node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AMY1B | AMY2A | ENSP00000330484 | ENSP00000481450 | Amylase alpha 1B; Belongs to the glycosyl hydrolase 13 family. | Pancreatic alpha-amylase; Amylase alpha 2A. | 0.901 |
AMY1B | AMY2B | ENSP00000330484 | ENSP00000354610 | Amylase alpha 1B; Belongs to the glycosyl hydrolase 13 family. | Amylase alpha 2B; Belongs to the glycosyl hydrolase 13 family. | 0.915 |
AMY1B | GAA | ENSP00000330484 | ENSP00000305692 | Amylase alpha 1B; Belongs to the glycosyl hydrolase 13 family. | 70 kDa lysosomal alpha-glucosidase; Essential for the degradation of glycogen in lysosomes. Has highest activity on alpha-1,4-linked glycosidic linkages, but can also hydrolyze alpha-1,6-linked glucans. | 0.943 |
AMY1B | HK1 | ENSP00000330484 | ENSP00000494664 | Amylase alpha 1B; Belongs to the glycosyl hydrolase 13 family. | Hexokinase-1; Catalyzes the phosphorylation of various hexoses, such as D- glucose, D-glucosamine, D-fructose, D-mannose and 2-deoxy-D-glucose, to hexose 6-phosphate (D-glucose 6-phosphate, D-glucosamine 6-phosphate, D-fructose 6-phosphate, D-mannose 6-phosphate and 2-deoxy-D-glucose 6- phosphate, respectively). Does not phosphorylate N-acetyl-D-glucosamine. Mediates the initial step of glycolysis by catalyzing phosphorylation of D-glucose to D-glucose 6-phosphate (By similarity). Involved in innate immunity and inflammation by acting as a pattern recognition receptor for bacterial pep [...] | 0.416 |
AMY1B | HK3 | ENSP00000330484 | ENSP00000292432 | Amylase alpha 1B; Belongs to the glycosyl hydrolase 13 family. | Hexokinase-3; Catalyzes the phosphorylation of hexose, such as D-glucose and D-fructose, to hexose 6-phosphate (D-glucose 6-phosphate and D- fructose 6-phosphate, respectively). Mediates the initial step of glycolysis by catalyzing phosphorylation of D-glucose to D-glucose 6-phosphate. Belongs to the hexokinase family. | 0.450 |
AMY1B | MGAM | ENSP00000330484 | ENSP00000447378 | Amylase alpha 1B; Belongs to the glycosyl hydrolase 13 family. | Maltase-glucoamylase, intestinal; May serve as an alternate pathway for starch digestion when luminal alpha-amylase activity is reduced because of immaturity or malnutrition. May play a unique role in the digestion of malted dietary oligosaccharides used in food manufacturing. | 0.998 |
AMY1B | SI | ENSP00000330484 | ENSP00000264382 | Amylase alpha 1B; Belongs to the glycosyl hydrolase 13 family. | Sucrase-isomaltase, intestinal; Plays an important role in the final stage of carbohydrate digestion. Isomaltase activity is specific for both alpha-1,4- and alpha-1,6-oligosaccharides; Belongs to the glycosyl hydrolase 31 family. | 0.992 |
AMY2A | AMY1B | ENSP00000481450 | ENSP00000330484 | Pancreatic alpha-amylase; Amylase alpha 2A. | Amylase alpha 1B; Belongs to the glycosyl hydrolase 13 family. | 0.901 |
AMY2A | AMY2B | ENSP00000481450 | ENSP00000354610 | Pancreatic alpha-amylase; Amylase alpha 2A. | Amylase alpha 2B; Belongs to the glycosyl hydrolase 13 family. | 0.960 |
AMY2A | GAA | ENSP00000481450 | ENSP00000305692 | Pancreatic alpha-amylase; Amylase alpha 2A. | 70 kDa lysosomal alpha-glucosidase; Essential for the degradation of glycogen in lysosomes. Has highest activity on alpha-1,4-linked glycosidic linkages, but can also hydrolyze alpha-1,6-linked glucans. | 0.956 |
AMY2A | MGAM | ENSP00000481450 | ENSP00000447378 | Pancreatic alpha-amylase; Amylase alpha 2A. | Maltase-glucoamylase, intestinal; May serve as an alternate pathway for starch digestion when luminal alpha-amylase activity is reduced because of immaturity or malnutrition. May play a unique role in the digestion of malted dietary oligosaccharides used in food manufacturing. | 0.998 |
AMY2A | SI | ENSP00000481450 | ENSP00000264382 | Pancreatic alpha-amylase; Amylase alpha 2A. | Sucrase-isomaltase, intestinal; Plays an important role in the final stage of carbohydrate digestion. Isomaltase activity is specific for both alpha-1,4- and alpha-1,6-oligosaccharides; Belongs to the glycosyl hydrolase 31 family. | 0.993 |
AMY2B | AMY1B | ENSP00000354610 | ENSP00000330484 | Amylase alpha 2B; Belongs to the glycosyl hydrolase 13 family. | Amylase alpha 1B; Belongs to the glycosyl hydrolase 13 family. | 0.915 |
AMY2B | AMY2A | ENSP00000354610 | ENSP00000481450 | Amylase alpha 2B; Belongs to the glycosyl hydrolase 13 family. | Pancreatic alpha-amylase; Amylase alpha 2A. | 0.960 |
AMY2B | GAA | ENSP00000354610 | ENSP00000305692 | Amylase alpha 2B; Belongs to the glycosyl hydrolase 13 family. | 70 kDa lysosomal alpha-glucosidase; Essential for the degradation of glycogen in lysosomes. Has highest activity on alpha-1,4-linked glycosidic linkages, but can also hydrolyze alpha-1,6-linked glucans. | 0.943 |
AMY2B | HK3 | ENSP00000354610 | ENSP00000292432 | Amylase alpha 2B; Belongs to the glycosyl hydrolase 13 family. | Hexokinase-3; Catalyzes the phosphorylation of hexose, such as D-glucose and D-fructose, to hexose 6-phosphate (D-glucose 6-phosphate and D- fructose 6-phosphate, respectively). Mediates the initial step of glycolysis by catalyzing phosphorylation of D-glucose to D-glucose 6-phosphate. Belongs to the hexokinase family. | 0.413 |
AMY2B | MGAM | ENSP00000354610 | ENSP00000447378 | Amylase alpha 2B; Belongs to the glycosyl hydrolase 13 family. | Maltase-glucoamylase, intestinal; May serve as an alternate pathway for starch digestion when luminal alpha-amylase activity is reduced because of immaturity or malnutrition. May play a unique role in the digestion of malted dietary oligosaccharides used in food manufacturing. | 0.998 |
AMY2B | SI | ENSP00000354610 | ENSP00000264382 | Amylase alpha 2B; Belongs to the glycosyl hydrolase 13 family. | Sucrase-isomaltase, intestinal; Plays an important role in the final stage of carbohydrate digestion. Isomaltase activity is specific for both alpha-1,4- and alpha-1,6-oligosaccharides; Belongs to the glycosyl hydrolase 31 family. | 0.992 |
GAA | AMY1B | ENSP00000305692 | ENSP00000330484 | 70 kDa lysosomal alpha-glucosidase; Essential for the degradation of glycogen in lysosomes. Has highest activity on alpha-1,4-linked glycosidic linkages, but can also hydrolyze alpha-1,6-linked glucans. | Amylase alpha 1B; Belongs to the glycosyl hydrolase 13 family. | 0.943 |
GAA | AMY2A | ENSP00000305692 | ENSP00000481450 | 70 kDa lysosomal alpha-glucosidase; Essential for the degradation of glycogen in lysosomes. Has highest activity on alpha-1,4-linked glycosidic linkages, but can also hydrolyze alpha-1,6-linked glucans. | Pancreatic alpha-amylase; Amylase alpha 2A. | 0.956 |