STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAM25AProtein FAM25A; Family with sequence similarity 25 member A; Belongs to the FAM25 family. (89 aa)    
Predicted Functional Partners:
ANTXRL
Anthrax toxin receptor-like; ANTXR like.
      
 0.594
CRCT1
Cysteine rich C-terminal 1.
   
  
 0.560
NUTM2D
NUT family member 2D; Belongs to the NUT family.
      
 0.528
AGAP9
ArfGAP with GTPase domain, ankyrin repeat and PH domain 9.
      
 0.519
AGAP6
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 6; Putative GTPase-activating protein; Belongs to the centaurin gamma-like family.
      
 0.480
NPIPB9
Nuclear pore complex interacting protein family member B9; Belongs to the NPIP family.
      
 0.479
MMRN2
Multimerin-2; Inhibits endothelial cells motility and acts as a negative regulator of angiogenesis; it downregulates KDR activation by binding VEGFA.
      
 0.467
MTRNR2L10
Humanin-like 10; Plays a role as a neuroprotective and antiapoptotic factor. Belongs to the humanin family.
      
 0.446
SPRR1A
Cornifin-A; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane.
   
  
 0.421
RGPD6
RANBP2 like and GRIP domain containing 6.
      
 0.400
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.