node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AMER3 | FAM171B | ENSP00000392700 | ENSP00000304108 | APC membrane recruitment protein 3; Regulator of the canonical Wnt signaling pathway. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane (By similarity). | Protein FAM171B; Family with sequence similarity 171 member B; Belongs to the FAM171 family. | 0.414 |
AMER3 | FAM189A1 | ENSP00000392700 | ENSP00000261275 | APC membrane recruitment protein 3; Regulator of the canonical Wnt signaling pathway. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane (By similarity). | Protein FAM189A1; Family with sequence similarity 189 member A1; Belongs to the FAM189 family. | 0.434 |
AMER3 | TMEM145 | ENSP00000392700 | ENSP00000301204 | APC membrane recruitment protein 3; Regulator of the canonical Wnt signaling pathway. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane (By similarity). | Transmembrane protein 145. | 0.477 |
AMER3 | TMEM179 | ENSP00000392700 | ENSP00000450958 | APC membrane recruitment protein 3; Regulator of the canonical Wnt signaling pathway. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane (By similarity). | Transmembrane protein 179; Belongs to the TMEM179 family. | 0.450 |
AMER3 | TMEM88B | ENSP00000392700 | ENSP00000455099 | APC membrane recruitment protein 3; Regulator of the canonical Wnt signaling pathway. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane (By similarity). | Transmembrane protein 88B. | 0.431 |
APBA2 | FAM189A1 | ENSP00000453293 | ENSP00000261275 | Amyloid-beta A4 precursor protein-binding family A member 2; Putative function in synaptic vesicle exocytosis by binding to STXBP1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the amyloid-beta precursor protein (APP) and hence formation of APP-beta. | Protein FAM189A1; Family with sequence similarity 189 member A1; Belongs to the FAM189 family. | 0.474 |
FAM171B | AMER3 | ENSP00000304108 | ENSP00000392700 | Protein FAM171B; Family with sequence similarity 171 member B; Belongs to the FAM171 family. | APC membrane recruitment protein 3; Regulator of the canonical Wnt signaling pathway. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane (By similarity). | 0.414 |
FAM171B | FAM189A1 | ENSP00000304108 | ENSP00000261275 | Protein FAM171B; Family with sequence similarity 171 member B; Belongs to the FAM171 family. | Protein FAM189A1; Family with sequence similarity 189 member A1; Belongs to the FAM189 family. | 0.449 |
FAM171B | FAM81A | ENSP00000304108 | ENSP00000288228 | Protein FAM171B; Family with sequence similarity 171 member B; Belongs to the FAM171 family. | Protein FAM81A; Family with sequence similarity 81 member A; Belongs to the FAM81 family. | 0.400 |
FAM171B | TMEM145 | ENSP00000304108 | ENSP00000301204 | Protein FAM171B; Family with sequence similarity 171 member B; Belongs to the FAM171 family. | Transmembrane protein 145. | 0.440 |
FAM171B | TMEM179 | ENSP00000304108 | ENSP00000450958 | Protein FAM171B; Family with sequence similarity 171 member B; Belongs to the FAM171 family. | Transmembrane protein 179; Belongs to the TMEM179 family. | 0.429 |
FAM171B | TMEM59L | ENSP00000304108 | ENSP00000470879 | Protein FAM171B; Family with sequence similarity 171 member B; Belongs to the FAM171 family. | Transmembrane protein 59-like; Modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of APP. Inhibits APP transport to the cell surface and further shedding. | 0.407 |
FAM171B | TMEM88B | ENSP00000304108 | ENSP00000455099 | Protein FAM171B; Family with sequence similarity 171 member B; Belongs to the FAM171 family. | Transmembrane protein 88B. | 0.464 |
FAM189A1 | AMER3 | ENSP00000261275 | ENSP00000392700 | Protein FAM189A1; Family with sequence similarity 189 member A1; Belongs to the FAM189 family. | APC membrane recruitment protein 3; Regulator of the canonical Wnt signaling pathway. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane (By similarity). | 0.434 |
FAM189A1 | APBA2 | ENSP00000261275 | ENSP00000453293 | Protein FAM189A1; Family with sequence similarity 189 member A1; Belongs to the FAM189 family. | Amyloid-beta A4 precursor protein-binding family A member 2; Putative function in synaptic vesicle exocytosis by binding to STXBP1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the amyloid-beta precursor protein (APP) and hence formation of APP-beta. | 0.474 |
FAM189A1 | FAM171B | ENSP00000261275 | ENSP00000304108 | Protein FAM189A1; Family with sequence similarity 189 member A1; Belongs to the FAM189 family. | Protein FAM171B; Family with sequence similarity 171 member B; Belongs to the FAM171 family. | 0.449 |
FAM189A1 | FAM81A | ENSP00000261275 | ENSP00000288228 | Protein FAM189A1; Family with sequence similarity 189 member A1; Belongs to the FAM189 family. | Protein FAM81A; Family with sequence similarity 81 member A; Belongs to the FAM81 family. | 0.451 |
FAM189A1 | IQCA1L | ENSP00000261275 | ENSP00000482119 | Protein FAM189A1; Family with sequence similarity 189 member A1; Belongs to the FAM189 family. | IQ and AAA domain-containing protein 1-like; IQ motif containing with AAA domain 1 like; Belongs to the AAA ATPase family. | 0.605 |
FAM189A1 | STUM | ENSP00000261275 | ENSP00000355752 | Protein FAM189A1; Family with sequence similarity 189 member A1; Belongs to the FAM189 family. | Protein stum homolog; Stum, mechanosensory transduction mediator homolog. | 0.454 |
FAM189A1 | TMEM145 | ENSP00000261275 | ENSP00000301204 | Protein FAM189A1; Family with sequence similarity 189 member A1; Belongs to the FAM189 family. | Transmembrane protein 145. | 0.460 |