node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CDRT15L2 | DIPK1A | ENSP00000382000 | ENSP00000359333 | CMT1A duplicated region transcript 15 like 2. | Divergent protein kinase domain 1A. | 0.506 |
DIPK1A | CDRT15L2 | ENSP00000359333 | ENSP00000382000 | Divergent protein kinase domain 1A. | CMT1A duplicated region transcript 15 like 2. | 0.506 |
DIPK1A | DIPK1B | ENSP00000359333 | ENSP00000360757 | Divergent protein kinase domain 1A. | Divergent protein kinase domain 1B; Belongs to the DIPK family. | 0.450 |
DIPK1A | DIPK2A | ENSP00000359333 | ENSP00000320081 | Divergent protein kinase domain 1A. | Divergent protein kinase domain 2A; May play a role in cardiomyocyte proliferation through paracrine signaling and activation of the PPI3K-AKT-CDK7 signaling cascade; Belongs to the DIPK family. | 0.571 |
DIPK1A | DIPK2B | ENSP00000359333 | ENSP00000381086 | Divergent protein kinase domain 1A. | Divergent protein kinase domain 2B. | 0.657 |
DIPK1A | EVI5 | ENSP00000359333 | ENSP00000440826 | Divergent protein kinase domain 1A. | Ecotropic viral integration site 5 protein homolog; Functions as a regulator of cell cycle progression by stabilizing the FBXO5 protein and promoting cyclin-A accumulation during interphase. May play a role in cytokinesis. | 0.530 |
DIPK1A | FAM136A | ENSP00000359333 | ENSP00000397269 | Divergent protein kinase domain 1A. | Protein FAM136A; Family with sequence similarity 136 member A. | 0.596 |
DIPK1A | PKDCC | ENSP00000359333 | ENSP00000294964 | Divergent protein kinase domain 1A. | Extracellular tyrosine-protein kinase PKDCC; Secreted tyrosine-protein kinase that mediates phosphorylation of extracellular proteins and endogenous proteins in the secretory pathway, which is essential for patterning at organogenesis stages. Mediates phosphorylation of MMP1, MMP13, MMP14, MMP19 and ERP29. Probably plays a role in platelets: rapidly and quantitatively secreted from platelets in response to stimulation of platelet degranulation. May also have serine/threonine protein kinase activity. Required for longitudinal bone growth through regulation of chondrocyte differentiation [...] | 0.518 |
DIPK1A | POMK | ENSP00000359333 | ENSP00000331258 | Divergent protein kinase domain 1A. | Protein O-mannose kinase; Protein O-mannose kinase that specifically mediates phosphorylation at the 6-position of an O-mannose of the trisaccharide (N-acetylgalactosamine (GalNAc)-beta-1,3-N-acetylglucosamine (GlcNAc)- beta-1,4-mannose) to generate phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-1,3-N-acetylglucosamine-beta-1,4- (phosphate-6-)mannose). Phosphorylated O-mannosyl trisaccharide is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Only [...] | 0.446 |
DIPK1A | PPP6R2 | ENSP00000359333 | ENSP00000478417 | Divergent protein kinase domain 1A. | Serine/threonine-protein phosphatase 6 regulatory subunit 2; Regulatory subunit of protein phosphatase 6 (PP6). May function as a scaffolding PP6 subunit. Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha; Belongs to the SAPS family. | 0.493 |
DIPK1A | SEL1L3 | ENSP00000359333 | ENSP00000382767 | Divergent protein kinase domain 1A. | Protein sel-1 homolog 3; SEL1L family member 3. | 0.440 |
DIPK1B | DIPK1A | ENSP00000360757 | ENSP00000359333 | Divergent protein kinase domain 1B; Belongs to the DIPK family. | Divergent protein kinase domain 1A. | 0.450 |
DIPK1B | DIPK2B | ENSP00000360757 | ENSP00000381086 | Divergent protein kinase domain 1B; Belongs to the DIPK family. | Divergent protein kinase domain 2B. | 0.573 |
DIPK2A | DIPK1A | ENSP00000320081 | ENSP00000359333 | Divergent protein kinase domain 2A; May play a role in cardiomyocyte proliferation through paracrine signaling and activation of the PPI3K-AKT-CDK7 signaling cascade; Belongs to the DIPK family. | Divergent protein kinase domain 1A. | 0.571 |
DIPK2A | PKDCC | ENSP00000320081 | ENSP00000294964 | Divergent protein kinase domain 2A; May play a role in cardiomyocyte proliferation through paracrine signaling and activation of the PPI3K-AKT-CDK7 signaling cascade; Belongs to the DIPK family. | Extracellular tyrosine-protein kinase PKDCC; Secreted tyrosine-protein kinase that mediates phosphorylation of extracellular proteins and endogenous proteins in the secretory pathway, which is essential for patterning at organogenesis stages. Mediates phosphorylation of MMP1, MMP13, MMP14, MMP19 and ERP29. Probably plays a role in platelets: rapidly and quantitatively secreted from platelets in response to stimulation of platelet degranulation. May also have serine/threonine protein kinase activity. Required for longitudinal bone growth through regulation of chondrocyte differentiation [...] | 0.405 |
DIPK2B | DIPK1A | ENSP00000381086 | ENSP00000359333 | Divergent protein kinase domain 2B. | Divergent protein kinase domain 1A. | 0.657 |
DIPK2B | DIPK1B | ENSP00000381086 | ENSP00000360757 | Divergent protein kinase domain 2B. | Divergent protein kinase domain 1B; Belongs to the DIPK family. | 0.573 |
DIPK2B | PKDCC | ENSP00000381086 | ENSP00000294964 | Divergent protein kinase domain 2B. | Extracellular tyrosine-protein kinase PKDCC; Secreted tyrosine-protein kinase that mediates phosphorylation of extracellular proteins and endogenous proteins in the secretory pathway, which is essential for patterning at organogenesis stages. Mediates phosphorylation of MMP1, MMP13, MMP14, MMP19 and ERP29. Probably plays a role in platelets: rapidly and quantitatively secreted from platelets in response to stimulation of platelet degranulation. May also have serine/threonine protein kinase activity. Required for longitudinal bone growth through regulation of chondrocyte differentiation [...] | 0.480 |
DIPK2B | POMK | ENSP00000381086 | ENSP00000331258 | Divergent protein kinase domain 2B. | Protein O-mannose kinase; Protein O-mannose kinase that specifically mediates phosphorylation at the 6-position of an O-mannose of the trisaccharide (N-acetylgalactosamine (GalNAc)-beta-1,3-N-acetylglucosamine (GlcNAc)- beta-1,4-mannose) to generate phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-1,3-N-acetylglucosamine-beta-1,4- (phosphate-6-)mannose). Phosphorylated O-mannosyl trisaccharide is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Only [...] | 0.509 |
EVI5 | DIPK1A | ENSP00000440826 | ENSP00000359333 | Ecotropic viral integration site 5 protein homolog; Functions as a regulator of cell cycle progression by stabilizing the FBXO5 protein and promoting cyclin-A accumulation during interphase. May play a role in cytokinesis. | Divergent protein kinase domain 1A. | 0.530 |