node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CLBA1 | LRATD2 | ENSP00000450114 | ENSP00000302578 | Uncharacterized protein CLBA1; Clathrin binding box of aftiphilin containing 1. | Protein LRATD2; LRAT domain containing 2; Belongs to the LRATD family. | 0.507 |
CLBA1 | VWA5B2 | ENSP00000450114 | ENSP00000398688 | Uncharacterized protein CLBA1; Clathrin binding box of aftiphilin containing 1. | Von Willebrand factor A domain containing 5B2. | 0.609 |
CTNNA1 | LRATD2 | ENSP00000304669 | ENSP00000302578 | Catenin alpha-1; Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E- and N-cadherins. Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be much more dynamic than E-cadherin/catenin complexes and [...] | Protein LRATD2; LRAT domain containing 2; Belongs to the LRATD family. | 0.753 |
DIPK2B | GSDMC | ENSP00000381086 | ENSP00000276708 | Divergent protein kinase domain 2B. | Gasdermin-C; The N-terminal moiety promotes pyroptosis. May be acting by homooligomerizing within the membrane and forming pores. The physiological relevance of this observation is unknown (Probable). | 0.413 |
DIPK2B | LRATD2 | ENSP00000381086 | ENSP00000302578 | Divergent protein kinase domain 2B. | Protein LRATD2; LRAT domain containing 2; Belongs to the LRATD family. | 0.428 |
GSDMC | DIPK2B | ENSP00000276708 | ENSP00000381086 | Gasdermin-C; The N-terminal moiety promotes pyroptosis. May be acting by homooligomerizing within the membrane and forming pores. The physiological relevance of this observation is unknown (Probable). | Divergent protein kinase domain 2B. | 0.413 |
GSDMC | LRATD2 | ENSP00000276708 | ENSP00000302578 | Gasdermin-C; The N-terminal moiety promotes pyroptosis. May be acting by homooligomerizing within the membrane and forming pores. The physiological relevance of this observation is unknown (Probable). | Protein LRATD2; LRAT domain containing 2; Belongs to the LRATD family. | 0.601 |
LRATD2 | CLBA1 | ENSP00000302578 | ENSP00000450114 | Protein LRATD2; LRAT domain containing 2; Belongs to the LRATD family. | Uncharacterized protein CLBA1; Clathrin binding box of aftiphilin containing 1. | 0.507 |
LRATD2 | CTNNA1 | ENSP00000302578 | ENSP00000304669 | Protein LRATD2; LRAT domain containing 2; Belongs to the LRATD family. | Catenin alpha-1; Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E- and N-cadherins. Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be much more dynamic than E-cadherin/catenin complexes and [...] | 0.753 |
LRATD2 | DIPK2B | ENSP00000302578 | ENSP00000381086 | Protein LRATD2; LRAT domain containing 2; Belongs to the LRATD family. | Divergent protein kinase domain 2B. | 0.428 |
LRATD2 | GSDMC | ENSP00000302578 | ENSP00000276708 | Protein LRATD2; LRAT domain containing 2; Belongs to the LRATD family. | Gasdermin-C; The N-terminal moiety promotes pyroptosis. May be acting by homooligomerizing within the membrane and forming pores. The physiological relevance of this observation is unknown (Probable). | 0.601 |
LRATD2 | PLAAT1 | ENSP00000302578 | ENSP00000498228 | Protein LRATD2; LRAT domain containing 2; Belongs to the LRATD family. | Phospholipase A and acyltransferase 1; Exhibits both phospholipase A1/2 and acyltransferase activities. Shows phospholipase A1 (PLA1) and A2 (PLA2) activity, catalyzing the calcium-independent release of fatty acids from the sn-1 or sn-2 position of glycerophospholipids. Shows O-acyltransferase activity, catalyzing the transfer of a fatty acyl group from glycerophospholipid to the hydroxyl group of lysophospholipid. Shows N-acyltransferase activity, catalyzing the calcium-independent transfer of a fatty acyl group at the sn-1 position of phosphatidylcholine (PC) and other glycerophosph [...] | 0.595 |
LRATD2 | PLAAT2 | ENSP00000302578 | ENSP00000255695 | Protein LRATD2; LRAT domain containing 2; Belongs to the LRATD family. | Phospholipase A and acyltransferase 2; Exhibits both phospholipase A1/2 and acyltransferase activities. Shows phospholipase A1 (PLA1) and A2 (PLA2) activity, catalyzing the calcium-independent release of fatty acids from the sn-1 or sn-2 position of glycerophospholipids. For most substrates, PLA1 activity is much higher than PLA2 activity. Shows O- acyltransferase activity, catalyzing the transfer of a fatty acyl group from glycerophospholipid to the hydroxyl group of lysophospholipid. Shows N-acyltransferase activity, catalyzing the calcium-independent transfer of a fatty acyl group a [...] | 0.496 |
LRATD2 | POU5F1B | ENSP00000302578 | ENSP00000419298 | Protein LRATD2; LRAT domain containing 2; Belongs to the LRATD family. | Putative POU domain, class 5, transcription factor 1B; Shows weak transcriptional activator activity. | 0.642 |
LRATD2 | UROD | ENSP00000302578 | ENSP00000246337 | Protein LRATD2; LRAT domain containing 2; Belongs to the LRATD family. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.714 |
LRATD2 | VWA5B2 | ENSP00000302578 | ENSP00000398688 | Protein LRATD2; LRAT domain containing 2; Belongs to the LRATD family. | Von Willebrand factor A domain containing 5B2. | 0.429 |
LRATD2 | ZNF572 | ENSP00000302578 | ENSP00000319305 | Protein LRATD2; LRAT domain containing 2; Belongs to the LRATD family. | Zinc finger protein 572; May be involved in transcriptional regulation. | 0.472 |
PLAAT1 | LRATD2 | ENSP00000498228 | ENSP00000302578 | Phospholipase A and acyltransferase 1; Exhibits both phospholipase A1/2 and acyltransferase activities. Shows phospholipase A1 (PLA1) and A2 (PLA2) activity, catalyzing the calcium-independent release of fatty acids from the sn-1 or sn-2 position of glycerophospholipids. Shows O-acyltransferase activity, catalyzing the transfer of a fatty acyl group from glycerophospholipid to the hydroxyl group of lysophospholipid. Shows N-acyltransferase activity, catalyzing the calcium-independent transfer of a fatty acyl group at the sn-1 position of phosphatidylcholine (PC) and other glycerophosph [...] | Protein LRATD2; LRAT domain containing 2; Belongs to the LRATD family. | 0.595 |
PLAAT2 | LRATD2 | ENSP00000255695 | ENSP00000302578 | Phospholipase A and acyltransferase 2; Exhibits both phospholipase A1/2 and acyltransferase activities. Shows phospholipase A1 (PLA1) and A2 (PLA2) activity, catalyzing the calcium-independent release of fatty acids from the sn-1 or sn-2 position of glycerophospholipids. For most substrates, PLA1 activity is much higher than PLA2 activity. Shows O- acyltransferase activity, catalyzing the transfer of a fatty acyl group from glycerophospholipid to the hydroxyl group of lysophospholipid. Shows N-acyltransferase activity, catalyzing the calcium-independent transfer of a fatty acyl group a [...] | Protein LRATD2; LRAT domain containing 2; Belongs to the LRATD family. | 0.496 |
POU5F1B | LRATD2 | ENSP00000419298 | ENSP00000302578 | Putative POU domain, class 5, transcription factor 1B; Shows weak transcriptional activator activity. | Protein LRATD2; LRAT domain containing 2; Belongs to the LRATD family. | 0.642 |