00000262210 | ENSP00000355204 | Centrosome and spindle pole-associated protein 1; May play a role in cell-cycle-dependent microtubule organization. | Protein FAM110B; May be involved in tumor progression. | 0.948 |
| FAM110B | CHCHD7 | ENSP00000355204 | ENSP00000306425 | Protein FAM110B; May be involved in tumor progression. | Coiled-coil-helix-coiled-coil-helix domain containing 7; Belongs to the CHCHD7 family. | 0.613 |
| FAM110B | CSNK1D | ENSP00000355204 | ENSP00000381531 | Protein FAM110B; May be involved in tumor progression. | Casein kinase I isoform delta; Essential serine/threonine-protein kinase that regulates diverse cellular growth and survival processes including Wnt signaling, DNA repair and circadian rhythms. It can phosphorylate a large number of proteins. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Phosphorylates connexin-43/GJA1, MAP1A, SNAPIN, MAPT/TAU, TOP2A, DCK, HIF1A, EIF6, p53/TP53, DVL2, DVL3, ESR1, AIB1/NCOA3, DNMT1, PKD2, YAP1, PER1 and PER2. Central component of the circadian clock. In balance with PP1, dete [...] | 0.683 |
| FAM110B | CSNK1E | ENSP00000355204 | ENSP00000380044 | Protein FAM110B; May be involved in tumor progression. | Casein kinase I isoform epsilon; Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates DVL1 and DVL2. Central component of the circadian clock. In balance with PP1, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. Controls PER1 and PER2 nuclear transport and degradation. Inhibits cytokine-induced granuloytic differentiation. | 0.628 |
| FAM110B | CSPP1 | ENSP00000355204 | ENSP00000262210 | Protein FAM110B; May be involved in tumor progression. | Centrosome and spindle pole-associated protein 1; May play a role in cell-cycle-dependent microtubule organization. | 0.948 |
| FAM110B | GIN1 | ENSP00000355204 | ENSP00000381970 | Protein FAM110B; May be involved in tumor progression. | Gypsy retrotransposon integrase 1. | 0.549 |
| FAM110B | NSMAF | ENSP00000355204 | ENSP00000411012 | Protein FAM110B; May be involved in tumor progression. | Protein FAN; Couples the p55 TNF-receptor (TNF-R55 / TNFR1) to neutral sphingomyelinase (N-SMASE). Specifically binds to the N-smase activation domain of TNF-R55. May regulate ceramide production by N- SMASE. | 0.594 |
| FAM110B | SDR16C5 | ENSP00000355204 | ENSP00000431010 | Protein FAM110B; May be involved in tumor progression. | Epidermal retinol dehydrogenase 2; Oxidoreductase with strong preference for NAD. Active in both the oxidative and reductive directions. Oxidizes all-trans-retinol in all-trans-retinaldehyde. No activity was detected with 11-cis-retinol or 11-cis-retinaldehyde as substrates with either NAD(+)/NADH or NADP(+)/NADPH; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.588 |
| FAM110B | TMEM68 | ENSP00000355204 | ENSP00000395204 | Protein FAM110B; May be involved in tumor progression. | Transmembrane protein 68. | 0.624 |
| FAM110B | UBXN2B | ENSP00000355204 | ENSP00000382507 | Protein FAM110B; May be involved in tumor progression. | UBX domain-containing protein 2B; Adapter protein required for Golgi and endoplasmic reticulum biogenesis. Involved in Golgi and endoplasmic reticulum maintenance during interphase and in their reassembly at the end of mitosis. The complex formed with VCP has membrane fusion activity; membrane fusion activity requires USO1-GOLGA2 tethering and BET1L. VCPIP1 is also required, but not its deubiquitinating activity. Together with NSFL1C/p47, regulates the centrosomal levels of kinase AURKA/Aurora A during mitotic progression by promoting AURKA removal from centrosomes in prophase. Also, r [...] | 0.681 |
| FAM110B | XKR4 | ENSP00000355204 | ENSP00000328326 | Protein FAM110B; May be involved in tumor progression. | XK-related protein 4; XK related 4. | 0.598 |
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