STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAM178BProtein FAM178B; Family with sequence similarity 178 member B. (679 aa)    
Predicted Functional Partners:
FAHD2B
Fumarylacetoacetate hydrolase domain-containing protein 2B; May have hydrolase activity.
      
 0.696
ITPRIPL1
Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1; ITPRIP like 1.
   
  
 0.600
ANKRD39
Ankyrin repeat domain 39; Belongs to the ANKRD39 family.
      
 0.590
ANKRD36
Ankyrin repeat domain-containing protein 36A; Ankyrin repeat domain 36.
      
 0.570
CNNM3
Metal transporter CNNM3; Probable metal transporter; Belongs to the ACDP family.
   
  
 0.545
LCA5L
Lebercilin-like protein; Lebercilin LCA5 like.
   
  
 0.531
CATSPERB
Cation channel sperm-associated protein subunit beta; Probably involved in sperm cell hyperactivation via its association with CATSPER1. Sperm cell hyperactivation is needed for sperm motility which is essential late in the preparation of sperm for fertilization.
      
 0.528
CCDC60
Coiled-coil domain containing 60.
   
  
 0.526
FER1L5
Fer-1-like protein 5; Plays a role in myoblast fusion; probable mediator of endocytic recycling for membrane trafficking events during myotube formation.
   
  
 0.507
ANKRD36C
Ankyrin repeat domain 36C.
      
 0.480
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.