node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FAM227B | FPGT | ENSP00000299338 | ENSP00000359935 | Protein FAM227B; Family with sequence similarity 227 member B. | Fucose-1-phosphate guanylyltransferase; Catalyzes the formation of GDP-L-fucose from GTP and L- fucose-1-phosphate. Functions as a salvage pathway to reutilize L- fucose arising from the turnover of glycoproteins and glycolipids. | 0.511 |
FAM227B | LRRIQ3 | ENSP00000299338 | ENSP00000346414 | Protein FAM227B; Family with sequence similarity 227 member B. | Leucine rich repeats and IQ motif containing 3. | 0.734 |
FCSK | FPGT | ENSP00000288078 | ENSP00000359935 | L-fucose kinase; Takes part in the salvage pathway for reutilization of fucose from the degradation of oligosaccharides. | Fucose-1-phosphate guanylyltransferase; Catalyzes the formation of GDP-L-fucose from GTP and L- fucose-1-phosphate. Functions as a salvage pathway to reutilize L- fucose arising from the turnover of glycoproteins and glycolipids. | 0.953 |
FCSK | GMDS | ENSP00000288078 | ENSP00000370194 | L-fucose kinase; Takes part in the salvage pathway for reutilization of fucose from the degradation of oligosaccharides. | GDP-mannose 4,6 dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily. | 0.784 |
FCSK | SLC35C1 | ENSP00000288078 | ENSP00000313318 | L-fucose kinase; Takes part in the salvage pathway for reutilization of fucose from the degradation of oligosaccharides. | GDP-fucose transporter 1; Involved in GDP-fucose import from the cytoplasm into the Golgi lumen; Belongs to the TPT transporter family. SLC35C subfamily. | 0.625 |
FCSK | SLC35C2 | ENSP00000288078 | ENSP00000318960 | L-fucose kinase; Takes part in the salvage pathway for reutilization of fucose from the degradation of oligosaccharides. | Solute carrier family 35 member C2; May play an important role in the cellular response to tissue hypoxia. May be either a GDP-fucose transporter that competes with SLC35C1 for GDP-fucose, or a factor that otherwise enhances the fucosylation of Notch and is required for optimal Notch signaling in mammalian cells. | 0.464 |
FCSK | TSTA3 | ENSP00000288078 | ENSP00000398803 | L-fucose kinase; Takes part in the salvage pathway for reutilization of fucose from the degradation of oligosaccharides. | GDP-L-fucose synthase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. | 0.825 |
FPGT | FAM227B | ENSP00000359935 | ENSP00000299338 | Fucose-1-phosphate guanylyltransferase; Catalyzes the formation of GDP-L-fucose from GTP and L- fucose-1-phosphate. Functions as a salvage pathway to reutilize L- fucose arising from the turnover of glycoproteins and glycolipids. | Protein FAM227B; Family with sequence similarity 227 member B. | 0.511 |
FPGT | FCSK | ENSP00000359935 | ENSP00000288078 | Fucose-1-phosphate guanylyltransferase; Catalyzes the formation of GDP-L-fucose from GTP and L- fucose-1-phosphate. Functions as a salvage pathway to reutilize L- fucose arising from the turnover of glycoproteins and glycolipids. | L-fucose kinase; Takes part in the salvage pathway for reutilization of fucose from the degradation of oligosaccharides. | 0.953 |
FPGT | GGPS1 | ENSP00000359935 | ENSP00000282841 | Fucose-1-phosphate guanylyltransferase; Catalyzes the formation of GDP-L-fucose from GTP and L- fucose-1-phosphate. Functions as a salvage pathway to reutilize L- fucose arising from the turnover of glycoproteins and glycolipids. | Geranylgeranyl pyrophosphate synthase; Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate, an important precursor of carotenoids and geranylated proteins. | 0.551 |
FPGT | GMDS | ENSP00000359935 | ENSP00000370194 | Fucose-1-phosphate guanylyltransferase; Catalyzes the formation of GDP-L-fucose from GTP and L- fucose-1-phosphate. Functions as a salvage pathway to reutilize L- fucose arising from the turnover of glycoproteins and glycolipids. | GDP-mannose 4,6 dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily. | 0.735 |
FPGT | H7C0V5_HUMAN | ENSP00000359935 | ENSP00000432016 | Fucose-1-phosphate guanylyltransferase; Catalyzes the formation of GDP-L-fucose from GTP and L- fucose-1-phosphate. Functions as a salvage pathway to reutilize L- fucose arising from the turnover of glycoproteins and glycolipids. | ANKHD1-EIF4EBP3 readthrough. | 0.455 |
FPGT | LRRIQ3 | ENSP00000359935 | ENSP00000346414 | Fucose-1-phosphate guanylyltransferase; Catalyzes the formation of GDP-L-fucose from GTP and L- fucose-1-phosphate. Functions as a salvage pathway to reutilize L- fucose arising from the turnover of glycoproteins and glycolipids. | Leucine rich repeats and IQ motif containing 3. | 0.736 |
FPGT | SLC35C1 | ENSP00000359935 | ENSP00000313318 | Fucose-1-phosphate guanylyltransferase; Catalyzes the formation of GDP-L-fucose from GTP and L- fucose-1-phosphate. Functions as a salvage pathway to reutilize L- fucose arising from the turnover of glycoproteins and glycolipids. | GDP-fucose transporter 1; Involved in GDP-fucose import from the cytoplasm into the Golgi lumen; Belongs to the TPT transporter family. SLC35C subfamily. | 0.549 |
FPGT | SLC35C2 | ENSP00000359935 | ENSP00000318960 | Fucose-1-phosphate guanylyltransferase; Catalyzes the formation of GDP-L-fucose from GTP and L- fucose-1-phosphate. Functions as a salvage pathway to reutilize L- fucose arising from the turnover of glycoproteins and glycolipids. | Solute carrier family 35 member C2; May play an important role in the cellular response to tissue hypoxia. May be either a GDP-fucose transporter that competes with SLC35C1 for GDP-fucose, or a factor that otherwise enhances the fucosylation of Notch and is required for optimal Notch signaling in mammalian cells. | 0.620 |
FPGT | TNNI3K | ENSP00000359935 | ENSP00000322251 | Fucose-1-phosphate guanylyltransferase; Catalyzes the formation of GDP-L-fucose from GTP and L- fucose-1-phosphate. Functions as a salvage pathway to reutilize L- fucose arising from the turnover of glycoproteins and glycolipids. | Serine/threonine-protein kinase TNNI3K; May play a role in cardiac physiology. Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. | 0.804 |
FPGT | TSTA3 | ENSP00000359935 | ENSP00000398803 | Fucose-1-phosphate guanylyltransferase; Catalyzes the formation of GDP-L-fucose from GTP and L- fucose-1-phosphate. Functions as a salvage pathway to reutilize L- fucose arising from the turnover of glycoproteins and glycolipids. | GDP-L-fucose synthase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. | 0.965 |
GGPS1 | FPGT | ENSP00000282841 | ENSP00000359935 | Geranylgeranyl pyrophosphate synthase; Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate, an important precursor of carotenoids and geranylated proteins. | Fucose-1-phosphate guanylyltransferase; Catalyzes the formation of GDP-L-fucose from GTP and L- fucose-1-phosphate. Functions as a salvage pathway to reutilize L- fucose arising from the turnover of glycoproteins and glycolipids. | 0.551 |
GMDS | FCSK | ENSP00000370194 | ENSP00000288078 | GDP-mannose 4,6 dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily. | L-fucose kinase; Takes part in the salvage pathway for reutilization of fucose from the degradation of oligosaccharides. | 0.784 |
GMDS | FPGT | ENSP00000370194 | ENSP00000359935 | GDP-mannose 4,6 dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily. | Fucose-1-phosphate guanylyltransferase; Catalyzes the formation of GDP-L-fucose from GTP and L- fucose-1-phosphate. Functions as a salvage pathway to reutilize L- fucose arising from the turnover of glycoproteins and glycolipids. | 0.735 |