STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAM71E1Protein FAM71E1; Family with sequence similarity 71 member E1. (247 aa)    
Predicted Functional Partners:
TMEM89
Transmembrane protein 89.
      
 0.608
FOXL2NB
FOXL2 neighbor.
      
 0.578
OR4F21
Olfactory receptor 4F21; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.573
EMC10
ER membrane protein complex subunit 10; Promotes angiogenesis and tissue repair in the heart after myocardial infarction. Stimulates cardiac endothelial cell migration and outgrowth via the activation of p38 MAPK, PAK and MAPK2 signaling pathways.
   
  
 0.571
ZNF487
Putative zinc finger protein 487; May be involved in transcriptional regulation.
      
 0.570
PDHA2
Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.
      
 0.542
SLC5A9
Sodium/glucose cotransporter 4; Involved in sodium-dependent transport of D-mannose, D- glucose and D-fructose; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
      
 0.533
MORN5
MORN repeat containing 5.
   
  
 0.519
CCER1
Coiled-coil glutamate rich protein 1.
      
 0.507
TEX33
Testis-expressed protein 33; Testis expressed 33.
   
  
 0.507
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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